(n.) The act of breaking; a break; a breaking; also, articles broken.
(n.) An allowance or compensation for things broken accidentally, as in transportation or use.
Example Sentences:
(1) Cytosolic-to-mitochondrial ratios from maximal initial rates after correction for mitochondrial breakage were increased above controls in diabetic hearts for nucleoside diphosphokinase and aspartate aminotransferase.
(2) Comparison of germline and translocation clones demonstrated that breakage of chromosome 1 had occurred at the border of a tandem repeat of Alu sequences.
(3) These findings of enhanced breakage by FUdR exposure in vitro, nevertheless, may suggest that leukemic cells in general are more susceptible to breakage than normal cells, thereby predisposing the former to secondary chromosome rearrangements.
(4) In contrast to the photosensitivity of ribosome-bound 16S rRNA toward chain breakage, free 16S rRNA seems to be resistant toward photoinduced chain breakage at doses of incident 253.7-nm radiation up to at least 10(21) quanta.
(5) The stamps, which were similar in paper and size to Japanese 10-yen postage stamps, were wrapped around the penis before sleep and the stamp ring was checked for breakage the next morning.
(6) The criteria of failure of pedicular instrumentation or "death" of an implant were defined as 1) screw bending, 2) screw breakage, 3) infection, 4) loosening of implants, 5) any rod or plate hardware problems, or 6) removal of hardware due to a neurologic complication.
(7) The depletion of NAD by CC-1065 was blocked by 3-aminobenzamide, which is consistent with a NAD depletion mechanism involving poly-(ADP-ribose) synthesis in response to a repair-induced DNA strand breakage event.
(8) The action of lysozyme on isolated cell walls released some free reducing groups, indicating limited breakage of the polysaccharide chains of peptidoglycan, and it was concluded that lysozyme modified the peptidoglycan and made it more susceptible to autolysin(s).
(9) Our data support the postulate that chromatin primary structure plays a role in modulating carcinogen damage to chromosomal macromolecules and in DNA strand breakage and repair mechanisms.
(10) Both human and hen lysozymes were equally effective in chain breakage of S. mutans DPR and S. mutans DJR.
(11) We conclude from our analysis that the mechanisms of DNA joining are not locus or location specific, but at least a portion of the mechanisms of chromosomal breakages do show locus specificity.
(12) When copies of this sequence were cloned and analyzed, they were found in all cases to be located at or very near sites of breakage.
(13) Usherwood's account of the breakage of Palmer's diathermy forceps (June 30, p. 773).
(14) Monosomy, translocation, and breakage of chromosome 5 involving band 5q31 and monosomy and partial deletion of chromosome 6 involving band 6q22-q24 were independently observed in primary tumor cells from three of four tumors examined.
(15) The detected shifts lead to disturbance of T-B-cell cooperation, antibody genesis, and breakage of fibrinolysis immune regulation which determine progression of inflammatory changes in the bronchopulmonary system.
(16) Most chromosome rearrangements occurred after breakage in constitutive heterochromatin, and no recurrent breakpoints were found in euchromatin except 11p15.
(17) Our method to break glomeruli is inexpensive and less time-consuming than the breakage with ultrasonic vibration.
(18) The mechanical performance of these sutures was judged by the following parameters: knot breakage force, configuration of secure knots, and knot run down force.
(19) A nondisjunction and chromosome breakage screening system devised by Craymer and modified in our laboratory, involves an X;Y translocation with the short arm of the Y (Ys), marked with the wild type allele of yellow, attached to the distal end of an X (break point 11D) carrying the recessive marker y; and the long arm of the Y chromosome (YL), marked with the dominant locus Bar of Stone (BS), attached to the proximal end of the X.
(20) We have previously shown that blockade of the Na+,K(+)-pump by the cardiac glycoside ouabain produces doxorubicin resistance and decreases topoisomerase II-mediated DNA strand breakage in hamster cells.
Breakdown
Definition:
(n.) The act or result of breaking down, as of a carriage; downfall.
(n.) A noisy, rapid, shuffling dance engaged in competitively by a number of persons or pairs in succession, as among the colored people of the Southern United States, and so called, perhaps, because the exercise is continued until most of those who take part in it break down.
(n.) Any rude, noisy dance performed by shuffling the feet, usually by one person at a time.
Example Sentences:
(1) Because the mitogenic action of IL 2 resembles that of some growth factors, the possible role of phosphatidylinositol breakdown in the activation of T cells by IL 2 was examined.
(2) It is also becoming apparent that effects of insulin and other acute regulatory agents on muscle breakdown are limited to nonmyofibrillar components.
(3) The coronary vasodilator adenosine can be formed in the heart by breakdown of AMP or S-adenosylhomocysteine (SAdoHcy).
(4) Post-operative levels of C3 breakdown products were significantly higher in atheromatic patients than in controls, most likely due to the insertion of dacron arterial prostheses in the first group.
(5) F(ab')2 anti-Ig stimulates the rapid breakdown of inositol phospholipids in B cells, resulting in the prolonged release of inositol (poly)phosphates and diacylglycerol.
(6) The kinetics of the luminescent signal with the different luciferin esters varied significantly, indicating possible differences in the rates of uptake, breakdown and enzyme inhibition.
(7) The muscle-protein breakdown is sustained and the released amino acids are taken up by the liver and other RE structures where they are used as substrates for energy and for synthesis of defense-related proteins.
(8) At follow-up, the initial presence of signs of repression was significantly more common in such initially nonregressive patients as had escaped a later psychotic breakdown.
(9) Third, an indirect activation of protein kinase C may occur via an increase in the rate of phosphoinositide breakdown.
(10) The response is dose dependent for LPA concentrations from 10(-8) to 10(-3) M. Incubation of oocytes in LPA does not induce germinal vesicle breakdown.
(11) The breakdown of systemic fibrinogen may be important because of the anticoagulant effect this can produce.
(12) The breakdown of homocysteine, via the transsulphuration pathway, was augmented by Zn deficiency.
(13) Parallel sections were analyzed for possible parenchymal changes associated with the BBB breakdown.
(14) The breakdown of answers to both questions revealed a significant partisan divide depending on people’s voting intention, with Labor supporters much more likely than Coalition backers to see the commission as a political attack and Heydon as conflicted.
(15) The commonest finding is a slight to moderate breakdown of BCB function without evidence of intrathecal immunoglobulin synthesis.
(16) HOE was the most active compound, being able to accelerate PIP2 breakdown at concentrations between 10(-12) and 10(-6) M, while in the case of HEE the effective doses ranged from 10(-11) to 10(-7) M and from 10(-9) to 10(-6) M in the case of HNE.
(17) The critical membrane potential difference for breakdown is therefore pulse-length independent.
(18) Della Roe, Dhu’s mother, said the loss of her daughter had triggered an emotional breakdown.
(19) With ribosomes the pH optimum of proteolytic breakdown is at about 7.
(20) The findings link terminal breakdown of the blood-brain barrier and extensive viral antigen expression in CSF leukocytes with experimental CDV infection resulting in death.