(a.) Of great bulk or dimensions; of great size; large; thick; massive; as, bulky volumes.
Example Sentences:
(1) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(2) In Stage III unilateral nonbulky tumors, the pelvic failure rate was 28% compared with 45% to 50% for unilateral bulky lesions (P = 0.002).
(3) The individual micelles are relatively flat, ring-shaped structures, the center offering space for one of the two bulky sugar chains of the saponins.
(4) We describe the case of a 44 year old woman affected by gastric cancer, who only 10 months after such diagnosis and subsequent total gastrectomy, came to our observation with ascites and bulky peritoneal involvement.
(5) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(6) Thorough bilateral lymphadenectomy can still be performed, but this technique avoids the principal morbidity of this operation except in some patients with bulky disease.
(7) Mammalian tissue DNA has recently been found, via 32P postlabeling, to contain complex profiles of age-dependent bulky carcinogen adductlike covalent modifications, which have been termed I-compounds, referring to their apparent indigenous origin without exposure to exogenous carcinogens.
(8) All of eight patients had relief from bulky intra-abdominal tumors.
(9) The amino-oligopeptidase of the intestinal brush border possesses high specificity for oligopeptides having bulky side chains and is a candidate for a crucial role in the overall assimilation of dietary protein.
(10) Induction with multiagent chemotherapy and radiotherapy to bulky disease-bearing areas (peripheral lymph nodes and mediastinum) was followed by consolidation, CNS prophylaxis, and cyclical remission maintenance therapy.
(11) The staples of the poor consisted of one or two bulky carbohydrate meals (derivatives of different species of cocoyam, cassava, yam and maize) eaten with vegetable soup in palm oil, melon seeds, snail, occasional meat and fish.
(12) In addition, the enzyme exhibits pronounced secondary specificity for a bulky residue, preferentially phenylalanine, in position P2 of substrates.
(13) The safety and efficacy of two devices in producing elevated temperatures in bulky deep tumours was evaluated in 11 patients with 12 tumours.
(14) An individualized approach is warranted, especially when there is an isolated bulky lesion involving the chest wall.
(15) (5) In a recent study of 23 patients undergoing resection of residual nonseminomatous testicular cancer after intensive chemotherapy, 21 had either teratoma in primary tumor or bulky metastatic disease.
(16) Abdominal findings are also similar for the two diseases, with the most common lesions appearing as low attenuation, hypoechoic masses in the solid abdominal organs; ulcerating nodular or diffusely infiltrating bowel lesions; and bulky retroperitoneal, mesenteric, or omental adenopathy.
(17) Biodistribution, imaging, and autoradiographic studies were performed in nude mice transplanted with four different human tumor cell lines to demonstrate the binding of radiolabeled antinuclear monoclonal antibodies within bulky tumors containing necrotic lesions.
(18) One hundred percent concordance between bilateral bulky parametrial involvement and positive pretreatment paraaortic nodes occurred in clinical stage IIIB and IVA patients with metastatic relapse.
(19) Study 1 concerned 667 patients treated in the period 1971-1979 without special measures for mediastinal bulky disease and with four-drug chemotherapy regimens (MOPP, COPP, ABVD) for stage B or IV.
(20) One hundred thirteen were treated at presentation with short courses of chemotherapy, most often with single-agent chlorambucil for bulky stage II and stages III and IV disease.
Meaty
Definition:
(a.) Abounding in meat.
Example Sentences:
(1) Perisic darts in from the edge of the penalty area to get on the end of it and thumps a meaty header wide.
(2) On average, monosodium glutamate and seltzer, which mongrel dogs do not normally encounter in their diets, produced lower gastric acid secretion and pancreatic polypeptide release than sweet, sour, salty, bitter, and meaty tastes.
(3) Each prominent character has been given meaty storylines to gorge on, and while some haven’t panned out quite as well as others (Jimmy’s sideline as a sex worker was introduced and wisely dropped, as was an ill-advised plot-strand about drug-induced rape), the web of intrigue that’s been constructed so far doesn’t have any major weaknesses in it at all.
(4) Nordestinos brought their hearty, meaty peasant cuisine with them, and one former factory worker, Jose Oliveira de Almeid, called simply Seu Ze, opened a small restaurant called Mocotó in the working-class suburb of Villa Medeiros.
(5) 9.47pm GMT 88 min: … but it's flicked up and lands safely in the comfortingly meaty hands of Lloris.
(6) There are 30 new weapons, including a new class of marksman rifles; Perks now have a points system, allowing you to buy several weaker options or opt for one or two really meaty specials.
(7) 2.37pm BST 31 mins Ivanovic has just stuck a meaty challenge in on Suárez.
(8) Nick Clegg plans to devote a meaty chunk of his leader's speech to listing all the things he has blocked the Tories from doing.
(9) The meaty melodies are provided by John Squire, pinning down the guitar surging from caustic feedback to ecstatic wah-wah chugging – all in the space of a song.
(10) Rory Fallon rises highest and heads clear with a mighty meaty meeting of forehead and Jabulani.
(11) We report on 2 unrelated boys with a distinctive facial appearance of microtia, atretic external auditory meati, small mandible, and microstomia, who also have a skeletal dysplasia, microcephaly, and joint contractures.
(12) Photograph: Susi Smither A meaty, warming robust meal to get you through the last of the cold spring days.
(13) They are characterised by psychomotor retardation, short stature, narrowing of the external auditory meati and abnormalities of the digits.
(14) Ordering a procession of dishes to share over a long afternoon's grazing is the perfect way to go here: try crunchy cubes of fried tapioca with a sweet and spicy dipping sauce, and out-of-this-world torresmo (meaty, homemade pork scratchings, £1.30).
(15) She went for her shots, meaty, buffeting groundstrokes, right from the start and knocked Williams out of her normally commanding stride.
(16) He's a man of mellowness, not ego – far from bitter at the lack of meaty roles, just gently getting on with what he's offered.
(17) And there were a couple of meaty reforms – raising the personal tax allowance; cutting corporation tax.
(18) Miliband's more detailed thoughts on reforming company laws are a little more meaty, but still sketch no more than the first few marks on a blank sheet.
(19) Men in professional kitchens all over the world, whether they are cooking big, meaty dishes, or tweezering edible micro flowers on to oysters, salivate over getting a dish just so, and appear to take it far more seriously than most female professional chefs and cooks.
(20) Steven Gerrard intervenes and retrieves possession for Liverpool with a meaty challenge.