(a.) Of great bulk or dimensions; of great size; large; thick; massive; as, bulky volumes.
Example Sentences:
(1) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(2) In Stage III unilateral nonbulky tumors, the pelvic failure rate was 28% compared with 45% to 50% for unilateral bulky lesions (P = 0.002).
(3) The individual micelles are relatively flat, ring-shaped structures, the center offering space for one of the two bulky sugar chains of the saponins.
(4) We describe the case of a 44 year old woman affected by gastric cancer, who only 10 months after such diagnosis and subsequent total gastrectomy, came to our observation with ascites and bulky peritoneal involvement.
(5) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(6) Thorough bilateral lymphadenectomy can still be performed, but this technique avoids the principal morbidity of this operation except in some patients with bulky disease.
(7) Mammalian tissue DNA has recently been found, via 32P postlabeling, to contain complex profiles of age-dependent bulky carcinogen adductlike covalent modifications, which have been termed I-compounds, referring to their apparent indigenous origin without exposure to exogenous carcinogens.
(8) All of eight patients had relief from bulky intra-abdominal tumors.
(9) The amino-oligopeptidase of the intestinal brush border possesses high specificity for oligopeptides having bulky side chains and is a candidate for a crucial role in the overall assimilation of dietary protein.
(10) Induction with multiagent chemotherapy and radiotherapy to bulky disease-bearing areas (peripheral lymph nodes and mediastinum) was followed by consolidation, CNS prophylaxis, and cyclical remission maintenance therapy.
(11) The staples of the poor consisted of one or two bulky carbohydrate meals (derivatives of different species of cocoyam, cassava, yam and maize) eaten with vegetable soup in palm oil, melon seeds, snail, occasional meat and fish.
(12) In addition, the enzyme exhibits pronounced secondary specificity for a bulky residue, preferentially phenylalanine, in position P2 of substrates.
(13) The safety and efficacy of two devices in producing elevated temperatures in bulky deep tumours was evaluated in 11 patients with 12 tumours.
(14) An individualized approach is warranted, especially when there is an isolated bulky lesion involving the chest wall.
(15) (5) In a recent study of 23 patients undergoing resection of residual nonseminomatous testicular cancer after intensive chemotherapy, 21 had either teratoma in primary tumor or bulky metastatic disease.
(16) Abdominal findings are also similar for the two diseases, with the most common lesions appearing as low attenuation, hypoechoic masses in the solid abdominal organs; ulcerating nodular or diffusely infiltrating bowel lesions; and bulky retroperitoneal, mesenteric, or omental adenopathy.
(17) Biodistribution, imaging, and autoradiographic studies were performed in nude mice transplanted with four different human tumor cell lines to demonstrate the binding of radiolabeled antinuclear monoclonal antibodies within bulky tumors containing necrotic lesions.
(18) One hundred percent concordance between bilateral bulky parametrial involvement and positive pretreatment paraaortic nodes occurred in clinical stage IIIB and IVA patients with metastatic relapse.
(19) Study 1 concerned 667 patients treated in the period 1971-1979 without special measures for mediastinal bulky disease and with four-drug chemotherapy regimens (MOPP, COPP, ABVD) for stage B or IV.
(20) One hundred thirteen were treated at presentation with short courses of chemotherapy, most often with single-agent chlorambucil for bulky stage II and stages III and IV disease.
Lumping
Definition:
(p. pr. & vb. n.) of Lump
(a.) Bulky; heavy.
Example Sentences:
(1) Although distributed models yielded improved fits of the data, the distributed and lumped models produced similar estimates of membrane parameters.
(2) Part of his initial lump sum will be donated to a fund to replace a hall destroyed by fire in an arson attack four years ago at St Luke’s Church in Newton Poppleford.
(3) Can somebody who is not a billionaire, who stands for working families, actually win an election into which billionaires are pouring millions of dollars?” Naming prominent and controversial rightwing donors, he said: “It is not just Hillary, it is the Koch brothers, it is Sheldon Adelson.” Stephanopoulos seized the moment, asking: “Are you lumping her in with them?” Choosing to refer to the 2010 supreme court decision that removed limits on corporate political donations, rather than address the question directly, Sanders replied: “What I am saying is that I get very frightened about the future of American democracy when this becomes a battle between billionaires.
(4) In agreement with the predictions based on a simple lumped-parameters model, we found that Z reached very low values, especially at the frequencies where H had a resonance peak.
(5) The effective electrical geometry under the conditions of control and 0.5 mM PNB sufficient to completely abolish the postsynaptic potential were determined from analyses of the membrane charging curves assuming the lumped-soma-short-cable model.
(6) Examination of the patient revealed 2 lumps detected in the right hemi-scrotum which felt like small testes and did not permit transillumination.
(7) Relief on contributions, national insurance, tax-exempt lump sums and others amounts to a phenomenal £48.4bn a year.
(8) If the abnormal sensation, such as a lump or choking, in the throat was mainly caused by inflammatory changes in the palatine tonsils or their surrounding tissues and conveyed via vagal nerve branches distributing there, the sensation might be reduced by topically injected Impletol (Procaine and caffeine in saline solution), i.e.
(9) Combination with IP degrees increases polyhead formation when head formation is not blocked at a more defective stage but results in a qualitative shift to lump formation in association with gene 22 mutants.
(10) "It really gets my goat when commentators (literally all British ones especially Townsend) complain that Spain don't play with a striker as they 'lack a focal point' or 'don't have any direction', presumably because these commentators would lump it up to the 'big man'.
(11) The degree of observer variation in recording 11 186 items of clinical data from 242 woman who presented complaining of a lump in the breast to a group of 10 surgeons was studied.
(12) It is therefore felt that (1) a cautious attitude is necessary when commenting on FNAC samples until more specific criteria are forthcoming for the diagnosis of this neoplasm; and (2) if cellular atypias are seen in FNAC samples, these should be reported with a recommendation for removal of the breast lump and a detailed tissue examination.
(13) Our analysis of 1051 breast biopsies in West Indian women under the age of 30 y revealed that 99% of the breast lumps were benign.
(14) Kadyrov also gave the happy couple an unusual wedding present – "a five kilo lump of gold".
(15) A female patient presented with a lump in the right parotedeal region.
(16) GCPP includes standardization of both experimental factors (lumped constant, arterialization, purity of tracer, regions of interest, relative rates) and clinical factors (state of the subject, wakefulness, anxiety, gender, course of the disease) in PET performance.
(17) There are clearly lots of nice, benign, kind nuns who'd be a bit miffed to be lumped in with all the others."
(18) The rest of ICD-10, either on the three- or on the four-digit level, has to be grouped into combinations of classes (lumping) to allow compatible conversion to the remaining rubrics of ICPC.
(19) His BBC television career famously came to an end when he thrust a lump of cheese in his commissioning editor's face .
(20) A 39-year-old woman was admitted to our hospital complaining of large breast lump (11.5 X 8.0 cm) and an abnormal nipple discharge.