(a.) Of great bulk or dimensions; of great size; large; thick; massive; as, bulky volumes.
Example Sentences:
(1) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(2) In Stage III unilateral nonbulky tumors, the pelvic failure rate was 28% compared with 45% to 50% for unilateral bulky lesions (P = 0.002).
(3) The individual micelles are relatively flat, ring-shaped structures, the center offering space for one of the two bulky sugar chains of the saponins.
(4) We describe the case of a 44 year old woman affected by gastric cancer, who only 10 months after such diagnosis and subsequent total gastrectomy, came to our observation with ascites and bulky peritoneal involvement.
(5) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(6) Thorough bilateral lymphadenectomy can still be performed, but this technique avoids the principal morbidity of this operation except in some patients with bulky disease.
(7) Mammalian tissue DNA has recently been found, via 32P postlabeling, to contain complex profiles of age-dependent bulky carcinogen adductlike covalent modifications, which have been termed I-compounds, referring to their apparent indigenous origin without exposure to exogenous carcinogens.
(8) All of eight patients had relief from bulky intra-abdominal tumors.
(9) The amino-oligopeptidase of the intestinal brush border possesses high specificity for oligopeptides having bulky side chains and is a candidate for a crucial role in the overall assimilation of dietary protein.
(10) Induction with multiagent chemotherapy and radiotherapy to bulky disease-bearing areas (peripheral lymph nodes and mediastinum) was followed by consolidation, CNS prophylaxis, and cyclical remission maintenance therapy.
(11) The staples of the poor consisted of one or two bulky carbohydrate meals (derivatives of different species of cocoyam, cassava, yam and maize) eaten with vegetable soup in palm oil, melon seeds, snail, occasional meat and fish.
(12) In addition, the enzyme exhibits pronounced secondary specificity for a bulky residue, preferentially phenylalanine, in position P2 of substrates.
(13) The safety and efficacy of two devices in producing elevated temperatures in bulky deep tumours was evaluated in 11 patients with 12 tumours.
(14) An individualized approach is warranted, especially when there is an isolated bulky lesion involving the chest wall.
(15) (5) In a recent study of 23 patients undergoing resection of residual nonseminomatous testicular cancer after intensive chemotherapy, 21 had either teratoma in primary tumor or bulky metastatic disease.
(16) Abdominal findings are also similar for the two diseases, with the most common lesions appearing as low attenuation, hypoechoic masses in the solid abdominal organs; ulcerating nodular or diffusely infiltrating bowel lesions; and bulky retroperitoneal, mesenteric, or omental adenopathy.
(17) Biodistribution, imaging, and autoradiographic studies were performed in nude mice transplanted with four different human tumor cell lines to demonstrate the binding of radiolabeled antinuclear monoclonal antibodies within bulky tumors containing necrotic lesions.
(18) One hundred percent concordance between bilateral bulky parametrial involvement and positive pretreatment paraaortic nodes occurred in clinical stage IIIB and IVA patients with metastatic relapse.
(19) Study 1 concerned 667 patients treated in the period 1971-1979 without special measures for mediastinal bulky disease and with four-drug chemotherapy regimens (MOPP, COPP, ABVD) for stage B or IV.
(20) One hundred thirteen were treated at presentation with short courses of chemotherapy, most often with single-agent chlorambucil for bulky stage II and stages III and IV disease.
Burly
Definition:
(a.) Having a large, strong, or gross body; stout; lusty; -- now used chiefly of human beings, but formerly of animals, in the sense of stately or beautiful, and of inanimate things that were huge and bulky.
(a.) Coarse and rough; boisterous.
Example Sentences:
(1) The 12-fluted bur caused no clinically identifiable marks on the enamel surface.
(2) Of roots treated by diamond burs, 165 stained areas were evaluated; 9 (5.5%) exhibited bacteria.
(3) When Bur-tumor was analysed by immunoblotting with Bur-1 antibody a positive reaction was obtained with material migrating in the kD-45kD molecular-weight region.
(4) For the experimental studies, fractures of the jaw bone in terms of oblique osteotomies from angle to sigmoid notch of the mandible of the Malaysian monkeys were made by using #700 fissure bur and reduced and fixed them in terms of interosseous wiring.
(5) Orthopedic new approaches to therapy of OA include removal of abnormal tissue to stimulate repair (e.g., burring, abrasion) and grafting (e.g., osteochondral grafts, perichondrium, periosteum) to the subchondral bone.
(6) In order to establish the complete amino acid sequence of the human IgA alpha1 chain Bur, IgA1 protease from Streptococcus sanguis was employed to generate Fabalpha and Fcalpha fragments in the final stage of this investigation.
(7) Creation of smear layers with abrasive paper or dental burs reduced permeability by 80-85%.
(8) The goal of the present in vivo study was to evaluate human roots by means of scanning electron microscopy (SEM), after treating the root surfaces either with conventional hand instruments or with newly developed diamond burs.
(9) T-shirts were rush-printed overnight, showing his bald, burly head above the logo: "Hi, I'm Joe Plumber and Obama is a punk."
(10) It also was recovered from El Bur and one with similar microscopic characters has been seen in Chad and also in "territoire français des Afars et des Issas".
(11) Moreover a fine diamond bur suitable for air-rotor stripping of posterior interproximal enamel is also described.
(12) In all groups a retrofilling preparation was made to a depth of a number 331 bur.
(13) The highest degree of microleakage was observed when the cavities prepared with a diamond coated bur (mean particle size 80 microns) were left unfinished.
(14) Acceptable finishing procedures for the composite materials tested include silicon carbide disks for accessible areas or 12 fluted finishing burs for more inaccessible areas.
(15) It is hardly suited to the hurly-burly of the hustings.
(16) Some normal cells in the lung, pancreas (acini), and kidney (distal tubules) also bound Bur-1 antibody.
(17) The most active were oak bark, sage and St. John's wort grass WAG extracts, horse radish root and leaf AG extracts, celandine grass WA extract; bur marigold and yarrow grass WA extracts were active towards S. aureus.
(18) I’d called it because of concerns about how we were going to go forwards, particularly on Brexit.” Bur she denied being out of touch in not realising the campaign was not going well.
(19) Method 4 comprised a green stone, a carbide finishing bur, and the Vivadent polisher for composite.
(20) The results of the study lead to the conclusion that criterion for diabetes compensation should be not only the blood sugar normalization bur also the correction of the lipid fractions changes.