(v. t.) To strain apart; to sever by fracture; to divide with violence; as, to break a rope or chain; to break a seal; to break an axle; to break rocks or coal; to break a lock.
(v. t.) To lay open as by breaking; to divide; as, to break a package of goods.
(v. t.) To lay open, as a purpose; to disclose, divulge, or communicate.
(v. t.) To infringe or violate, as an obligation, law, or promise.
(v. t.) To interrupt; to destroy the continuity of; to dissolve or terminate; as, to break silence; to break one's sleep; to break one's journey.
(v. t.) To destroy the completeness of; to remove a part from; as, to break a set.
(v. t.) To destroy the arrangement of; to throw into disorder; to pierce; as, the cavalry were not able to break the British squares.
(v. t.) To shatter to pieces; to reduce to fragments.
(v. t.) To exchange for other money or currency of smaller denomination; as, to break a five dollar bill.
(v. t.) To destroy the strength, firmness, or consistency of; as, to break flax.
(v. t.) To weaken or impair, as health, spirit, or mind.
(v. t.) To diminish the force of; to lessen the shock of, as a fall or blow.
(v. t.) To impart, as news or information; to broach; -- with to, and often with a modified word implying some reserve; as, to break the news gently to the widow; to break a purpose cautiously to a friend.
(v. t.) To tame; to reduce to subjection; to make tractable; to discipline; as, to break a horse to the harness or saddle.
(v. t.) To destroy the financial credit of; to make bankrupt; to ruin.
(v. t.) To destroy the official character and standing of; to cashier; to dismiss.
(v. i.) To come apart or divide into two or more pieces, usually with suddenness and violence; to part; to burst asunder.
(v. i.) To open spontaneously, or by pressure from within, as a bubble, a tumor, a seed vessel, a bag.
(v. i.) To burst forth; to make its way; to come to view; to appear; to dawn.
(v. i.) To burst forth violently, as a storm.
(v. i.) To open up; to be scattered; to be dissipated; as, the clouds are breaking.
(v. i.) To become weakened in constitution or faculties; to lose health or strength.
(v. i.) To be crushed, or overwhelmed with sorrow or grief; as, my heart is breaking.
(v. i.) To make an abrupt or sudden change; to change the gait; as, to break into a run or gallop.
(v. i.) To fail in musical quality; as, a singer's voice breaks when it is strained beyond its compass and a tone or note is not completed, but degenerates into an unmusical sound instead. Also, to change in tone, as a boy's voice at puberty.
(v. i.) To fall out; to terminate friendship.
(v. t.) An opening made by fracture or disruption.
(v. t.) An interruption of continuity; change of direction; as, a break in a wall; a break in the deck of a ship.
(v. t.) A projection or recess from the face of a building.
(v. t.) An opening or displacement in the circuit, interrupting the electrical current.
(v. t.) An interruption; a pause; as, a break in friendship; a break in the conversation.
(v. t.) An interruption in continuity in writing or printing, as where there is an omission, an unfilled line, etc.
(v. t.) The first appearing, as of light in the morning; the dawn; as, the break of day; the break of dawn.
(v. t.) A large four-wheeled carriage, having a straight body and calash top, with the driver's seat in front and the footman's behind.
(v. t.) A device for checking motion, or for measuring friction. See Brake, n. 9 & 10.
(n.) See Commutator.
Example Sentences:
(1) Lucy and Ed will combine coverage of hard and breaking news with a commitment to investigative journalism, which their track record so clearly demonstrates”.
(2) They spend about 4.3 minutes of each working hour on a smoking break, the study shows.
(3) The mechanism by which pertussis toxin (PT) breaks the unresponsiveness of delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC) was examined in B10 mice.
(4) After absorption of labeled glucose, two pools of trehalose are found in dormant spores, one of which is extractable without breaking the spores, and the other, only after the spores are disintegrated.
(5) The following possible explanations were discussed: a) the tested psychotropic drugs block prostaglandin receptors in the stomach; b) the test substances react with prostaglandin in the nutritive solution; c) the substances stimulate metabolic processes in the stomach wall that break down prostaglandin.
(6) The ability of ligand to stimulate its own synthesis and that of its receptor suggests the presence of an autocrine positive feedback loop, however we were unable to break this loop in the breast cancer cells by antibodies that blocked the interaction of TGF alpha with the EGF receptor.
(7) Neutral sucrose density sedimentation patterns indicate that neutron-induced double strand-breaks sometimes occur in clusters of more than 100 in the same phage and that the effeciency with which double strand-breaks form is about 50 times that of gamma-induced double strand-breaks.
(8) Possible explanations of the clinical gains include 1) psychological encouragement, 2) improvements of mechanical efficiency, 3) restoration of cardiovascular fitness, thus breaking a vicous circle of dyspnoea, inactivity and worsening dyspnoea, 4) strengthening of the body musculature, thus reducing the proportion of anaerobic work, 5) biochemical adaptations reducing glycolysis in the active tissues, and 6) indirect responses to such factors as group support, with advice on smoking habits, breathing patterns and bronchial hygiene.
(9) At high luminances, the temporal, but not spatial, properties of this mechanism break down in a manner which had not been studied.Low-frequency inhibitory processThis process is manifest as a decrease in sensitivity from that of the simple excitatory process.
(10) These experiments represent the first occasion that the sequence specificity of a DNA damaging agent, which causes only double-strand breaks, has been determined to the exact base-pair in intact cells.
(11) The OPL first appears as a thin, discontinuous break in the cytoblast layer that is frequently interrupted by the profiles of migrating neuro- and glioblasts.
(12) Celebrity woodlanders Tax breaks and tree-hugging already draw the wealthy and well-known to buy British forests.
(13) But we need politicians to break out of historical routines.
(14) For Burroughs, who had been publishing ground-breaking books for 20 years without much appreciable financial return, it was association with fame and the music industry, as well as the possible benefits: a wider readership, film hook-ups and more money.
(15) Once you've invested many years in a career, figuring out how to take time out and then return to a role that's comparable to the one you left (or as comparable as you want it to be) requires more than confidence and enthusiasm - employers need to actively acknowledge the benefits of such breaks and be more receptive to those seeking to return”.
(16) A dose-dependent increase in chromatid lesions, i.e., achromatic lesions, chromatid breaks, chromatid deletions and triradial or quandriradial chromosomal exchange fiqures, was found.
(17) From the stress-strain curve the following values were selected: strain, stress, and slope at 80 mmHg equivalent pressure (1 mmHg = 133.3 Pa); maximum stress, strain, and slope; and breaking stress, strain, and slope if the sample broke.
(18) Everyone worked hard, but it is fair to pick out Willian because of his work-rate, quality on the ball, participation in the first goal and quality of the second.” It had been Willian’s fizzed cross, 11 minutes before the break, which Dragovic had nodded inadvertently inside Shovkovskiy’s near post to earn the hosts their initial lead.
(19) The possibility that mammalian DNA topoisomerase II is an intracellular target which mediates drug-induced DNA breaks is supported by the following studies using 4'-(9-acridinylamino)methane-sulfon-m-anisidide (m-AMSA): (a) a single m-AMSA-dependent DNA cleavage activity copurified with calf thymus DNA topoisomerase II activity at all chromatographic steps of the enzyme purification; (b) m-AMSA-induced DNA cleavage by this purified activity resulted in the covalent attachment of protein to the 5'-ends of the DNA via a tyrosyl phosphate bond.
(20) The authorities had said they used water cannon, teargas and smoke grenades to break up the protest.
Design
Definition:
(n.) To draw preliminary outline or main features of; to sketch for a pattern or model; to delineate; to trace out; to draw.
(n.) To mark out and exhibit; to designate; to indicate; to show; to point out; to appoint.
(n.) To create or produce, as a work of art; to form a plan or scheme of; to form in idea; to invent; to project; to lay out in the mind; as, a man designs an essay, a poem, a statue, or a cathedral.
(n.) To intend or purpose; -- usually with for before the remote object, but sometimes with to.
(v. i.) To form a design or designs; to plan.
(n.) A preliminary sketch; an outline or pattern of the main features of something to be executed, as of a picture, a building, or a decoration; a delineation; a plan.
(n.) A plan or scheme formed in the mind of something to be done; preliminary conception; idea intended to be expressed in a visible form or carried into action; intention; purpose; -- often used in a bad sense for evil intention or purpose; scheme; plot.
(n.) Specifically, intention or purpose as revealed or inferred from the adaptation of means to an end; as, the argument from design.
(n.) The realization of an inventive or decorative plan; esp., a work of decorative art considered as a new creation; conception or plan shown in completed work; as, this carved panel is a fine design, or of a fine design.
(n.) The invention and conduct of the subject; the disposition of every part, and the general order of the whole.
Example Sentences:
(1) Questionnaires were used and the respondent self-designation method measured leadership.
(2) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(3) Until his return to Brazil in 1985, Niemeyer worked in Israel, France and north Africa, designing among other buildings the University of Haifa on Mount Carmel; the campus of Constantine University in Algeria (now known as Mentouri University); the offices of the French Communist party and their newspaper l'Humanité in Paris; and the ministry of external relations and the cathedral in Brasilia.
(4) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(5) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(6) This study was designed to investigate the localization and cyclic regulation of the mRNA for these two IGFBPs in the porcine ovary, RNA was extracted from whole ovaries morphologically classified as immature, preovulatory, and luteal.
(7) As important providers of health care education, nurses need to be fully informed of the research findings relevant to effective interventions designed to motivate health-related behavior change.
(8) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(9) According to the finite element analysis, the design bases of fixed restorations applied in the teeth accompanied with the absorption of the alveolar bone were preferred.
(10) These clones, designated as TcHMC-2, showed strong cytotoxicity against both HMC-2 and K562 cells.
(11) By the 1860s, French designs were using larger front wheels and steel frames, which although lighter were more rigid, leading to its nickname of “boneshaker”.
(12) In a double-blind, crossover-designed study, 9 male subjects (age range: 18-25 years) received 25 mg orally, four times per day of either S or an identically-appearing placebo (P) 2 d prior to and during HA.
(13) "The proposed 'reform' is designed to legitimise this blatantly unfair, police state practice, while leaving the rest of the criminal procedure law as misleading decoration," said Professor Jerome Cohen, an expert on China at New York University's School of Law.
(14) Though the 54-year-old designer made brief returns to the limelight after his fall from grace, designing a one-off collection for Oscar de la Renta last year , his appointment at Margiela marks a more permanent comeback.
(15) What we’re doing is designed to improve people’s lives.” "I don't see race, colour or creed, and neither do my children," he added.
(16) This study was designed to examine the effect of the storage configuration of skin and the ratio of tissue-to-storage medium on the viability of skin stored under refrigeration.
(17) However, each of the studies had numerous methodological flaws which biased their results against finding a relationship: either their outcome measures had questionable validity, their research designs were inappropriate, or the statistical analyses were poorly conceived.
(18) Methods to minimize bias in the design and implementation of consultation-liaison research are suggested.
(19) To distinguish the various types, we designated the 90 kd types from CBA and AKR mice C6A1 and C6A2, respectively, and the corresponding 100 kd types C6B1 and C6B2, respectively.
(20) Knapman concluded that the 40-year-old designer, whose full name was Lee Alexander McQueen, "killed himself while the balance of his mind was disturbed".