(1) A family in which a gene (MRX2) is segregating for an X-linked syndrome of mental retardation, short stature, microcephaly, brachycephaly, spastic diplegia, small testes and possible intra-uterine growth retardation is described.
(2) A 2-month-old boy with delayed growth and development, brachycephaly, large anterior fontanelle, low-set folded ears, micrognathia, aortic coarctation, floppy abdominal muscles, and pes varus, was found to have a 46,XY,del(16)(q2100q2300) de novo karyotype.
(3) Clinical manifestations include brachycephaly and a flat mid-face; brachydactyly; short, broad hands; mental retardation; and aberrant behaviour, including hyperactivity.
(4) The phenotype includes brachycephaly, club feet, delay of growth and development, and hypertelorism with upslanted palpebral fissures.
(5) Their clinical manifestations included brachycephaly, midface hypoplasia, prognathism, upper lip eversion, short and broad hands with short fingers, clinodactyly of the fifth fingers, fingertip pads, moderate mental retardation, and behavior problems.
(6) Additionally, he had brachycephaly, a high arched palate, hypospadias, a malformed left external ear, and bilateral finger contractures.
(7) The characteristic findings are mental retardation, characteristic facies, narrow forehead, bushy eyebrows with synophrys, hypertelorism, broad nose, wide philtrum, triangular-shaped mouth, short neck, marked maxillary hypoplasia, a low hairline (especially posteriorly in the midline on the neck), brachycephaly, calcified clinoid ligements, and multiple bony abnormalities in the upper thoracic vertebrae and sometimes in the cervical region, together with a variety of deformities of the upper ribs.
(8) A family is described in which 15 persons in five generations are affected with a complex of skeletal malformations which variably includes peculiar asymmetric facies, delayed closure of large fontanels, brachycephaly, acrocephaly, brachydactyly, cutaneous syndactyly, broad great toes, and mild shortness of stature.
(9) Callosa of subjects with Down syndrome were distinctively rounded in form, consistent with Down syndrome brachycephaly.
(10) The best operative period is the first year of life, 2 to 3 months of age for the brachycephalies, and 6 to 9 months of age for the other craniosynostoses.
(11) The effectiveness of the "floating forehead" operation for treating brachycephaly in infants has been assessed.
(12) The three affected males had severe mental retardation (IQ 20 to 30), mutism, growth failure, frequent infections, seizures, and the following minor anomalies: brachycephaly, frontal hair whorl, square face, large mouth, thick lips, and prognathism.
(13) Micromelia and brachycephaly were recognized in affected embryos after 9 days while lethality occurred mainly after 16 days of incubation.
(14) A female child with brachycephaly, hypertelorism, convergent strabismus, interstitial keratitis, analgesia on both sides of the face, absent corneal reflexes, and focal congenital alopecia of a zone of the occipital and posterior parietal scalp is presented.
(15) Radiological features include premature synostosis of the coronal suture, brachycephaly, and maxillary under-development.
(16) Description of a boy aged 20 months presenting growth and mental retardation as well as several minor anomalies : brachycephaly, antimongoloid slant of the palpebral fissures, dystopia canthorum, broad nose, low set ears and short fingers.
(17) They all had a similar phenotype with mental retardation, behavioural problems, facial dysmorphism, brachycephaly, a broad face with a flat midface, and short and broad hands.
(18) The common clinical findings were broad flat midface with brachycephaly, broad nasal bridge, brachydactyly, speech delay, and hoarse, deep voice.
(19) Principle clinical features include: Anatomic - microcephaly; bilateral, convergent strabismus; epicanthus; brachycephaly; bulbar nose; sparse hair; partial soft tissue syndactylism between 2nd and 3rd fingers which are slightly tapered; whorls on all 10 fingers; mild prognathism; solitary kidney; vaginal stenosis; vesicoureteral reflux; asymmetric feet; and subluxation of peroneal tendons around the fibula with severe pronation and heal valgus deformity.
(20) Four of seven cases (57%) with brachycephaly showed low perfusion areas in either of frontal lobes, occipital lobes, and cerebellum.
Flattened
Definition:
(imp. & p. p.) of Flatten
Example Sentences:
(1) In 22 cases (63%), retinal detachment was at least partially flattened in the area of the posterior pole of the eye.
(2) Opsin becomes incorporated into the disk membrane by a process of membrane expansion and fusion to form the flattened disks of the outer segment.
(3) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(4) Six patients, two of whom developed sciatic neuropathy, demonstrated complete flattening of the SSEP.
(5) A radical rearrangement of the organism occurred gradually: initially oval in shape, the parasite became round, then elongated, flattened, and underwent cytokinesis.
(6) The changes included swelling, blunting, and flattening of epithelial foot processes, were accompanied by decreased stainability of glomerular anionic sites, and were largely reversed by subsequent perfusion with the polyanion heparin.
(7) In an effort to decrease the treatment time for this technique, the flattening filter has been removed from an AECL Therac-6 linear accelerator and the characteristics of the resulting beam have been measured.
(8) In the cis-trans axis of the Golgi apparatus the following compartments were observed: (a) On the cis face there was a continuous osmiophilic tubular network referred to as the cis element; (b) a cis compartment composed of 3 or 4 NADPase-positive saccules perforated with pores in register forming wells that contained small vesicles; (c) a trans compartment composed of 1 or 2 TPPAse-positive elements underlying the NADPase ones, followed by 1 or 2 CMPase-positive elements that showed a flattened saccular part continuous with a network of anastomotic tubules.
(9) The flattening of neutrophils occurred soon after settling, and was not followed by extension.
(10) The streets of Jiegu are now littered with concrete remnants of modern structures and the flattened mud and painted wood of traditional Tibetan buildings.
(11) The EWRGP group showed a mean flattening in corneal curvature of 0.11 and 0.15 mm in the flattest and steepest corneal meridians, respectively.
(12) The lining epithelium was a single layer of flattened or cuboidal endocervical cells.
(13) The first eigenvector, when represented by grey scale maps depicting a pair of eyes, reveals that, as average threshold increases, the visual field rises and flattens, like an umbrella that, initially closed, is simultaneously opened and thrust upwards.
(14) In older children, there were a low vertebral signal and disappearance of the disc-vertebra borders on T1-weighted images and a high vertebral signal with a decreased and flattened disc signal on T2-weighted images.
(15) Poorly-differentiated tissue produced a more haphazard out-growth of pleomorphic cells with few processes and flattened pseudopodia.
(16) In the past, ovarian cancer was more common in higher social classes, but sociocultural differences seem to have flattened off over recent decades.
(17) In the SEM three corresponding types were identified, a relatively smooth spherical type, a highly ruffled type and a fairly smooth flattened type.
(18) This change in shape varied from a slight flattening of the LV and IVS during diastole to total reversal of the normal direction of septal curvature such that the IVS became concave toward the RV and convex toward the LV.
(19) By phase-contrast microscopy of living cells and in more detail by scanning electron microscopy, the megakaryocytes showed a nonreversible adherence, an extensive formation of filopodia around the periphery like the rays of the sun, and a tendency toward flattening.
(20) The nerve bundles, encircled by basal lamina, were enclosed by a thin connective tissue layer and by flattened fibroblast-like cells.