(a.) Having dark streaks or spots on a gray or tawny ground; brinded.
Example Sentences:
(1) The brindled mottled mutant mouse, a model of Menkes' disease, has alterations in copper homeostasis which cause, among other sequelae, neuronal degeneration in selected areas of brain.
(2) David Brindle is the Guardian’s public services editor Read more • New series: careers in public services • Why there won’t be mass redundancies in the public sector after the election This article is part of our series on careers in public services .
(3) Neuropathological and enzyme-histochemical studies were performed on brindled mouse hemizygotes (BMs) and normal littermates at the age of 2 days, 7 days, 11 days and 14 days, together with an investigation of their tissue copper levels.
(4) During early development normal and brindled mouse brain use 3-hydroxy-butyrate preferentially to glucose as a source for biosynthetic carbon units.
(5) The most extensively investigated mutants are the mottled mice, in particular brindled mice, which have a mutation analogous to that of Menkes' disease.
(6) Irrespective of how the low levels of the approximately 48-kDa protein may be related to the basic defect in the brindled mice, the data are consistent with an important role for the approximately 48-kDa protein in intracellular copper metabolism.
(7) Brindled mice, which have a genetic defect that affects copper distribution, were compared to their normal brothers.
(8) These results suggest that fetal brain abnormalities caused by Trien-2HCl may be due in part to induction of copper deficiency, which is almost equivalent to that in brindled mutant mouse.
(9) Decreased copper binding and approximately 48-kDa protein were not simply secondary to the abnormal hepatic and renal copper levels that are found in the brindled mice since although their liver copper levels are low, their kidney copper levels are high.
(10) Copper (6 ppm) was administered to pregnant heterozygous brindled and normal mice from 13 to 18 days gestation.
(11) Brindled mice from dams on the -Cu treatment were smaller and had lower packed cell volumes than brindled mice from dams on the +Cu treatment.
(12) Most of the copper in the cytosol of these fibroblasts is bound to metallothionein (MT), which is elevated in Menkes or brindled mouse fibroblasts.
(13) Proteolytically generated fragments of the microfilament anchoring protein brain spectrin were found to accumulate in brindled mouse brain.
(14) At the table David Brindle (Chair) Public services editor, the Guardian Sharon Allen Chief executive, Skills for Care Pete Calveley Chief executive, Barchester Healthcare Michelle Dudderidge Director, Hand in Hands Shaks Ghosh Chief executive, Clore Social Leadership Programme Patrick Vernon Project coordinator, Health Partnership Project, National Housing Federation Martin Green Chief executive, Care England Ray James President, Association of Directors of Adult Social Services in England Des Kelly Executive director, National Care Forum John Kennedy Director of care services, Joseph Rowntree Foundation Neil Matthewman Chief executive, Community Integrated Care John Ransford Non-executive director, HC-One Jon Glasby Professor of health and social care, University of Birmingham Bridget Warr Chief executive, UK Home Care Association There was a recognition from participants that there were some great leaders in social care – but that there was room for improvement, too.
(15) These data show that female brindled mice have neurochemical abnormalities similar to (if less severe than) the male hemizygotes, that these abnormalities are regionally specific, are most apparent prior to 30 days of age, and are linked to behavioral deficits.
(16) Histochemical examinations showed no significant differences in the stainability, morphology and distribution of MAO positive neurons in the brain between normal and brindled mice at the same age.
(17) Copper accumulation by normal fibroblasts containing excess MT was examined to determine if the excess copper accumulation phenotype was secondary to excess MT or associated with the primary defect in fibroblasts from the brindled mice.
(18) Nucleotide levels were low in spleens from brindled mice.
(19) Deficits in oxidative and acetylcholine metabolism occur in the developing brindled mouse, a genetic mutant with a defect in copper homeostasis.
(20) In order to investigate the levels of cytochrome oxidase activity in neuronal mitochondria in the brain of the brindled mouse hemizygote (BM), the cerebella and brain stems from 12 pairs of brindled and normal littermates aged 13-16 days were examined.
Streaky
Definition:
(a.) Same as Streaked, 1.
Example Sentences:
(1) Some of our favourite things to stir in include: chickpeas and fried chorizo pieces; crisply fried smoked streaky bacon and frozen peas; chunks of aubergine fried in a pan, crumbled ricotta or cream cheese on top; capers and basil; chopped anchovies, a little cream and chopped rosemary; wilted rocket with crumbled feta on top; or chopped basil, a knob of butter, and a little balsamic.
(2) Excretory urography of a patient with an early stage of medullary cystic disease demonstrated an inhomogeneous, streaky nephrogram confined to the medulla, presumably due to accumulation of contrast material in dilated tubules.
(3) Let’s wind him up by cleaning the condensation off the inside of the windows using our bare hands.” That grey-haired guy in Sherlock would get really angry if you cleaned the condensation off the inside of his car windows with your bare hands; he’d shout-talk something about streaky finger marks.
(4) Full English breakfast SERVES 4 sausages 4 vegetable oil smoked streaky bacon 200g plum tomatoes 2 salt Portobello mushrooms 4 butter chicken stock 200ml thyme 1 sprig garlic 2 cloves, crushed black pudding 4 thick (1.5cm) slices free-range eggs 4 bread toasted Start with the sausages For me, it's about finding great ingredients and treating them with respect, as if you were building a wall or making a beautiful piece of furniture.
(5) In addition to a nodular pattern, reticulo-nodular, reticular, diffuse infiltrative and streaky shadowing due to fibrosis could be recognised.
(6) Low molecular weight proteins were resolvable into a few diffuse and streaky bands by dodecyl sulfate and chloral hydrate polyacrylamide gel electrophoresis, the former giving superior reso-ution.
(7) Twenty-one of these (3 symptomatic, 18 asymptomatic) developed subpleural pulmonary abnormalities which were streaky or reticular in 7, homogeneous with a broad base against pleura in 3 and had a mixed pattern in 11 patients.
(8) Popovich pulls Green, AGAIN, one good way to break up a streaky player's confidence that.
(9) Skylarks are smallish, brown birds with a perky crest and streaky plumage.
(10) Yet Danny Rose’s streaky goal sparked the Spurs fightback and although this was not the result that they wanted in the race for a top-four finish – and to capitalise on Manchester United’s loss at Swansea City on Saturday – they were more than happy to take it.
(11) The only sketch comedian who really preceded them was Spike Milligan, and his work was streaky, too.
(12) If you slap on too many coats it goes all streaky, too few and it just looks weak.
(13) The CT findings were linear and streaky densities in the pericecal fat compatible with pericecal inflammation (seven cases), intramural abscess (one case), thickening of the cecal wall (two cases), and cecal diverticulum (one case).
(14) As a result, the press had approximately 200m images of crying Brazilian faces to choose from: players, politicians, fans with streaky face paint, families in favelas, children wearing glasses, old men with moustaches clutching replica trophies, jaguars in the rainforest.
(15) The distinctive radiographic feature in the child was an endosteal pattern of hyperostosis marked by streakiness of the long bones and spotting of the small.
(16) The radiographic pattern in the course of experimentally infected Rhesus monkeys with the two African fluke species Paragonimus africanus and P. uterobilateralis consist of hilar dilatation, streaky, patchy or diffuse shadows, cavities, atelectases and pleural reactions.
(17) We needed a different way to try to penetrate, and David found more room in the second half.” Manchester City’s Raheem Sterling: I did not say I was too tired to play for England Read more While there was a touch of good fortune about Agüero’s second, a deflection off Yoan Gouffran making life difficult for Krul when the goalkeeper might otherwise have had the shot covered, there was nothing streaky about the rest.
(18) Serves 4 1.2kg potatoes, preferably Maris Piper or King Edward, peeled and cut into roughly 4cm chunks 1 small green savoy cabbage (about 450g), trimmed and finely shredded 75g butter, cubed 6 rindless smoked streaky bacon rashers, cut into 3cm pieces 6 spring onions, trimmed and finely sliced 125ml double cream 4 large fridge-cold eggs Flaked sea salt Freshly ground black pepper 1 Put the potatoes in a large saucepan and cover with cold water.
(19) When your city’s default backdrop is drizzle, streaky concrete and endless branches of Greggs, it’s easy to yearn wistfully for sparkling skyscrapers, chrome-plated diners and avenue canyons stretching to infinity.
(20) In addition to predominating basally localized streaky-nodular lung changes all patients had hepatosplenomegaly and granulomatous infections of other organs.