(v. t.) To strain apart; to sever by fracture; to divide with violence; as, to break a rope or chain; to break a seal; to break an axle; to break rocks or coal; to break a lock.
(v. t.) To lay open as by breaking; to divide; as, to break a package of goods.
(v. t.) To lay open, as a purpose; to disclose, divulge, or communicate.
(v. t.) To infringe or violate, as an obligation, law, or promise.
(v. t.) To interrupt; to destroy the continuity of; to dissolve or terminate; as, to break silence; to break one's sleep; to break one's journey.
(v. t.) To destroy the completeness of; to remove a part from; as, to break a set.
(v. t.) To destroy the arrangement of; to throw into disorder; to pierce; as, the cavalry were not able to break the British squares.
(v. t.) To shatter to pieces; to reduce to fragments.
(v. t.) To exchange for other money or currency of smaller denomination; as, to break a five dollar bill.
(v. t.) To destroy the strength, firmness, or consistency of; as, to break flax.
(v. t.) To weaken or impair, as health, spirit, or mind.
(v. t.) To diminish the force of; to lessen the shock of, as a fall or blow.
(v. t.) To impart, as news or information; to broach; -- with to, and often with a modified word implying some reserve; as, to break the news gently to the widow; to break a purpose cautiously to a friend.
(v. t.) To tame; to reduce to subjection; to make tractable; to discipline; as, to break a horse to the harness or saddle.
(v. t.) To destroy the financial credit of; to make bankrupt; to ruin.
(v. t.) To destroy the official character and standing of; to cashier; to dismiss.
(v. i.) To come apart or divide into two or more pieces, usually with suddenness and violence; to part; to burst asunder.
(v. i.) To open spontaneously, or by pressure from within, as a bubble, a tumor, a seed vessel, a bag.
(v. i.) To burst forth; to make its way; to come to view; to appear; to dawn.
(v. i.) To burst forth violently, as a storm.
(v. i.) To open up; to be scattered; to be dissipated; as, the clouds are breaking.
(v. i.) To become weakened in constitution or faculties; to lose health or strength.
(v. i.) To be crushed, or overwhelmed with sorrow or grief; as, my heart is breaking.
(v. i.) To make an abrupt or sudden change; to change the gait; as, to break into a run or gallop.
(v. i.) To fail in musical quality; as, a singer's voice breaks when it is strained beyond its compass and a tone or note is not completed, but degenerates into an unmusical sound instead. Also, to change in tone, as a boy's voice at puberty.
(v. i.) To fall out; to terminate friendship.
(v. t.) An opening made by fracture or disruption.
(v. t.) An interruption of continuity; change of direction; as, a break in a wall; a break in the deck of a ship.
(v. t.) A projection or recess from the face of a building.
(v. t.) An opening or displacement in the circuit, interrupting the electrical current.
(v. t.) An interruption; a pause; as, a break in friendship; a break in the conversation.
(v. t.) An interruption in continuity in writing or printing, as where there is an omission, an unfilled line, etc.
(v. t.) The first appearing, as of light in the morning; the dawn; as, the break of day; the break of dawn.
(v. t.) A large four-wheeled carriage, having a straight body and calash top, with the driver's seat in front and the footman's behind.
(v. t.) A device for checking motion, or for measuring friction. See Brake, n. 9 & 10.
(n.) See Commutator.
Example Sentences:
(1) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(2) They spend about 4.3 minutes of each working hour on a smoking break, the study shows.
(3) The mechanism by which pertussis toxin (PT) breaks the unresponsiveness of delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC) was examined in B10 mice.
(4) After absorption of labeled glucose, two pools of trehalose are found in dormant spores, one of which is extractable without breaking the spores, and the other, only after the spores are disintegrated.
(5) The following possible explanations were discussed: a) the tested psychotropic drugs block prostaglandin receptors in the stomach; b) the test substances react with prostaglandin in the nutritive solution; c) the substances stimulate metabolic processes in the stomach wall that break down prostaglandin.
(6) The ability of ligand to stimulate its own synthesis and that of its receptor suggests the presence of an autocrine positive feedback loop, however we were unable to break this loop in the breast cancer cells by antibodies that blocked the interaction of TGF alpha with the EGF receptor.
(7) Neutral sucrose density sedimentation patterns indicate that neutron-induced double strand-breaks sometimes occur in clusters of more than 100 in the same phage and that the effeciency with which double strand-breaks form is about 50 times that of gamma-induced double strand-breaks.
(8) Possible explanations of the clinical gains include 1) psychological encouragement, 2) improvements of mechanical efficiency, 3) restoration of cardiovascular fitness, thus breaking a vicous circle of dyspnoea, inactivity and worsening dyspnoea, 4) strengthening of the body musculature, thus reducing the proportion of anaerobic work, 5) biochemical adaptations reducing glycolysis in the active tissues, and 6) indirect responses to such factors as group support, with advice on smoking habits, breathing patterns and bronchial hygiene.
(9) At high luminances, the temporal, but not spatial, properties of this mechanism break down in a manner which had not been studied.Low-frequency inhibitory processThis process is manifest as a decrease in sensitivity from that of the simple excitatory process.
(10) These experiments represent the first occasion that the sequence specificity of a DNA damaging agent, which causes only double-strand breaks, has been determined to the exact base-pair in intact cells.
(11) The OPL first appears as a thin, discontinuous break in the cytoblast layer that is frequently interrupted by the profiles of migrating neuro- and glioblasts.
(12) Celebrity woodlanders Tax breaks and tree-hugging already draw the wealthy and well-known to buy British forests.
(13) But we need politicians to break out of historical routines.
(14) For Burroughs, who had been publishing ground-breaking books for 20 years without much appreciable financial return, it was association with fame and the music industry, as well as the possible benefits: a wider readership, film hook-ups and more money.
(15) Once you've invested many years in a career, figuring out how to take time out and then return to a role that's comparable to the one you left (or as comparable as you want it to be) requires more than confidence and enthusiasm - employers need to actively acknowledge the benefits of such breaks and be more receptive to those seeking to return”.
(16) A dose-dependent increase in chromatid lesions, i.e., achromatic lesions, chromatid breaks, chromatid deletions and triradial or quandriradial chromosomal exchange fiqures, was found.
(17) From the stress-strain curve the following values were selected: strain, stress, and slope at 80 mmHg equivalent pressure (1 mmHg = 133.3 Pa); maximum stress, strain, and slope; and breaking stress, strain, and slope if the sample broke.
(18) Everyone worked hard, but it is fair to pick out Willian because of his work-rate, quality on the ball, participation in the first goal and quality of the second.” It had been Willian’s fizzed cross, 11 minutes before the break, which Dragovic had nodded inadvertently inside Shovkovskiy’s near post to earn the hosts their initial lead.
(19) The possibility that mammalian DNA topoisomerase II is an intracellular target which mediates drug-induced DNA breaks is supported by the following studies using 4'-(9-acridinylamino)methane-sulfon-m-anisidide (m-AMSA): (a) a single m-AMSA-dependent DNA cleavage activity copurified with calf thymus DNA topoisomerase II activity at all chromatographic steps of the enzyme purification; (b) m-AMSA-induced DNA cleavage by this purified activity resulted in the covalent attachment of protein to the 5'-ends of the DNA via a tyrosyl phosphate bond.
(20) The authorities had said they used water cannon, teargas and smoke grenades to break up the protest.
Bridge
Definition:
(n.) A structure, usually of wood, stone, brick, or iron, erected over a river or other water course, or over a chasm, railroad, etc., to make a passageway from one bank to the other.
(n.) Anything supported at the ends, which serves to keep some other thing from resting upon the object spanned, as in engraving, watchmaking, etc., or which forms a platform or staging over which something passes or is conveyed.
(n.) The small arch or bar at right angles to the strings of a violin, guitar, etc., serving of raise them and transmit their vibrations to the body of the instrument.
(n.) A device to measure the resistance of a wire or other conductor forming part of an electric circuit.
(n.) A low wall or vertical partition in the fire chamber of a furnace, for deflecting flame, etc.; -- usually called a bridge wall.
(v. t.) To build a bridge or bridges on or over; as, to bridge a river.
(v. t.) To open or make a passage, as by a bridge.
(v. t.) To find a way of getting over, as a difficulty; -- generally with over.
Example Sentences:
(1) The role of Ca2+ in cell agglutination may be either to activate the cell-surface dextran receptor or to form specific intercellular Ca2+ bridges.
(2) Data from cases with myocardial bridges show that both fatty streaks and raised lesions are seldom observed in the region distal to myocardial bridge.
(3) which suggest that ~60-90% of the cross-bridges attached in rigor are attached in relaxed fibers at an ionic strength of 20 mM and ~2-10% of this number of cross-bridges are attached in a relaxed fiber at an ionic strength of 170 mM.
(4) Terry Waite Chair, Benedict Birnberg Deputy chair, Antonio Ferrara CEO The Prisons Video Trust • If I want to build a bridge, I call in a firm of civil engineers who specialise in bridge-building.
(5) Brief digestion at neutral pH without reduction produced a molecule in which the Fab and Fc fragments were still linked by a pair of labile disulphide bridges, and the Fc fragment released by cleaving these bonds, called 1Fc fragment, contained a portion of the ;hinge' region including an interchain disulphide bridge.
(6) Acute coronary angiography showed myocardial bridging and total occlusion of the left anterior descending artery in the middle one-third of its course.
(7) These force-generators are identified with projections (cross-bridges) on the thick filament, each consisting of part of a myosin molecule.
(8) Segmental function was diminished an average of 67.8% in "noses" and 46.6% in "bridges".
(9) Gibbs was sent off in the first half at Stamford Bridge for handball, despite replays clearly showing it was his team-mate Alex Oxlade-Chamberlain who illegally deflected an Eden Hazard shot.
(10) Close van der Waals' contacts between the Cys22-Cys63 and Cys51-Cys75 disulfide bridges and the central hydrophobic core composed of the Trp25, Leu46, His48a and Trp62 side-chains are among the distinguishing features of the kringle 2 fold.
(11) The reactivity of the three disulphide bridges of insulin towards sodium sulphite was studied by amperometric titration of the liberated thiol groups.
(12) The cartilage of the concha is a valuable substitute of the bridge and the posterior wall of the external auditory conduct.
(13) It is shown from an analysis of the transient force responses observed after sudden changes in muscle length applied both at full and reduced overlap and during the rising phase of short tetani that these responses can be explained on the basis of varying numbers of cross bridges attached at the time of the length step.
(14) A two-lane, 400m bridge – funded by Jica, Japan's aid agency – coupled with simplified procedures agreed by Zambia and Zimbabwe have speeded up processing time.
(15) The dynamic properties of cross-bridge movement were investigated in glycerol-treated muscle fibers under various conditions by analyzing tension responses to two types of length change.
(16) The first problem facing Calderdale is sheep-rustling Happy Valley – filmed around Hebden Bridge, with its beautiful stone houses straight off the pages of the Guardian’s Lets Move To – may be filled with rolling hills and verdant pastures, but the reality of rural issues are harsh.
(17) It is suggested that a general manner of folding may be a common feature of the heterogeneous population of kappa-chains: one bridge which folds an invariable stretch of the chain, another bridge which folds a stretch that varies from protein to protein, and a bridge at the C-terminus which is the interchain link.
(18) 1-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3- nitrosourea hydrochloride (ACNU) causes chloroethylation of DNA strand followed by cross linking through an ethylene bridge.
(19) Optimal staining of antigen rich tissue, such as frozen sections, with the peroxidase antiperoxidase method required low antiserum concentrations apparently to minimize the binding of both antigen-binding fragments of the bridging antibody to the tissue bound antiserum.
(20) The results provided information on the energetics of actin-myosin-ligand states that occur in the portion of the cross-bridge cycle where MgATP binds to myosin.