What's the difference between bridge and chain?

Bridge


Definition:

  • (n.) A structure, usually of wood, stone, brick, or iron, erected over a river or other water course, or over a chasm, railroad, etc., to make a passageway from one bank to the other.
  • (n.) Anything supported at the ends, which serves to keep some other thing from resting upon the object spanned, as in engraving, watchmaking, etc., or which forms a platform or staging over which something passes or is conveyed.
  • (n.) The small arch or bar at right angles to the strings of a violin, guitar, etc., serving of raise them and transmit their vibrations to the body of the instrument.
  • (n.) A device to measure the resistance of a wire or other conductor forming part of an electric circuit.
  • (n.) A low wall or vertical partition in the fire chamber of a furnace, for deflecting flame, etc.; -- usually called a bridge wall.
  • (v. t.) To build a bridge or bridges on or over; as, to bridge a river.
  • (v. t.) To open or make a passage, as by a bridge.
  • (v. t.) To find a way of getting over, as a difficulty; -- generally with over.

Example Sentences:

  • (1) The role of Ca2+ in cell agglutination may be either to activate the cell-surface dextran receptor or to form specific intercellular Ca2+ bridges.
  • (2) Data from cases with myocardial bridges show that both fatty streaks and raised lesions are seldom observed in the region distal to myocardial bridge.
  • (3) which suggest that ~60-90% of the cross-bridges attached in rigor are attached in relaxed fibers at an ionic strength of 20 mM and ~2-10% of this number of cross-bridges are attached in a relaxed fiber at an ionic strength of 170 mM.
  • (4) Terry Waite Chair, Benedict Birnberg Deputy chair, Antonio Ferrara CEO The Prisons Video Trust • If I want to build a bridge, I call in a firm of civil engineers who specialise in bridge-building.
  • (5) Brief digestion at neutral pH without reduction produced a molecule in which the Fab and Fc fragments were still linked by a pair of labile disulphide bridges, and the Fc fragment released by cleaving these bonds, called 1Fc fragment, contained a portion of the ;hinge' region including an interchain disulphide bridge.
  • (6) Acute coronary angiography showed myocardial bridging and total occlusion of the left anterior descending artery in the middle one-third of its course.
  • (7) These force-generators are identified with projections (cross-bridges) on the thick filament, each consisting of part of a myosin molecule.
  • (8) Segmental function was diminished an average of 67.8% in "noses" and 46.6% in "bridges".
  • (9) Gibbs was sent off in the first half at Stamford Bridge for handball, despite replays clearly showing it was his team-mate Alex Oxlade-Chamberlain who illegally deflected an Eden Hazard shot.
  • (10) Close van der Waals' contacts between the Cys22-Cys63 and Cys51-Cys75 disulfide bridges and the central hydrophobic core composed of the Trp25, Leu46, His48a and Trp62 side-chains are among the distinguishing features of the kringle 2 fold.
  • (11) The reactivity of the three disulphide bridges of insulin towards sodium sulphite was studied by amperometric titration of the liberated thiol groups.
  • (12) The cartilage of the concha is a valuable substitute of the bridge and the posterior wall of the external auditory conduct.
  • (13) It is shown from an analysis of the transient force responses observed after sudden changes in muscle length applied both at full and reduced overlap and during the rising phase of short tetani that these responses can be explained on the basis of varying numbers of cross bridges attached at the time of the length step.
  • (14) A two-lane, 400m bridge – funded by Jica, Japan's aid agency – coupled with simplified procedures agreed by Zambia and Zimbabwe have speeded up processing time.
  • (15) The dynamic properties of cross-bridge movement were investigated in glycerol-treated muscle fibers under various conditions by analyzing tension responses to two types of length change.
  • (16) The first problem facing Calderdale is sheep-rustling Happy Valley – filmed around Hebden Bridge, with its beautiful stone houses straight off the pages of the Guardian’s Lets Move To – may be filled with rolling hills and verdant pastures, but the reality of rural issues are harsh.
  • (17) It is suggested that a general manner of folding may be a common feature of the heterogeneous population of kappa-chains: one bridge which folds an invariable stretch of the chain, another bridge which folds a stretch that varies from protein to protein, and a bridge at the C-terminus which is the interchain link.
  • (18) 1-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-3-(2-chloroethyl)-3- nitrosourea hydrochloride (ACNU) causes chloroethylation of DNA strand followed by cross linking through an ethylene bridge.
  • (19) Optimal staining of antigen rich tissue, such as frozen sections, with the peroxidase antiperoxidase method required low antiserum concentrations apparently to minimize the binding of both antigen-binding fragments of the bridging antibody to the tissue bound antiserum.
  • (20) The results provided information on the energetics of actin-myosin-ligand states that occur in the portion of the cross-bridge cycle where MgATP binds to myosin.

Chain


Definition:

  • (n.) A series of links or rings, usually of metal, connected, or fitted into one another, used for various purposes, as of support, of restraint, of ornament, of the exertion and transmission of mechanical power, etc.
  • (n.) That which confines, fetters, or secures, as a chain; a bond; as, the chains of habit.
  • (n.) A series of things linked together; or a series of things connected and following each other in succession; as, a chain of mountains; a chain of events or ideas.
  • (n.) An instrument which consists of links and is used in measuring land.
  • (n.) Iron links bolted to the side of a vessel to bold the dead-eyes connected with the shrouds; also, the channels.
  • (n.) The warp threads of a web.
  • (v. t.) To fasten, bind, or connect with a chain; to fasten or bind securely, as with a chain; as, to chain a bulldog.
  • (v. t.) To keep in slavery; to enslave.
  • (v. t.) To unite closely and strongly.
  • (v. t.) To measure with the chain.
  • (v. t.) To protect by drawing a chain across, as a harbor.

Example Sentences:

  • (1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
  • (2) In addition, DDT blocked succinate dehydrogenase and the cytochrome b-c span of the electron transport chain, which also secondarily reduced ATP synthesis.
  • (3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
  • (4) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
  • (5) We have examined overlapping octapeptides from the kappa IIIb light chain variable region and show that some framework peptides have the ability to bind aggregated IgG.
  • (6) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
  • (7) The lineage and clonality of Hodgkin's disease (HD) were investigated by analyzing the organization of the immunoglobulin and T-cell receptor beta-chain (T beta) gene loci in 18 cases of HD, and for comparison, in a panel of 103 cases of B- and T-cell non-Hodgkin's lymphomas (NHLs) and lymphoid leukemias (LLs).
  • (8) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
  • (9) Approximately 90% of the patients have a lambda light chain myeloma protein and almost all patients excrete Bence-Jones protein.
  • (10) The reducing equivalents could be donated by formate or NADH through some segment of the membrane respiratory chain.
  • (11) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
  • (12) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
  • (13) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
  • (14) Peptide:N-glycosidase F removed both the asparagine-linked oligosaccharide chains of ricin B-chain in the absence of lactose.
  • (15) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
  • (16) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
  • (17) The canine system allows quantitative separation of native heme containing alpha and beta chains which recombine to for tetrameric hemoglobin with normal functional properties (n = 2.17).
  • (18) The product of this enzymatic hydrolysis was F420 with one less glutamic acid in the side chain.
  • (19) The present study deals with 832 ossicular chain reconstruction procedures performed in 655 patients from January 1975 to December 1985.
  • (20) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.