What's the difference between breakdown and defect?

Breakdown


Definition:

  • (n.) The act or result of breaking down, as of a carriage; downfall.
  • (n.) A noisy, rapid, shuffling dance engaged in competitively by a number of persons or pairs in succession, as among the colored people of the Southern United States, and so called, perhaps, because the exercise is continued until most of those who take part in it break down.
  • (n.) Any rude, noisy dance performed by shuffling the feet, usually by one person at a time.

Example Sentences:

  • (1) Because the mitogenic action of IL 2 resembles that of some growth factors, the possible role of phosphatidylinositol breakdown in the activation of T cells by IL 2 was examined.
  • (2) It is also becoming apparent that effects of insulin and other acute regulatory agents on muscle breakdown are limited to nonmyofibrillar components.
  • (3) The coronary vasodilator adenosine can be formed in the heart by breakdown of AMP or S-adenosylhomocysteine (SAdoHcy).
  • (4) Post-operative levels of C3 breakdown products were significantly higher in atheromatic patients than in controls, most likely due to the insertion of dacron arterial prostheses in the first group.
  • (5) F(ab')2 anti-Ig stimulates the rapid breakdown of inositol phospholipids in B cells, resulting in the prolonged release of inositol (poly)phosphates and diacylglycerol.
  • (6) The kinetics of the luminescent signal with the different luciferin esters varied significantly, indicating possible differences in the rates of uptake, breakdown and enzyme inhibition.
  • (7) The muscle-protein breakdown is sustained and the released amino acids are taken up by the liver and other RE structures where they are used as substrates for energy and for synthesis of defense-related proteins.
  • (8) At follow-up, the initial presence of signs of repression was significantly more common in such initially nonregressive patients as had escaped a later psychotic breakdown.
  • (9) Third, an indirect activation of protein kinase C may occur via an increase in the rate of phosphoinositide breakdown.
  • (10) The response is dose dependent for LPA concentrations from 10(-8) to 10(-3) M. Incubation of oocytes in LPA does not induce germinal vesicle breakdown.
  • (11) The breakdown of systemic fibrinogen may be important because of the anticoagulant effect this can produce.
  • (12) The breakdown of homocysteine, via the transsulphuration pathway, was augmented by Zn deficiency.
  • (13) Parallel sections were analyzed for possible parenchymal changes associated with the BBB breakdown.
  • (14) The breakdown of answers to both questions revealed a significant partisan divide depending on people’s voting intention, with Labor supporters much more likely than Coalition backers to see the commission as a political attack and Heydon as conflicted.
  • (15) The commonest finding is a slight to moderate breakdown of BCB function without evidence of intrathecal immunoglobulin synthesis.
  • (16) HOE was the most active compound, being able to accelerate PIP2 breakdown at concentrations between 10(-12) and 10(-6) M, while in the case of HEE the effective doses ranged from 10(-11) to 10(-7) M and from 10(-9) to 10(-6) M in the case of HNE.
  • (17) The critical membrane potential difference for breakdown is therefore pulse-length independent.
  • (18) Della Roe, Dhu’s mother, said the loss of her daughter had triggered an emotional breakdown.
  • (19) With ribosomes the pH optimum of proteolytic breakdown is at about 7.
  • (20) The findings link terminal breakdown of the blood-brain barrier and extensive viral antigen expression in CSF leukocytes with experimental CDV infection resulting in death.

Defect


Definition:

  • (n.) Want or absence of something necessary for completeness or perfection; deficiency; -- opposed to superfluity.
  • (n.) Failing; fault; imperfection, whether physical or moral; blemish; as, a defect in the ear or eye; a defect in timber or iron; a defect of memory or judgment.
  • (v. i.) To fail; to become deficient.
  • (v. t.) To injure; to damage.

Example Sentences:

  • (1) We have cloned the phr gene that encodes DNA photolyase from Salmonella typhimurium by in vivo complementation of Escherichia coli phr gene defect.
  • (2) Cor triatriatum (CT) is a rare congenital defect, surgically correctable, and sometimes difficult to diagnose by cardiac catheterization.
  • (3) Sixteen patients (27%) manifested anomalies of the urinary tract: 12 had markedly altered kidneys, 8 of which were unilateral and ipsilateral to the diaphragmatic defect.
  • (4) Furthermore echography revealed a collateral subperiosteal edema and a moderate thickening of extraocular muscles and bone periostitis, a massive swelling of muscles and bone defects in subperiosteal abscesses as well as encapsulated abscesses of the orbit and a concomitant retrobulbar neuritis in orbital cellulitis.
  • (5) Seven males have been observed carrying both inherited tritan and red-green defects.
  • (6) Mechanisms by which a defect in the synthesis of dolichol-oligosaccharides might alter the degree of beta-1,6 branching in N-linked carbohydrates are discussed.
  • (7) Both Types I and II collagen are important constituents of the affected tissues, and thus defective collagens are reasonable candidates for the primary abnormality in adolescent idiopathic scoliosis (AIS).
  • (8) Ventricular septal defect types were perimembranous (six), malalignment (seven), supracristal (three), midmuscular (one), and inlet (one).
  • (9) Defects of several membrane proteins were found with sodium dodecyl sulfate--polyacrylamide gel electrophoresis.
  • (10) After early repair of congenital cardiovascular defects, such as coarctation of the aorta, late stenosis may become a problem.
  • (11) The association of these defects of teeth and bone was found to be transmitted as an autosomal dominant trait over four generations.
  • (12) They presented their clinical observations on 4 brothers from the 'G Family' who shared a constellation of findings with a generalised tendency to midline defects.
  • (13) Distant ischemia was distinguished from peri-infarctional ischemia by the presence of transient thallium defects in, or slow thallium washout from myocardium not supplied by the infarct-related coronary artery.
  • (14) A distally based posterior tibial artery adipofascial flap with skin graft was used for the reconstruction of soft tissue defects over the Achilles tendon in three cases and over the heel in three cases.
  • (15) In the case with a more distally situated VSD, the bundle branches skirted the anterior and distal walls of the defect.
  • (16) Both models showed the expected wound-healing defects of the diabetic rats.
  • (17) Intercistronic complementation of these mutants with pm1493 and dl121, two SV40 mutants that are defective in agnoprotein but encode wild-type T antigen, results in an increased synthesis of agnoprotein in the infected cells.
  • (18) Cells defective in gpa2 fail to produce cAMP in response to glucose stimulation.
  • (19) Moloney murine sarcoma virus ts110 possesses a thermosensitive splicing defect.
  • (20) This paper reports on observations of five families suffering from distinct thrombophilia due to a protein C defect.