(n.) A powerful vegetable alkaloid, found, associated with strychnine, in the seeds of different species of Strychnos, especially in the Nux vomica. It is less powerful than strychnine. Called also brucia and brucina.
Example Sentences:
(1) The strychnine-like effect was common to other glycine-antagonist tested, such as brucine, morphine and laudanosine.
(2) The hyper-irritability elicited by picrotoxin or penicillin G-K was associated with a relatively localized trigger zone in the face, while that elicited by strychnine or brucine spread beyond the trigeminal region to the first cervical dermatome.
(3) In the presence of large amounts of strychnine, brucine is isolated prior to colorimetric analysis by a quantitative thin layer chromatographic technique.
(4) This paper reports the determination of strychnine and brucine in different parts of Semen Strychni (the seeds of Strychnos nux-vomica and S. pierriana), and makes a comparison of the contents between the crude forms and processed products of the two seeds.
(5) Bisnor-dihydrotoxiferine seems to give dichlorometho compounds and N-oxides easily, analogous with strychnine and brucine.
(6) When the effects of quinine, brucine and caffeine on electrical responses in taste cells were examined, they all produced a depolarization associated with an increased input resistance.
(7) Sodium chloride (1,000 mM) enhanced the affinity of strychnine, brucine, isostrychnine, and the nonselective GABA antagonist pitrazepin for [3H]strychnine binding sites, whereas the affinities of glycine, beta-alanine, and taurine were reduced.
(8) The second was developed for the determination of brucine and is based on measuring the intensity of the violet color produced by treating brucine with nitric acid and methanolic stannous chloride.
(9) In contrast, brucine, the 2,3-dimethoxy derivative of strychnine, caused no increase in duplication frequencies under the identical conditions.
(10) The TMA curves of brucine, griseofulvin and phenobarbital were similar to that of indomethacin.
(11) We found that inferior olive lesioned rats had lower threshold to seizures induced by strychnine and brucine, both glycine antagonists.
(12) The natural abundance 13C-NMR spectra of brucine and strychnine were obtained using the pulse Fourier transform technique.
(13) The paper reports the experimental result of the simultaneous quantitative determination of strychnine (ST) and brucine(BR) in Semen Strychni by dual wavelength spectrophotometry.
(14) Nitrate were determined by the brucine method, while nitrates by the Griess colorimetric method.
(15) The CMA was thought to be of L(+)-form based on the results of optical resolution with brucine and also its susceptibility to L(+)-citramalate lyase of Clostridium tetanomorphum.
(16) In vitro, amoxapine and brucine most effectively reversed the inhibitory action of GABA on 35S-TBPS binding.
(17) Binding was completely inhibited by glycine, alanine, alpha-aminobutyric acid, beta-aminoisobutyric acid, hypotaurine and strychnine, and to a lesser extent by 2,2-dimethyl-beta-alanine, brucine and gelsemine.
(18) On heat treatment, the contents of the major alkaloids such as strychnine and brucine declined significantly with increases in the amounts of isostrychnine, isobrucine, strychnine N-oxide and brucine N-oxide.
(19) 5-(3-Hydroxyphenyl)-5-phenylhydantoin (m-HPPH) has been resolved by crystallization of the brucine salts.
(20) Contents of strychnine and brucine in dry seeds of Strychnos nux-vomica and its preparations were determined by gas chromatography.
Brucite
Definition:
(n.) A white, pearly mineral, occurring thin and foliated, like talc, and also fibrous; a native magnesium hydrate.
(n.) The mineral chondrodite.
Example Sentences:
(1) Such manipulation also decreases fiber crystallinity, alters Si-O and Mg-O interlayer bonding, induces coordination changes in the brucite layer, diminishes the ability of fiber to reduce specific free radicals and physisorb organic molecules, and decreases hemolytic potency and antagonist sorption capabilities.
(2) Animals treated with 'brucite' developed moderate levels of pulmonary fibrosis and two carcinomas.
(3) Among these are tremolite and brucite although pure tremolite is also produced commercially in relatively small quantities.
(4) Both tremolite and brucite produced mesotheliomas in greater than 90% of animals following i.p.
(5) However, it was found that the supposedly pure brucite in fact contained 10% chrysotile, a level of contamination that could well have been responsible for the pathological changes found in both inhalation and intraperitoneal injection studies.
(6) In order to determine how harmful commercially exploited tremolite might be in comparison with other asbestos types and to explore the possibility that small amounts of tremolite and brucite as contaminants could significantly affect the pathogenicity of industrially used chrysotile, long-term animal inhalation and injection studies using rats were undertaken with what were considered to be mineralogically pure samples of these minerals.
(7) Mesotheliomata were observed in a considerable proportion of animals with all the samples of asbestos used and with a sample of brucite.