(superl.) Wide; extend in breadth, or from side to side; -- opposed to narrow; as, a broad street, a broad table; an inch broad.
(superl.) Extending far and wide; extensive; vast; as, the broad expanse of ocean.
(superl.) Extended, in the sense of diffused; open; clear; full.
(superl.) Fig.: Having a large measure of any thing or quality; not limited; not restrained; -- applied to any subject, and retaining the literal idea more or less clearly, the precise meaning depending largely on the substantive.
(superl.) Comprehensive; liberal; enlarged.
(superl.) Plain; evident; as, a broad hint.
(superl.) Free; unrestrained; unconfined.
(superl.) Characterized by breadth. See Breadth.
(superl.) Cross; coarse; indelicate; as, a broad compliment; a broad joke; broad humor.
(superl.) Strongly marked; as, a broad Scotch accent.
(n.) The broad part of anything; as, the broad of an oar.
(n.) The spread of a river into a sheet of water; a flooded fen.
(n.) A lathe tool for turning down the insides and bottoms of cylinders.
Example Sentences:
(1) As a group, the three mammalian proteins resemble bovine serum conglutinin and behave as lectins with rather broad sugar specificities directed at certain non-reducing terminal N-acetylglucosamine, mannose, glucose and fucose residues, but with subtle differences in fine specificities.
(2) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
(3) Faisal Abu Shahla, a senior official in Fatah, an organisation responsible for a good deal of repression of its own when it was in power, accuses Hamas of holding 700 political prisoners in Gaza as part of a broad campaign to suppress dissent.
(4) Accordingly, when bFGF, complexed to heparin, is treated with pepsin A, an aspartic protease with a broad specificity, only the Leu9-Pro10 peptide bond is cleaved generating the 146-amino acid form.
(5) A broad specificity of LipDH was observed for the glycine cleavage system.
(6) Time-resolved tyrosine fluorescence anisotropy shows global correlation times broadly in agreement with the NMR results, but with an additional faster correlation time [approximately 600 ps].
(7) Cefuzoname seems to be among the middle ranks of beta-lactam agents as far as penetration rate is concerned; however, when its potent antibacterial activity and broad spectrum are taken into account, the concentrations in CSF in patients with meningitis seem worth examining.
(8) It was possible to classify the bacteriophages broadly, according to the variety of mutants that were resistant to them.
(9) The surface film transition is especially noted in the pressure-area curve of the surfactant and approximates in two dimensions the broad thermotropic phase transition of the bulk phase surfactant.
(10) If Clegg's concerns do broadly accord with Cameron's, how will the PM sell such a big U-turn to his increasingly anti-Clegg backbenchers?
(11) Federal endorsement of the HMO concept has resulted in broad understanding of a number of concepts unknown in fee-for-service medicine.
(12) Broad-based secular comprehensives that draw in families across the class, faith and ethnic spectrum, entirely free of private control, could hold a new appeal.
(13) A library of Zymomonas mobilis genomic DNA was constructed in the broad-host-range cosmid pLAFR1.
(14) Amphotericin B has a broad spectrum of action that includes most of the major fungal pathogens of man.
(15) All other broad-spectrum benzimidazole anthelmintics, regardless of substituent at the 2 position (methyl carbamate or thiazolyl group), are flat.
(16) As Kuwait is one of the countries where the total consumption of antibiotics is very high as compared to most of the western countries, we are inclined to assume that this generous policy for the prescription of especially ampicillin and other broad spectrum antibiotics in uncomplicated infections has generated this serious consequence.
(17) Learning to do this well involves acquiring a broad base of knowledge and a complex range of skills.
(18) The narrow latency window contained significantly more responses than could be explained by the spontaneous activity rate, but this was not true for the added time permitted by the broad window.
(19) Taxol has been demonstrated in numerous laboratories worldwide to have broad-spectrum antitumor activity against many tumor models.
(20) This strain of the organism fits a pattern of susceptibility that is rare among N asteroides isolates in general and has been called the type 5 pattern, described as a resistance to broad spectrum cephalosporins, ciprofloxacin, and all aminoglycosides except amikacin.
Thick
Definition:
(superl.) Measuring in the third dimension other than length and breadth, or in general dimension other than length; -- said of a solid body; as, a timber seven inches thick.
(superl.) Having more depth or extent from one surface to its opposite than usual; not thin or slender; as, a thick plank; thick cloth; thick paper; thick neck.
(superl.) Dense; not thin; inspissated; as, thick vapors. Also used figuratively; as, thick darkness.
(superl.) Not transparent or clear; hence, turbid, muddy, or misty; as, the water of a river is apt to be thick after a rain.
(superl.) Abundant, close, or crowded in space; closely set; following in quick succession; frequently recurring.
(superl.) Not having due distinction of syllables, or good articulation; indistinct; as, a thick utterance.
(superl.) Deep; profound; as, thick sleep.
(superl.) Dull; not quick; as, thick of fearing.
(superl.) Intimate; very friendly; familiar.
(n.) The thickest part, or the time when anything is thickest.
(n.) A thicket; as, gloomy thicks.
(adv.) Frequently; fast; quick.
(adv.) Closely; as, a plat of ground thick sown.
(adv.) To a great depth, or to a greater depth than usual; as, land covered thick with manure.
(v. t. & i.) To thicken.
Example Sentences:
(1) The variation in thickness of the LLFL may modulate the species causing damage to the cells below it.
(2) An increase in membrane thickness was observed on phosphorylation.
(3) All patients with localized subaortic hypertrophy had left ventricular hypertrophy (left ventricular mass or posterior wall thickness greater than 2 SD from normal) with a normal size cavity due to aortic valve disease (2 patients were also hypertensive).
(4) Milk yield and litter weights were similar but backfat thickness (BF) was greater in 22 C sows (P less than .05) compared to 30 C sows.
(5) The enzyme was quantitated by incubation of 16-micron-thick brain sections with 0.07-2 nM of the converting enzyme inhibitor 125I-351A and comparison to 125I-standards.
(6) Grafts of intermediate thickness (M III) showed excellent clinical healing of the donor and the recipient site.
(7) At 7 days axonal swellings were infrequently observed and the main structural feature was a reduction in myelin thickness in affected nerve fibers.
(8) Suspensions of isolated insect flight muscle thick filaments were embedded in layers of vitreous ice and visualized in the electron microscope under liquid nitrogen conditions.
(9) The NAD-dependent enzymes (except alpha-GPDH) showed a stronger reactivity in the proximal tubules, while the NADP-dependent ones were more reactive in the thick limb of Henle's loop and distal convoluted tubules.
(10) In clinical situations on donor sites and grafted full-thickness burn wounds, the PEU film indeed prevented fluid accumulation and induced the formation of a "red" coagulum underneath.
(11) These early hyperplastic lesions revealed stellate-shaped dilated bile canaliculi lined by blebs and abnormally thick elongated microvilli, a decreased number of microvilli on the sinusoidal surface, a marked increase in smooth endoplasmic reticulum, large nucleoli, and bundles of pericanalicular microfilaments.
(12) The degree of overlap varies with the thickness of the arborization and is in the order of 1-2 mu.
(13) The spatial resolution of a NaI(T1), 25 mm thick bar detector designed for use in positron emission tomography has been studied.
(14) In the longitudinal direction, however, spatial resolution of under slice thickness could not be obtained.
(15) Thus, multiparae had very thick border zones composed predominantly of large nodules and, additionally, of vacuolated cells and fibrous tissue.
(16) The thickness of the media in the groups behaves like the number of nuclei: in hypertension with the highest values, there is no significant decrease as far as the 8th cross-section, while in the coronary sclerosis and third decade groups the values come closer together after the 6th cross-section.
(17) A model for left ventricular diastolic mechanics is formulated that takes into account noneligible wall thickness, incompressibility, finite deformation, nonlinear elastic effects, and the known fiber architecture of the ventricular wall.
(18) These force-generators are identified with projections (cross-bridges) on the thick filament, each consisting of part of a myosin molecule.
(19) Piretanide blocks the Na+ 2Cl- K+ cotransporter protein in the thick ascending limb (TAL) of the loop of Henle reversibly.
(20) Dioptric aniseikonia was calculated between 1 month and 24 months after surgery (with Gruber's and Huber's computer program) on the basis of most recently obtained values (bulb axis length, depth of the anterior chamber, lens thickness, necessary refraction), and compared with subjective measurements taken with the phase difference haploscope.