(n.) The whitish mass of soft matter (the center of the nervous system, and the seat of consciousness and volition) which is inclosed in the cartilaginous or bony cranium of vertebrate animals. It is simply the anterior termination of the spinal cord, and is developed from three embryonic vesicles, whose cavities are connected with the central canal of the cord; the cavities of the vesicles become the central cavities, or ventricles, and the walls thicken unequally and become the three segments, the fore-, mid-, and hind-brain.
(n.) The anterior or cephalic ganglion in insects and other invertebrates.
(n.) The organ or seat of intellect; hence, the understanding.
(n.) The affections; fancy; imagination.
(v. t.) To dash out the brains of; to kill by beating out the brains. Hence, Fig.: To destroy; to put an end to; to defeat.
(v. t.) To conceive; to understand.
Example Sentences:
(1) Here we have asked whether protection from blood-borne antigens afforded by the blood-brain barrier is related to the lack of MHC expression.
(2) The extents of phospholipid hydrolysis were relatively low in brain homogenates, synaptic plasma membranes and heart ventricular muscle.
(3) First results let us assume that clinically silent TIAs also (in analogy to clinically silent brain infarctions) could be detected and located.
(4) Brain and ganglia of embryonic Periplaneta americana were grown for 2 to 3 weeks in a chemically defined medium.
(5) The results indicated that neuropsychological measures may serve to broaden the concept of intelligence and that a brain-related criterion may contribute to a fuller understanding of its nature.
(6) To quantify the size of the lesion in mice, the area of the infarct on the brain surface was assessed planimetrically 48 h after MCA occlusion by transcardial perfusion of carbon black.
(7) However, CT will be insensitive in the detection of the more cephalic proximal lesions, especially those in the brain stem, basal cisterns, and skull base.
(8) The fine structure of neurofibrillary tangles in the hippocampal gyrus, substantia nigra, pontine nuclei and locus coeruleus of the brain was postmortem studied in a case of progressive supranuclear palsy.
(9) We similarly evaluated the ability of other phospholipids to form stable foam at various concentrations and ethanol volume fractions and found: bovine brain sphingomyelin greater than dipalmitoyl 3-sn-phosphatidylcholine greater than egg sphingomyelin greater than egg lecithin greater than phosphatidylglycerol.
(10) This study examined the [3H]5-HT-releasing properties of 3,4-methylenedioxymethamphetamine (MDMA) and related agents, all of which cause significant release of [3H]5-HT from rat brain synaptosomes.
(11) In the present investigation we monitored the incorporation of [14C] from [U-14C]glucose into various rat brain glycolytic intermediates of conscious and pentobarbital-anesthetized animals.
(12) Cranial MRI revealed delayed myelination in the white matter but no brain malformation.
(13) When compared with lissencephalic species, a great horizontal fibrillary system (which is vertically arranged in gyral regions) was observed in convoluted brains.
(14) In more than 70 per cent of these, brain injury is the decisive lethal factor.
(15) Brain damage may be followed by a number of dynamic events including reactive synaptogenesis, rerouting of axons to unusual locations and altered axon retraction processes.
(16) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
(17) The regional distribution of beta-adrenoceptor subtypes was found to be similar to that seen in the rat brain.
(18) We assessed changes in brain water content, as reflected by changes in tissue density, during the early recirculation period following severe forebrain ischemia.
(19) If tracer is introduced into the carotid artery after osmotic treatment, brain uptake is increased by a net factor of 50 (a factor of 70 due to elevation of PA, multiplied by 7 due to infusion by the carotid route) as compared to uptake by normal, untreated brain with infusion into a peripheral vein.
(20) This study examined both the effect of variations in optical fiber tip and in light wavelength on laser-induced hyperthermia in rat brain.
Forebrain
Definition:
(n.) The anterior of the three principal divisions of the brain, including the prosencephalon and thalamencephalon. Sometimes restricted to the prosencephalon only. See Brain.
Example Sentences:
(1) We assessed changes in brain water content, as reflected by changes in tissue density, during the early recirculation period following severe forebrain ischemia.
(2) To study these changes more thoroughly, specific monoclonal antibodies of the A and B subunits of calcineurin (protein phosphatase 2B) were raised, and regional alterations in the immunoreactivity of calcineurin in the rat hippocampus were investigated after a transient forebrain ischemic insult causing selective and delayed hippocampal CA1 pyramidal cell damage.
(3) The analogy with infant sleep patterns and results of studies of brain function in narcoleptics suggest that forebrain inhibitory processes are more important in narcoleptic symptomology than is brainstem dysfunction.
(4) Neural plate damage, expressed during a critical period of forebrain development, was evaluated 48 h post-insonation.
(5) This result contraindicates a general permissive-requisite role for forebrain NE for the mammalian brain's plasticity during its critical periods.
(6) Key findings include a progressive degeneration of these cholinergic neurons characterized by the formation of immunoreactively atypical NFT, the loss of intraneuronal lipofuscin, a lack of senile plaque and beta-amyloid deposition within the basal forebrain, and end-stage gliosis without residual extracellular NFT.
(7) The hypothalamus is a most complex part of the CNS having rich interconnections with forebrain, limbic and brainstem structures.
(8) Results suggest that the locomotor activating effects of CRF may be due to an activation of CRF receptors in the ventral forebrain, a region rich in CRF cell bodies and projections.
(9) Sixty days after 5,7-DHT administration, immunoreactive serotonin in the forebrain, particularly the suprachiasmatic nuclei and intergeniculate leaflets, was severely depleted in 16 animals, moderately depleted in four and only slightly affected in four.
(10) Twelve-hour polygraph recordings were made before and at various intervals after basal forebrain damage in a total of eight cats.
(11) Impairments of cognition and memory in AD result from disease of neurons in a number of regions, including brainstem, basal forebrain, amygdala, hippocampus, and neocortex.
(12) Patients with bilateral forebrain disease may commonly manifest the syndrome of pathologic laughing and weeping.
(13) Ovariectomized (OVXed) animals were implanted with chronic cannulas in the basal forebrain.
(14) Thus, neurons of the habenula and interpeduncular nucleus are under the direct and indirect influence of septal neurons within the limbic forebrain circuit.
(15) A detailed description is offered on supply of the nucleus preopticus medialis, lateralis, suprachiasmatis and periventricularis, as well as of the nucleus interstitialis striae criminalis and of the preoptic portion of the medical forebrain bundle.
(16) The regional distribution of forebrain neurons expressing preprocholecystokinin (preproCCK) mRNA was examined using in situ and blot hybridization analysis.
(17) Some LC neurones were activated trans-synaptically by stimulation of those forebrain sites which received axonal projections from LC.
(18) Other antidromically activated neurons in the vasodepressor region may be inhibitory vasomotor cells with a function relatively independent of baroreceptor inputs, or they may be A1 catecholamine neurons, with axons passing through the rostral medulla en route to the forebrain.
(19) Fewer, but still ample numbers, of SP-reactive axons are present also in the ventral tegmental and retrorubral areas of the midbrain tegmentum and in the ventral pallidum of the basal forebrain, but only sparse ME-reactive axons are present in these areas.
(20) 5-HT containing terminals and fibers also were observed in the mesencephalon and appeared to run rostrally in the medial part of the medial forebrain bundle.