(a.) Of great bulk or dimensions; of great size; large; thick; massive; as, bulky volumes.
Example Sentences:
(1) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(2) In Stage III unilateral nonbulky tumors, the pelvic failure rate was 28% compared with 45% to 50% for unilateral bulky lesions (P = 0.002).
(3) The individual micelles are relatively flat, ring-shaped structures, the center offering space for one of the two bulky sugar chains of the saponins.
(4) We describe the case of a 44 year old woman affected by gastric cancer, who only 10 months after such diagnosis and subsequent total gastrectomy, came to our observation with ascites and bulky peritoneal involvement.
(5) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(6) Thorough bilateral lymphadenectomy can still be performed, but this technique avoids the principal morbidity of this operation except in some patients with bulky disease.
(7) Mammalian tissue DNA has recently been found, via 32P postlabeling, to contain complex profiles of age-dependent bulky carcinogen adductlike covalent modifications, which have been termed I-compounds, referring to their apparent indigenous origin without exposure to exogenous carcinogens.
(8) All of eight patients had relief from bulky intra-abdominal tumors.
(9) The amino-oligopeptidase of the intestinal brush border possesses high specificity for oligopeptides having bulky side chains and is a candidate for a crucial role in the overall assimilation of dietary protein.
(10) Induction with multiagent chemotherapy and radiotherapy to bulky disease-bearing areas (peripheral lymph nodes and mediastinum) was followed by consolidation, CNS prophylaxis, and cyclical remission maintenance therapy.
(11) The staples of the poor consisted of one or two bulky carbohydrate meals (derivatives of different species of cocoyam, cassava, yam and maize) eaten with vegetable soup in palm oil, melon seeds, snail, occasional meat and fish.
(12) In addition, the enzyme exhibits pronounced secondary specificity for a bulky residue, preferentially phenylalanine, in position P2 of substrates.
(13) The safety and efficacy of two devices in producing elevated temperatures in bulky deep tumours was evaluated in 11 patients with 12 tumours.
(14) An individualized approach is warranted, especially when there is an isolated bulky lesion involving the chest wall.
(15) (5) In a recent study of 23 patients undergoing resection of residual nonseminomatous testicular cancer after intensive chemotherapy, 21 had either teratoma in primary tumor or bulky metastatic disease.
(16) Abdominal findings are also similar for the two diseases, with the most common lesions appearing as low attenuation, hypoechoic masses in the solid abdominal organs; ulcerating nodular or diffusely infiltrating bowel lesions; and bulky retroperitoneal, mesenteric, or omental adenopathy.
(17) Biodistribution, imaging, and autoradiographic studies were performed in nude mice transplanted with four different human tumor cell lines to demonstrate the binding of radiolabeled antinuclear monoclonal antibodies within bulky tumors containing necrotic lesions.
(18) One hundred percent concordance between bilateral bulky parametrial involvement and positive pretreatment paraaortic nodes occurred in clinical stage IIIB and IVA patients with metastatic relapse.
(19) Study 1 concerned 667 patients treated in the period 1971-1979 without special measures for mediastinal bulky disease and with four-drug chemotherapy regimens (MOPP, COPP, ABVD) for stage B or IV.
(20) One hundred thirteen were treated at presentation with short courses of chemotherapy, most often with single-agent chlorambucil for bulky stage II and stages III and IV disease.
Gross
Definition:
(superl.) Great; large; bulky; fat; of huge size; excessively large.
(superl.) Coarse; rough; not fine or delicate.
(superl.) Not easily aroused or excited; not sensitive in perception or feeling; dull; witless.
(superl.) Expressing, Or originating in, animal or sensual appetites; hence, coarse, vulgar, low, obscene, or impure.
(superl.) Thick; dense; not attenuated; as, a gross medium.
(superl.) Whole; entire; total; without deduction; as, the gross sum, or gross amount, the gross weight; -- opposed to net.
(a.) The main body; the chief part, bulk, or mass.
(sing. & pl.) The number of twelve dozen; twelve times twelve; as, a gross of bottles; ten gross of pens.
Example Sentences:
(1) Gross brain atrophy was slight and equal in both groups.
(2) Gross deformity, point tenderness and decrease in supination and pronation movements of the forearm were the best predictors of bony injury.
(3) Gross mortgage lending stood at £7.9bn in April compared with £8.7bn in March and a six-month average of £9.9bn.
(4) But that gross margin only includes the cost of paying drivers as a cost of revenue, classifying everything else, such as operations, R&D, and sales and marketing, as “operating expenses”.
(5) Initial analysis suggests that about one-fifth of gross costs would be directly returned to the public purse via income tax and national insurance payments.
(6) The concentration of potassium (K+) and sodium (Na+) was measured in breast cyst fluid (BCF) from 611 cysts greater than 3 ml aspirated in 520 women with gross cystic disease of the breast.
(7) They also questioned why George Osborne and the Treasury failed to realise there was a potential issue earlier in the calculation process – pointing to recent upwards revisions of post-1995 gross national income by the UK’s own statistics watchdog.
(8) A lost generation of 14 million out-of-work and disengaged young Europeans is costing member states a total of €153bn (£124bn) a year – 1.2% of the EU's gross domestic product – the largest study of the young unemployed has concluded.
(9) It's the roughly $2bn in revenue grossed by his blockbuster movies, some of which he had to be talked into making.
(10) Ender nails as well as three forms of interlocking nails, Brooker-Wills (B-W), Klenm-Schellman (K-S), and Grosse-Kempf (G-K), were implanted in cadaver femora.
(11) The loss of muscarinic and the sparing of benzodiazepine receptors occurs in the temporal cortex of histologically normal brains in the absence of significant atrophy and of gross dementia.
(12) Affected individuals were not clinically photosensitive, but their fibroblasts demonstrated gross cytopathic changes, low survival indices and an increased frequency of DNA single strand breaks following exposure to long-wave ultraviolet radiation (UVA).
(13) Fields said: "The assertions that Tom Cruise likened making a movie to being at war in Afghanistan is a gross distortion of the record... What Tom said, laughingly, was that sometimes, 'That's what it feels like.'"
(14) A tumor measuring 20 x 25 mm was recognized upon gross examination in the upper lobe of the right lung.
(15) No gross toxicological effects were noted in the experimental fish, although their weight gain was less than that of the controls.
(16) Currently, entitlement to CTC for families with one to three children is fully exhausted when gross household earnings reach about £26,000 and £40,000 a year respectively.
(17) There were no differences in the distribution of gross and histological types of cancer in the modes of recurrence.
(18) The pigeon's metapatagialis muscle consists of three slips, two twitch and one tonic, and these slips are distinguishable at the gross anatomical level.
(19) These findings were confirmed by examination of the experimental cases on the basis of the gross diameter of the warts.
(20) Gross examination suggested that TD was present in 80 per cent, 79 per cent and 27 per cent of tibiotarsi from birds on diets 1, 2 and 4, respectively.