What's the difference between bromoform and tribromomethane?
Bromoform
Definition:
(n.) A colorless liquid, CHBr3, having an agreeable odor and sweetish taste. It is produced by the simultaneous action of bromine and caustic potash upon wood spirit, alcohol, or acetone, as also by certain other reactions. In composition it is the same as chloroform, with the substitution of bromine for chlorine. It is somewhat similar to chloroform in its effects.
Example Sentences:
(1) GSH alone did not serve as a cofactor; however, GSH in the presence of NADPH and oxygen produced an 8-fold increase in the metabolism of bromoform to CO.
(2) Drinking water from several cities was analyzed for these trihalomethanes as well as for bromoform.
(3) Lower blood CO levels were found in rats given 2H-bromoform as compared to rats given bromoform.
(4) Of the 16 contaminants tested, only bromoform produced a pulmonary adenoma response that was significantly greater than the pulmonary adenoma response of vehicle-treated control mice.
(5) The administration of 13C-bromoform led to the formation of similarly enriched 13CO.
(6) The part gives some data about various light volatile halogenated hydrocarbons in surface waters of the industrialized city and its surroundings--the halogenated forms, chloroform and bromoform and the most used solvents trichloroethylene, tetrachloroethylene, tetrachloromethane and 1,1,2,2-tetrachloroethane.
(7) Seventeen of the 53 compounds (acetaldehyde, 2-aminoanthracene, bromoform, t-butyl hydroperoxide, chlorambucil, trans-cinnamaldehyde, crotonaldehyde, 1,3-dichloro-5,5-dimethylhydantoin, 3,4-dichloronitrobenzene, dimethoxane, 2,4-dinitrotoluene, 1,2-epoxy-3,3,3-trichloropropane, formaldehyde, furfural, halothane, HC yellow 4, and picric acid) were found to induce lethal mutations and three (2-aminoanthracene, chlorambucil,and crotonaldehyde) also induced reciprocal translocations.
(8) 80% of the concentrations of chloroform, tri- and tetrachloroethylene were in the range of less than 1 microgram l-1, 90% of bromoform, tetrachloromethane and 1,1,2,2-tetrachloroethane were found to amount less than 0.1 microgram l-1.
(9) Furthermore, SKF 525-A significantly inhibited the in vivo metabolism of bromoform to CO. Administration of either diethyl maleate or D-penicillamine did not alter the blood CO levels produced in response to bromoform administration.
(10) The amount of TBARS released from liver slices incubated with bromotrichloromethane, carbon tetrabromide, dichloromethane, bromobenzene, chloroform, bromoform, benzyl chloride, bromochloromethane, and carbon tetrabromide correlated with the lethality of these compounds as evaluated by their oral LD50 in rats.
(11) The finely powdered material was fractionated in a density gradient of acetone and bromoform in varying proportions.
(12) Test chemicals included trichloroethylene, vinylidene chloride, bis(2-chloroethyl)ether, ethylene dichloride, and a mixture of carbon tetrachloride, trichloroethylene, chloroform, bromodichloromethane, chlorodibromomethane and bromoform.
(13) The bone powder was then fractionated in a bromoform-toluene density gradient to determine its mineralization profile (Ca, P, CO3, and osteocalcin), and X-ray diffraction was used to determine apatite crystal size in some fractions.
(14) It was found that phenobarbital, but not 3-methylcholanthrene, treatment increased the blood CO levels seen after the administration of bromoform as compared to saline-treated controls.
(15) It is generated readily by bombarding nearly saturated aqueous solutions of bromide salts, or bromoform, with 14-MeV protons.
(16) Cytochrome P-450 was found to bind bromoform to produce a type I binding spectrum.
(17) Mutagenicity with one or several procedures shows 1,1,2,2-tetrachloroethane, hexachloroethane, trichloroethylene, bromdichloromethane and bromoform without metabolic activation and dichloromethane, tetrachloromethane, 1,1,2,2-tetrachloroethane, hexachloroethane, 1,1-dichloroethylene, trans-1,2-dichloroethylene, tetrachloroethylene and bromdichloromethane with metabolic activation.
(18) The formation of PBN-free radical adducts has also been observed in phenobarbital-induced rats in vivo when intoxicated with chloroform, bromoform or iodoform, suggesting that the reductive metabolism of trihalomethanes might be of relevance to their established toxicity in the whole animal.
(19) Treatment of rats with phenobarbital or 3-methylcholanthrene increased the rate of conversion of bromoform to CO. Cobaltous chloride treatment of rats or storage of microsomal preparations at 4 degrees C reduced the rate of formation of CO from bromoform.
(20) The ability of carbon tetrabromide, benzyl chloride, bromoform, bromobenzene, carbon tetrachloride, chloroform, dichloromethane, and bromochloromethane to inhibit protein synthesis was correlated with their ability to induce lipid peroxidation, and with their LD50.