(a.) Of great bulk or dimensions; of great size; large; thick; massive; as, bulky volumes.
Example Sentences:
(1) Survival was independent of the type of clinical presentation and protocol employed but was correlated with the stage (P less than 0.0005), symptoms (P less than 0.025), bulky disease (P less than 0.025) and bone marrow involvement (P less than 0.025).
(2) In Stage III unilateral nonbulky tumors, the pelvic failure rate was 28% compared with 45% to 50% for unilateral bulky lesions (P = 0.002).
(3) The individual micelles are relatively flat, ring-shaped structures, the center offering space for one of the two bulky sugar chains of the saponins.
(4) We describe the case of a 44 year old woman affected by gastric cancer, who only 10 months after such diagnosis and subsequent total gastrectomy, came to our observation with ascites and bulky peritoneal involvement.
(5) The estrogen receptor seems to have a moderate tolerance for bulky substituents: All of the halogen and halomethyl substituents bind with an affinity at least 50% that of estradiol; in the three atom alkyl series, the affinity declined markedly from propargyl (44%) and allyl (38%) to propyl (5%), suggestive of detailed steric constraints or a preference for unsaturation.
(6) Thorough bilateral lymphadenectomy can still be performed, but this technique avoids the principal morbidity of this operation except in some patients with bulky disease.
(7) Mammalian tissue DNA has recently been found, via 32P postlabeling, to contain complex profiles of age-dependent bulky carcinogen adductlike covalent modifications, which have been termed I-compounds, referring to their apparent indigenous origin without exposure to exogenous carcinogens.
(8) All of eight patients had relief from bulky intra-abdominal tumors.
(9) The amino-oligopeptidase of the intestinal brush border possesses high specificity for oligopeptides having bulky side chains and is a candidate for a crucial role in the overall assimilation of dietary protein.
(10) Induction with multiagent chemotherapy and radiotherapy to bulky disease-bearing areas (peripheral lymph nodes and mediastinum) was followed by consolidation, CNS prophylaxis, and cyclical remission maintenance therapy.
(11) The staples of the poor consisted of one or two bulky carbohydrate meals (derivatives of different species of cocoyam, cassava, yam and maize) eaten with vegetable soup in palm oil, melon seeds, snail, occasional meat and fish.
(12) In addition, the enzyme exhibits pronounced secondary specificity for a bulky residue, preferentially phenylalanine, in position P2 of substrates.
(13) The safety and efficacy of two devices in producing elevated temperatures in bulky deep tumours was evaluated in 11 patients with 12 tumours.
(14) An individualized approach is warranted, especially when there is an isolated bulky lesion involving the chest wall.
(15) (5) In a recent study of 23 patients undergoing resection of residual nonseminomatous testicular cancer after intensive chemotherapy, 21 had either teratoma in primary tumor or bulky metastatic disease.
(16) Abdominal findings are also similar for the two diseases, with the most common lesions appearing as low attenuation, hypoechoic masses in the solid abdominal organs; ulcerating nodular or diffusely infiltrating bowel lesions; and bulky retroperitoneal, mesenteric, or omental adenopathy.
(17) Biodistribution, imaging, and autoradiographic studies were performed in nude mice transplanted with four different human tumor cell lines to demonstrate the binding of radiolabeled antinuclear monoclonal antibodies within bulky tumors containing necrotic lesions.
(18) One hundred percent concordance between bilateral bulky parametrial involvement and positive pretreatment paraaortic nodes occurred in clinical stage IIIB and IVA patients with metastatic relapse.
(19) Study 1 concerned 667 patients treated in the period 1971-1979 without special measures for mediastinal bulky disease and with four-drug chemotherapy regimens (MOPP, COPP, ABVD) for stage B or IV.
(20) One hundred thirteen were treated at presentation with short courses of chemotherapy, most often with single-agent chlorambucil for bulky stage II and stages III and IV disease.
(a.) A light two-wheeled carriage for a single person.
Example Sentences:
(1) This 90s pop confection had torn tights, a sulky attitude and high regard for Quentin Tarantino.
(2) As soon as I called them and was like, 'Hey guys, it's OK, I'm not smoking meth or anything,' it was OK." He adds, frowning: "I don't really know why it happened… My girlfriend told me everyone had been saying, [he puts on a sulky voice] 'Man, Mac's shows aren't crazy any more.'
(3) It's the first interview he's done since his marriage and divorce and the split-up of the Ordinary Boys, and it all comes rushing out in a spate, a tangle of chronological confusions and jokes, and groans when I quote some of his old interviews back at him, and statements of contrition, and digressions about Dawkins or whatever, and here's the confounding thing - he's really nothing like I was expecting, not indie-boy sulky, or attempting to play it cool, he's just talkative and engaging, and he has a sense of humour about himself that, from reading his previous interviews, I wouldn't have even guessed at.
(4) The sulky teenager has, in fact, got it slightly wrong: the family tradition is to be impregnated by the landlord of the Queen Vic – not, as in this case, the landlord's little brother.
(5) The Mirror also said that even Clarkson’s “most sulky fans” should find a lot to like about the show after his departure and the Telegraph welcomed Evans and co’s conservative approach.
(6) In the horse-related fatalities, the most common cause of accident was that the horse bolted or reared, causing the rider to fall off the horse or the cart or sulky.
(7) Updated at 7.45pm BST 7.35pm BST Asked on ITV about his pre-match team-talk, Mourinho reveals that he's giving his side the sulky wife treatment: "No words ... my silence is a good way for them to understand how I feel".
(8) Only rarely do we see a gem such as the glorious Quentin Tarantino interview, where he shouted at Krishnan Guru-Murthy : “I’m shutting your butt down!” As a rule, in print media, it’s your word against theirs regarding any sulky, ill-mannered, ball-stabbing shenanigans.
(9) This isn't the charming hero we're used to seeing Pitt play; he's jowly and sulky and racked with a sense of failure, a threatening and disciplinarian family presence.
(10) In a small room off the tunnel at Wycombe’s ground, as a tea urn belched steam into the freezing January air, he bemoaned, in his characteristically sulky way, a recruitment policy that had left him overburdened with attacking players but bereft of defensive cover.
(11) Brando was Johnny the biker in The Wild One (1953), a very camp figure, a gay icon, but a sulky kid who, when asked "What are you rebelling against?
(12) But in the case of Sulky Batman 3.0, it's way too po-faced.
(13) That sounds like a full-time job to me – try employing your sulky teenager or dog to do it for you.
(14) All those years spent in the dark, believing that colleagues were putting up with that sulky sourness in order to squeeze every moment from the day.
(15) The styles of the two men could not be more different – Ford's emotional careering from sulkiness to rage could not look more different, on TV at least, from Harper's gently superior thin-lipped smile.
(16) The meeting followed a four-year mutual sulky silence prompted by what Peter may (or may not) have said about Christopher being a Stalinist.
(17) Catch-22's author was then a sulky, ill-tempered 37-year old advertising executive in New York, who had thick, short, curly hair, a strong chin and a fleshy nose.
(18) When did your sweetpea become a massive sulky thing?
(19) It could be that their elimination is a liberation and they return to the free-flowing style of qualifying but the mood after the defeat by Nigeria was one of sulkiness and disaffection.