(a.) Of great bulk or dimensions; of great size; large; thick; massive; as, bulky volumes.
Example Sentences:
(1) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(2) In Stage III unilateral nonbulky tumors, the pelvic failure rate was 28% compared with 45% to 50% for unilateral bulky lesions (P = 0.002).
(3) The individual micelles are relatively flat, ring-shaped structures, the center offering space for one of the two bulky sugar chains of the saponins.
(4) We describe the case of a 44 year old woman affected by gastric cancer, who only 10 months after such diagnosis and subsequent total gastrectomy, came to our observation with ascites and bulky peritoneal involvement.
(5) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(6) Thorough bilateral lymphadenectomy can still be performed, but this technique avoids the principal morbidity of this operation except in some patients with bulky disease.
(7) Mammalian tissue DNA has recently been found, via 32P postlabeling, to contain complex profiles of age-dependent bulky carcinogen adductlike covalent modifications, which have been termed I-compounds, referring to their apparent indigenous origin without exposure to exogenous carcinogens.
(8) All of eight patients had relief from bulky intra-abdominal tumors.
(9) The amino-oligopeptidase of the intestinal brush border possesses high specificity for oligopeptides having bulky side chains and is a candidate for a crucial role in the overall assimilation of dietary protein.
(10) Induction with multiagent chemotherapy and radiotherapy to bulky disease-bearing areas (peripheral lymph nodes and mediastinum) was followed by consolidation, CNS prophylaxis, and cyclical remission maintenance therapy.
(11) The staples of the poor consisted of one or two bulky carbohydrate meals (derivatives of different species of cocoyam, cassava, yam and maize) eaten with vegetable soup in palm oil, melon seeds, snail, occasional meat and fish.
(12) In addition, the enzyme exhibits pronounced secondary specificity for a bulky residue, preferentially phenylalanine, in position P2 of substrates.
(13) The safety and efficacy of two devices in producing elevated temperatures in bulky deep tumours was evaluated in 11 patients with 12 tumours.
(14) An individualized approach is warranted, especially when there is an isolated bulky lesion involving the chest wall.
(15) (5) In a recent study of 23 patients undergoing resection of residual nonseminomatous testicular cancer after intensive chemotherapy, 21 had either teratoma in primary tumor or bulky metastatic disease.
(16) Abdominal findings are also similar for the two diseases, with the most common lesions appearing as low attenuation, hypoechoic masses in the solid abdominal organs; ulcerating nodular or diffusely infiltrating bowel lesions; and bulky retroperitoneal, mesenteric, or omental adenopathy.
(17) Biodistribution, imaging, and autoradiographic studies were performed in nude mice transplanted with four different human tumor cell lines to demonstrate the binding of radiolabeled antinuclear monoclonal antibodies within bulky tumors containing necrotic lesions.
(18) One hundred percent concordance between bilateral bulky parametrial involvement and positive pretreatment paraaortic nodes occurred in clinical stage IIIB and IVA patients with metastatic relapse.
(19) Study 1 concerned 667 patients treated in the period 1971-1979 without special measures for mediastinal bulky disease and with four-drug chemotherapy regimens (MOPP, COPP, ABVD) for stage B or IV.
(20) One hundred thirteen were treated at presentation with short courses of chemotherapy, most often with single-agent chlorambucil for bulky stage II and stages III and IV disease.
Chunky
Definition:
(a.) Short and thick.
Example Sentences:
(1) The invaginations were classified into four easily recognized types: regular, chunky, filigree, and ridge (present only in axon hillock regions).
(2) Rolls-Royce, which is owned by the German carmaker BMW , said demand had been strong for the Wraith, a chunky, gas-guzzling two-door car priced at more than £210,000.
(3) Capote clearly identified with this "chunky, misshapen child-man".
(4) The trick is that the service will run, not along thin telephone fibres, but chunky electricity cable, a centimetre thick.
(5) A Nestlé Kit Kat Chunky Collection Giant Egg was advertised at £7.49 for 10 days in January this year at Ocado, then sold on offer at £5 for 51 days.
(6) Some have voices so wispy that they are indistinguishable from the chunky backing tracks and others seem to have never been able to pick out a tune in their life.
(7) Both measures are now showing chunky rises, with the claimant count up by 37,100 between June and July, and the LFS measure rising by 38,000 in the three months to June.
(8) US Treasuries have also strengthened, driving down yields on America's 10-year bonds by a chunky 8 basis points to 2.812% , from 2.9% on Friday.
(9) Over the next year the sequence of events is likely to be growing recessionary pressure leading to weaker inflationary pressure, prompting chunky falls in interest rates.
(10) I had meetings with all sorts of people and I'm going up for roles that are so chunky so …" he pauses for a minute and apologises for getting too passionate.
(11) A chunky piece of ugly technology, the sobriety bracelet is used to detect even a smidgen of alcohol in the perspiration of its wearer, from whom readings are sent twice a day in order to monitor their abstinence.
(12) Perhaps it was because, despite being the first portable music player, it wasn't as easy to lug around as the MP3 player; its chunky dimensions compelled it to be worn clipped to a belt, creating the danger that it would unclip itself – which it did with obnoxious regularity – and crash to the ground, disgorging its batteries.
(13) Previous star performers such as Sports Direct and Associated British Foods are being hit hard... Retail was one of the best-performing sectors in the first quarter, but the result of this was that many names were trading at chunky valuations, making them vulnerable to any momentum-driven selloff.
(14) When I buy my copy of the Observer on a Sunday I realise what a wonderfully chunky product it is."
(15) Facebook Twitter Pinterest The Moto 360 beside the Samsung Gear Live Photograph: Samuel Gibbs for the Guardian On the wrist it looks much more like a traditional watch than a smartwatch, about the size of a chunky man’s watch though much lighter and smaller than the Gear Live.
(16) For anyone trying to work out the Venn diagram of iconic protest imagery, three tropes will immediately jump to the fore: the quiet dignity of said woman; the battle-hungry paraphernalia of male authority (your shields and batons and chunky uniforms); and the dramatic flip of power that clash presents.
(17) Pakistan boasted a supine and notably chunky Shoaib Akhtar.
(18) However, learning to play and master any of these games is a significant feat, despite their chunky aesthetics.
(19) While the effect had Anderson’s signature androgynous look, and a retro feel, bi-coloured sweaters, cropped shearling jackets and chunky scarves showed him moving gently towards more wearable pieces.
(20) The chunky boxers and smooth animation made for impressive fight scenes.