(superl.) Wide; extend in breadth, or from side to side; -- opposed to narrow; as, a broad street, a broad table; an inch broad.
(superl.) Extending far and wide; extensive; vast; as, the broad expanse of ocean.
(superl.) Extended, in the sense of diffused; open; clear; full.
(superl.) Fig.: Having a large measure of any thing or quality; not limited; not restrained; -- applied to any subject, and retaining the literal idea more or less clearly, the precise meaning depending largely on the substantive.
(superl.) Comprehensive; liberal; enlarged.
(superl.) Plain; evident; as, a broad hint.
(superl.) Free; unrestrained; unconfined.
(superl.) Characterized by breadth. See Breadth.
(superl.) Cross; coarse; indelicate; as, a broad compliment; a broad joke; broad humor.
(superl.) Strongly marked; as, a broad Scotch accent.
(n.) The broad part of anything; as, the broad of an oar.
(n.) The spread of a river into a sheet of water; a flooded fen.
(n.) A lathe tool for turning down the insides and bottoms of cylinders.
Example Sentences:
(1) As a group, the three mammalian proteins resemble bovine serum conglutinin and behave as lectins with rather broad sugar specificities directed at certain non-reducing terminal N-acetylglucosamine, mannose, glucose and fucose residues, but with subtle differences in fine specificities.
(2) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
(3) Faisal Abu Shahla, a senior official in Fatah, an organisation responsible for a good deal of repression of its own when it was in power, accuses Hamas of holding 700 political prisoners in Gaza as part of a broad campaign to suppress dissent.
(4) Accordingly, when bFGF, complexed to heparin, is treated with pepsin A, an aspartic protease with a broad specificity, only the Leu9-Pro10 peptide bond is cleaved generating the 146-amino acid form.
(5) A broad specificity of LipDH was observed for the glycine cleavage system.
(6) Time-resolved tyrosine fluorescence anisotropy shows global correlation times broadly in agreement with the NMR results, but with an additional faster correlation time [approximately 600 ps].
(7) Cefuzoname seems to be among the middle ranks of beta-lactam agents as far as penetration rate is concerned; however, when its potent antibacterial activity and broad spectrum are taken into account, the concentrations in CSF in patients with meningitis seem worth examining.
(8) It was possible to classify the bacteriophages broadly, according to the variety of mutants that were resistant to them.
(9) The surface film transition is especially noted in the pressure-area curve of the surfactant and approximates in two dimensions the broad thermotropic phase transition of the bulk phase surfactant.
(10) If Clegg's concerns do broadly accord with Cameron's, how will the PM sell such a big U-turn to his increasingly anti-Clegg backbenchers?
(11) Federal endorsement of the HMO concept has resulted in broad understanding of a number of concepts unknown in fee-for-service medicine.
(12) Broad-based secular comprehensives that draw in families across the class, faith and ethnic spectrum, entirely free of private control, could hold a new appeal.
(13) A library of Zymomonas mobilis genomic DNA was constructed in the broad-host-range cosmid pLAFR1.
(14) Amphotericin B has a broad spectrum of action that includes most of the major fungal pathogens of man.
(15) All other broad-spectrum benzimidazole anthelmintics, regardless of substituent at the 2 position (methyl carbamate or thiazolyl group), are flat.
(16) As Kuwait is one of the countries where the total consumption of antibiotics is very high as compared to most of the western countries, we are inclined to assume that this generous policy for the prescription of especially ampicillin and other broad spectrum antibiotics in uncomplicated infections has generated this serious consequence.
(17) Learning to do this well involves acquiring a broad base of knowledge and a complex range of skills.
(18) The narrow latency window contained significantly more responses than could be explained by the spontaneous activity rate, but this was not true for the added time permitted by the broad window.
(19) Taxol has been demonstrated in numerous laboratories worldwide to have broad-spectrum antitumor activity against many tumor models.
(20) This strain of the organism fits a pattern of susceptibility that is rare among N asteroides isolates in general and has been called the type 5 pattern, described as a resistance to broad spectrum cephalosporins, ciprofloxacin, and all aminoglycosides except amikacin.
Scrape
Definition:
(v. t.) To rub over the surface of (something) with a sharp or rough instrument; to rub over with something that roughens by removing portions of the surface; to grate harshly over; to abrade; to make even, or bring to a required condition or form, by moving the sharp edge of an instrument breadthwise over the surface with pressure, cutting away excesses and superfluous parts; to make smooth or clean; as, to scrape a bone with a knife; to scrape a metal plate to an even surface.
(v. t.) To remove by rubbing or scraping (in the sense above).
(v. t.) To collect by, or as by, a process of scraping; to gather in small portions by laborious effort; hence, to acquire avariciously and save penuriously; -- often followed by together or up; as, to scrape money together.
(v. t.) To express disapprobation of, as a play, or to silence, as a speaker, by drawing the feet back and forth upon the floor; -- usually with down.
(v. i.) To rub over the surface of anything with something which roughens or removes it, or which smooths or cleans it; to rub harshly and noisily along.
(v. i.) To occupy one's self with getting laboriously; as, he scraped and saved until he became rich.
(v. i.) To play awkwardly and inharmoniously on a violin or like instrument.
(v. i.) To draw back the right foot along the ground or floor when making a bow.
(n.) The act of scraping; also, the effect of scraping, as a scratch, or a harsh sound; as, a noisy scrape on the floor; a scrape of a pen.
(n.) A drawing back of the right foot when bowing; also, a bow made with that accompaniment.
(n.) A disagreeable and embarrassing predicament out of which one can not get without undergoing, as it were, a painful rubbing or scraping; a perplexity; a difficulty.
Example Sentences:
(1) In invasive epidermoid carcinoma, the accuracy with the self-collected specimens approached the physician-scraped specimens.
(2) A microsomal preparation containing labeled endocytic vesicles was prepared by cell scraping, homogenization, and differential centrifugation.
(3) We compared two noninvasive methods of sampling exfoliated cervical cells--cervicovaginal lavage and scrape-Cytobrush.
(4) We therefore surveyed patients with Parkinson's disease (PD) regarding early adult consumption of fruits and vegetables usually eaten raw, with seeds that are swallowed or scraped with the teeth.
(5) The heads were examined for adult and larval meningeal worms (Parelaphostrongylus tenuis) by physical examination of the brain surfaces, and the Baermann technique, respectively, and for ear mites by examination of ear scrapings.
(6) He was competing in his third Boston marathon, and he came away with a scraped knee and a feeling of shock.
(7) Through small and large acts of deprivation and destruction we follow the process: the removal of hope, of dignity, of luxury, of necessity, of self; the reduction of a man to a hoarder of grey slabs of bread and the scrapings of a soup bowl (wonderfully told all this, with a novelist's gift for detail and sometimes very nearly comic surprise), to the confinement of a narrow bed – in which there is "not even any room to be afraid" – with a stranger who doesn't speak your language, to the cruel illogicality of hating a fellow victim of oppression more than you hate the oppressor himself – one torment following another, and even the bleak comfort of thinking you might have touched rock bottom denied you as, when the most immediate cause of a particular stress comes to an end, "you are grievously amazed to see that another one lies behind; and in reality a whole series of others".
(8) Psoriatic skin scales, non-sterile and sterile, were tested for stimulatory effect on PMNs and compared with the effect of normal skin scrapings.
(9) Our data provide the first evidence in humans that significant inflammatory changes in conjunctival scrapings are present long after allergen exposure has ended.
(10) This was partly because of its composition, scraped together from around the world but without the backing of Arab and Muslim leaders.
(11) Read more on Scottish independence • ' I believe in solidarity with the folk living south of Carlisle ' • ' The UK is on shifting sands – we can't assume survival ' • ' Better Together is truly scraping the barrel now ' The fact is that far from fearing the breakup of the UK, the English are looking at the benefits that devolution has brought the Scots and asking why they are not able to enjoy the same.
(12) Cellular abnormalities were demonstrated in 90.4% of women having scrapings of visible lesions and in 88.1% of women studied by 4-quadrant vaginal scrapings in the absence of clinical disease.
(13) These problems were met by introducing the indicator into the cells with the scrape-loading technique adapted for use with Dictyostelium and the construction of a new fura-2 derivative, fura-2-dextran.
(14) The overlying superficial and wing cells were removed by mechanical scraping to expose basal cells attached to their basal lamina.
(15) Scrapes detected more HPV 18 (10% vs. 2%, P = less than 0.05) and HPV 31 (7% vs. 3%, not significant) than did the biopsies, but biopsies detected more HPV 16 (42% vs. 33%, not significant).
(16) Epithelial cells were scraped from the tonsillar surfaces of 15 patients with current acute tonsillitis (AT) and of 15 individually matched healthy persons.
(17) We compared swab and scraping (Rhino-probe) technics in the nasal cytology obtention for eosinophils count in 36 patients with a range of 2-46 years old (mean age 18.6 years) with diagnosis of Allergic Rhinitis.
(18) Morphologically distinguishable differences in enamel at the occlusal site was examined as to whether the tooth is treated by acid solution, low-viscosity acid gel, or high-viscosity acid gel as well as the extent of involvement, using either a conventional or scraping method of application.
(19) Fifteen New Zealand white rabbits underwent laparotomy, with scrape and cut lesions created bilaterally on the uterine body and horns, respectively.
(20) The conjunctival sheets were cultured on epithelial-scraped corneal stromal carriers in vitro.