(n.) One of the elements, related in its chemical qualities to chlorine and iodine. Atomic weight 79.8. Symbol Br. It is a deep reddish brown liquid of a very disagreeable odor, emitting a brownish vapor at the ordinary temperature. In combination it is found in minute quantities in sea water, and in many saline springs. It occurs also in the mineral bromyrite.
Example Sentences:
(1) Samples of raw cereals imported in Italy and of other foodstuffs that can be treated with bromine-containing fumigants were analysed for the total bromide content.
(2) The normal levels of bromine in human tissue are given and their use in the interpretation of levels found when over-exposure is a possibility is described.
(3) Z-DNA antigen was prepared against poly(dG-dC).poly(dG-dC), which had been converted to the Z-helix conformation in high salt and then stabilized by bromination.
(4) It is found that each of these polymers, including those with brominated bases and those with the four different bases, have a characteristic negative feature at short wavelengths when in the Z form.
(5) Synthesis of hexabromonaphthalenes (HBNs) by direct bromination of naphthalene results in a mixture of two isomers.
(6) In this report the accuracy of this method is established by comparison of spin-label quenching to that obtained using brominated lipids.
(7) 8-Bromo-2'-omicron-acetylinosine cyclic 3',5'-phosphate and 8-[(p-chlorophenyl)thio]-2'-omicron-acetylinosine cyclic 3',5'-phosphate were produced by acylation of 8-bromoinosine cyclic 3',5'-phosphate and 8-[(p-chlorophenyl)thio]inosine cyclic 3',5'-phosphate, respectively; while 8-bromo-2'-omicron-butyrylguanosine cyclic 3',5'-phosphate was synthesized by bromination of 2'-omicron-butyrylguanosine cyclic 3',5'-phosphate.
(8) [14C]Bromomisonidazole was prepared by direct bromination of [ring-2] [14C]misonidazole in dioxane.
(9) In November 1984, because of an accident at a chemical plant, the population of a large area in the town of Geneva, Switzerland, was exposed to toxic bromine gas during several hours at concentrations above the short-term exposure limit.
(10) The absolute configuration of the compound was determined by X-ray structure analysis of its dihydrobromide using the anomalous dispersion of bromine.
(11) The hepatic levels of triglycerides, total proteins and glycogen, as well as the weight gain and caloric intake of the animals which were fed 0.1 g of brominated oil per 100 g diet, were similar to those of the control group.
(12) Substrate specificity towards chlorinated and brominated substrates was limited to short chain monosubstituted 2-halocarboxylic acids.
(13) The minor isomer is definitively identified as 2,3,4,5,6,7-HBN by high-field nuclear magnetic resonance (NMR) spectroscopic analysis of brominated [1-13C]naphthalene-derived products.
(14) None of the patients developed brominism or bromine intoxication.
(15) Electrophilic substitution (chlorination, bromination, and iodination) was effected at the C-5 position of compound 3 with N-chlorosuccinimide, N-bromosuccinimide, and iodine monochloride, respectively, in methylene chloride.
(16) Various soluble tracers were evaluated, among them indium, scandium, and bromine.
(17) This allows a bromine (microgram) to chlorine (mg) ratio to be established (3.2) above which bromine exposure must be considered.
(18) Both dehalogenases show a broad substrate specificity, allowing the degradation of bromine- and chlorine-substituted organic compounds.
(19) The relationship among iodine, bromine and chlorine concentrations in cow's milk samples in Japan was studied with a regression analysis.
(20) The first enzyme was a halophenol para-hydroxylase, a membrane-associated monooxygenase that required molecular oxygen and catalyzed the para-hydroxylation and dehalogenation of chlorinated, fluorinated, and brominated phenols to the corresponding halogenated hydroquinones.
Bromoform
Definition:
(n.) A colorless liquid, CHBr3, having an agreeable odor and sweetish taste. It is produced by the simultaneous action of bromine and caustic potash upon wood spirit, alcohol, or acetone, as also by certain other reactions. In composition it is the same as chloroform, with the substitution of bromine for chlorine. It is somewhat similar to chloroform in its effects.
Example Sentences:
(1) GSH alone did not serve as a cofactor; however, GSH in the presence of NADPH and oxygen produced an 8-fold increase in the metabolism of bromoform to CO.
(2) Drinking water from several cities was analyzed for these trihalomethanes as well as for bromoform.
(3) Lower blood CO levels were found in rats given 2H-bromoform as compared to rats given bromoform.
(4) Of the 16 contaminants tested, only bromoform produced a pulmonary adenoma response that was significantly greater than the pulmonary adenoma response of vehicle-treated control mice.
(5) The administration of 13C-bromoform led to the formation of similarly enriched 13CO.
(6) The part gives some data about various light volatile halogenated hydrocarbons in surface waters of the industrialized city and its surroundings--the halogenated forms, chloroform and bromoform and the most used solvents trichloroethylene, tetrachloroethylene, tetrachloromethane and 1,1,2,2-tetrachloroethane.
(7) Seventeen of the 53 compounds (acetaldehyde, 2-aminoanthracene, bromoform, t-butyl hydroperoxide, chlorambucil, trans-cinnamaldehyde, crotonaldehyde, 1,3-dichloro-5,5-dimethylhydantoin, 3,4-dichloronitrobenzene, dimethoxane, 2,4-dinitrotoluene, 1,2-epoxy-3,3,3-trichloropropane, formaldehyde, furfural, halothane, HC yellow 4, and picric acid) were found to induce lethal mutations and three (2-aminoanthracene, chlorambucil,and crotonaldehyde) also induced reciprocal translocations.
(8) 80% of the concentrations of chloroform, tri- and tetrachloroethylene were in the range of less than 1 microgram l-1, 90% of bromoform, tetrachloromethane and 1,1,2,2-tetrachloroethane were found to amount less than 0.1 microgram l-1.
(9) Furthermore, SKF 525-A significantly inhibited the in vivo metabolism of bromoform to CO. Administration of either diethyl maleate or D-penicillamine did not alter the blood CO levels produced in response to bromoform administration.
(10) The amount of TBARS released from liver slices incubated with bromotrichloromethane, carbon tetrabromide, dichloromethane, bromobenzene, chloroform, bromoform, benzyl chloride, bromochloromethane, and carbon tetrabromide correlated with the lethality of these compounds as evaluated by their oral LD50 in rats.
(11) The finely powdered material was fractionated in a density gradient of acetone and bromoform in varying proportions.
(12) Test chemicals included trichloroethylene, vinylidene chloride, bis(2-chloroethyl)ether, ethylene dichloride, and a mixture of carbon tetrachloride, trichloroethylene, chloroform, bromodichloromethane, chlorodibromomethane and bromoform.
(13) The bone powder was then fractionated in a bromoform-toluene density gradient to determine its mineralization profile (Ca, P, CO3, and osteocalcin), and X-ray diffraction was used to determine apatite crystal size in some fractions.
(14) It was found that phenobarbital, but not 3-methylcholanthrene, treatment increased the blood CO levels seen after the administration of bromoform as compared to saline-treated controls.
(15) It is generated readily by bombarding nearly saturated aqueous solutions of bromide salts, or bromoform, with 14-MeV protons.
(16) Cytochrome P-450 was found to bind bromoform to produce a type I binding spectrum.
(17) Mutagenicity with one or several procedures shows 1,1,2,2-tetrachloroethane, hexachloroethane, trichloroethylene, bromdichloromethane and bromoform without metabolic activation and dichloromethane, tetrachloromethane, 1,1,2,2-tetrachloroethane, hexachloroethane, 1,1-dichloroethylene, trans-1,2-dichloroethylene, tetrachloroethylene and bromdichloromethane with metabolic activation.
(18) The formation of PBN-free radical adducts has also been observed in phenobarbital-induced rats in vivo when intoxicated with chloroform, bromoform or iodoform, suggesting that the reductive metabolism of trihalomethanes might be of relevance to their established toxicity in the whole animal.
(19) Treatment of rats with phenobarbital or 3-methylcholanthrene increased the rate of conversion of bromoform to CO. Cobaltous chloride treatment of rats or storage of microsomal preparations at 4 degrees C reduced the rate of formation of CO from bromoform.
(20) The ability of carbon tetrabromide, benzyl chloride, bromoform, bromobenzene, carbon tetrachloride, chloroform, dichloromethane, and bromochloromethane to inhibit protein synthesis was correlated with their ability to induce lipid peroxidation, and with their LD50.