(n.) The act or result of breaking down, as of a carriage; downfall.
(n.) A noisy, rapid, shuffling dance engaged in competitively by a number of persons or pairs in succession, as among the colored people of the Southern United States, and so called, perhaps, because the exercise is continued until most of those who take part in it break down.
(n.) Any rude, noisy dance performed by shuffling the feet, usually by one person at a time.
Example Sentences:
(1) Because the mitogenic action of IL 2 resembles that of some growth factors, the possible role of phosphatidylinositol breakdown in the activation of T cells by IL 2 was examined.
(2) It is also becoming apparent that effects of insulin and other acute regulatory agents on muscle breakdown are limited to nonmyofibrillar components.
(3) The coronary vasodilator adenosine can be formed in the heart by breakdown of AMP or S-adenosylhomocysteine (SAdoHcy).
(4) Post-operative levels of C3 breakdown products were significantly higher in atheromatic patients than in controls, most likely due to the insertion of dacron arterial prostheses in the first group.
(5) F(ab')2 anti-Ig stimulates the rapid breakdown of inositol phospholipids in B cells, resulting in the prolonged release of inositol (poly)phosphates and diacylglycerol.
(6) The kinetics of the luminescent signal with the different luciferin esters varied significantly, indicating possible differences in the rates of uptake, breakdown and enzyme inhibition.
(7) The muscle-protein breakdown is sustained and the released amino acids are taken up by the liver and other RE structures where they are used as substrates for energy and for synthesis of defense-related proteins.
(8) At follow-up, the initial presence of signs of repression was significantly more common in such initially nonregressive patients as had escaped a later psychotic breakdown.
(9) Third, an indirect activation of protein kinase C may occur via an increase in the rate of phosphoinositide breakdown.
(10) The response is dose dependent for LPA concentrations from 10(-8) to 10(-3) M. Incubation of oocytes in LPA does not induce germinal vesicle breakdown.
(11) The breakdown of systemic fibrinogen may be important because of the anticoagulant effect this can produce.
(12) The breakdown of homocysteine, via the transsulphuration pathway, was augmented by Zn deficiency.
(13) Parallel sections were analyzed for possible parenchymal changes associated with the BBB breakdown.
(14) The breakdown of answers to both questions revealed a significant partisan divide depending on people’s voting intention, with Labor supporters much more likely than Coalition backers to see the commission as a political attack and Heydon as conflicted.
(15) The commonest finding is a slight to moderate breakdown of BCB function without evidence of intrathecal immunoglobulin synthesis.
(16) HOE was the most active compound, being able to accelerate PIP2 breakdown at concentrations between 10(-12) and 10(-6) M, while in the case of HEE the effective doses ranged from 10(-11) to 10(-7) M and from 10(-9) to 10(-6) M in the case of HNE.
(17) The critical membrane potential difference for breakdown is therefore pulse-length independent.
(18) Della Roe, Dhu’s mother, said the loss of her daughter had triggered an emotional breakdown.
(19) With ribosomes the pH optimum of proteolytic breakdown is at about 7.
(20) The findings link terminal breakdown of the blood-brain barrier and extensive viral antigen expression in CSF leukocytes with experimental CDV infection resulting in death.
Degradation
Definition:
(n.) The act of reducing in rank, character, or reputation, or of abasing; a lowering from one's standing or rank in office or society; diminution; as, the degradation of a peer, a knight, a general, or a bishop.
(n.) The state of being reduced in rank, character, or reputation; baseness; moral, physical, or intellectual degeneracy; disgrace; abasement; debasement.
(n.) Diminution or reduction of strength, efficacy, or value; degeneration; deterioration.
(n.) A gradual wearing down or wasting, as of rocks and banks, by the action of water, frost etc.
(n.) The state or condition of a species or group which exhibits degraded forms; degeneration.
(n.) Arrest of development, or degeneration of any organ, or of the body as a whole.
Example Sentences:
(1) This bone could not be degraded by human monocytes in vitro as well as control bone (only 54% of control; P less than 0.003).
(2) Lp(a) also complexes to plasmin-fibrinogen digests, and binding increases in proportion to the time of plasmin-induced fibrinogen degradation.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) At the highest dose of chloroquine tested (500 microM), a slightly greater increase in insulin binding and a decrease in insulin degradation were observed in fetal cells as compared with adult cells.
(5) Addition of extracellular mevalonate led to a concentration-dependent fall in both processes, although a higher concentration was required to produce the same effect on LDL degradation as on HMG-CoA reductase activity.
(6) Radioiodinated a-factor was used to identify the a-factor-degrading activity, which is cell associated, endoproteolytic, and not required for response to pheromone.
(7) Densitometric analysis of myofibrillar proteins separated with sodium dodecyl sulfate-polyacrylamide gel electrophoresis indicated that troponin I and troponin T were degraded during 60 minutes of CGI.
(8) In addition, we found apyrase activity (which degrades ATP and ADP to AMP and orthophosphate) and an anticoagulant.
(9) Degradation of both viral and host DNA with micrococcal nuclease and spleen phosphodiesterase indicated that CdG was incorporated primarily into internal positions in both DNAs.
(10) In vitro studies showed that BOF-A2 was rapidly degraded to EM-FU and CNDP in homogenates of the liver and small intestine of mice and rats, and in sera of mice, rats and human, and the conversion of EM-FU to 5-FU occurred only in the microsomal fraction of rat liver in the presence of NADPH.
(11) Only PPACK completely inhibited changes in fibrin degradation products, plasminogen and alpha 2-antiplasmin.
(12) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
(13) When cultures were pulse labeled for 15 min and then incubated under chase conditions for 105 min, the amount of degraded collagen attained a value equal to approximately 20% of the amount synthesized during the labeling period; the data were fit with a simple exponential function that had a 40-min rise time and a 12-min lag time.
(14) The mode of ribosome degradation under this condition is discussed in terms of differential appearance of these intermediate particles.
(15) Degraded visual acuity had a significant effect on cadence, foot placement, and foot clearance, but visual surround conditions did not.
(16) The resistance of GSA 65 to proteolytic degradation, together with previous immunofluorescence data that indicate the antigen is an integral part of the G. lamblia cyst wall, suggests that this molecule may play a role in maintaining the integrity of the cyst in vivo.
(17) 5% of the degradation resulted from enzymatic activity in the culture medium, presumably due to secretion of proteolytic enzymes by the cells.
(18) At 37 degrees C, 125I-labeled TNF-alpha was rapidly internalized and degraded in L-929, U-937 and LAK cells.
(19) Recovery after EEDQ administration showed that both receptor production rate and degradation rate constants of anterior pituitary D2 and striatal D1 receptors were slowed after chronic estradiol treatment, whereas recovery rates for striatal D2 dopamine receptors were unaffected.
(20) The specific rates of degradation of L-arginine-AMC, gly-proline-AMC, N-alpha-benzoyl-L-arginine-AMC and N-[p-toluene-sulphonyl]gly-pro-arginine-AMC were significantly greater in that group, indicating that the composition of their gingival crevicular fluid was different from that of the gingivitis group.