(n.) That which is borne with labor or difficulty; that which is grievous, wearisome, or oppressive.
(n.) The capacity of a vessel, or the weight of cargo that she will carry; as, a ship of a hundred tons burden.
(n.) The tops or heads of stream-work which lie over the stream of tin.
(n.) The proportion of ore and flux to fuel, in the charge of a blast furnace.
(n.) A fixed quantity of certain commodities; as, a burden of gad steel, 120 pounds.
(n.) A birth.
(v. t.) To encumber with weight (literal or figurative); to lay a heavy load upon; to load.
(v. t.) To oppress with anything grievous or trying; to overload; as, to burden a nation with taxes.
(v. t.) To impose, as a load or burden; to lay or place as a burden (something heavy or objectionable).
(n.) The verse repeated in a song, or the return of the theme at the end of each stanza; the chorus; refrain. Hence: That which is often repeated or which is dwelt upon; the main topic; as, the burden of a prayer.
(n.) The drone of a bagpipe.
(n.) A club.
Example Sentences:
(1) Senator Bernie Sanders of Vermont, who is also seeking the Democratic presidential nomination, recently proposed a bill that would ease the financial burden of prescription drugs on elderly Americans by allowing Medicare, the national social health insurance program, to negotiate with the pharmaceutical companies to keep prices down.
(2) Finally, before the advent of the third-party payment, operations were avoided because of the financial burden.
(3) However, civil society groups have raised concerns about the ethics of providing ‘climate loans’ which increase the country’s debt burden.
(4) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
(5) Economic burdens for postmarketing research should be shared jointly by the research-oriented and generic drug companies.
(6) There is general agreement that suicides are likely to be undercounted, both for structural reasons (the burden-of-proof issue, the requirement that the coroner or medical examiner suspect the possibility of suicide) and for sociocultural reasons.
(7) The art Kennard produced formed the basis of his career, as he recounted later: “I studied as a painter, but after the events of 1968 I began to look for a form of expression that could bring art and politics together to a wider audience … I found that photography wasn’t as burdened with similar art historical associations.” The result was his STOP montage series.
(8) The analysis indicated a high cost burden for families in all disease categories studied, although a lack of uniformity in data presentation and in the variables studied prevented specific generalizations to be made about the numbers or characteristics of families with high costs.
(9) "Public servants did nothing to cause the slump but are being asked to bear an unfair share of the burden.
(10) The irony of this type of self-manipulation is that ultimately the child, or adult, finds himself again burdened by impotence, though it is the impotence of guilt rather than that of shame.
(11) The aim of the study was to find whether treatment would result in an improvement of cognition, of functioning in daily life, decrease of behavioural disturbances, and decrease in burden experienced by the carers.
(12) Lymph proliferative disorders with a high mitotic rate, and large tumor burden, regardless of histologic features, should be treated prophylactically against tumor lysis if regrowth between cycles occurs.
(13) These data indicate that, compared with animals at sea level, animals at altitude have an increased body burden of COHb and will attain the COHb level associated with the National Ambient Air Quality Standard for CO more quickly when breathing CO.
(14) Macro-epidemiology is concerned with the absolute and relative contributions of particular causes or diseases to the overall burden of ill-health in a population.
(15) Communicable diseases represent a considerable burden in terms of suffering and costs.
(16) This is indirect evidence suggesting that mercury from dental amalgam fillings may contribute to the body burden of mercury in the brain.
(17) The gender-specific kinship relationship of patients and their care providers has not generally been investigated in studies of caregiver burden and well-being.
(18) In predicting response to therapy, poor prognostic factors included large tumor burdens, advanced disease stage, and chemotherapy-resistant tumors.
(19) Radical postoperative irradiation (A) is burdened by 3 serious complications and a considerably higher amount of complaints.
(20) MMC and 5-FU did not show significant activity against large tumor burden, while a relatively good activity was detected in patients with minimal disease.
Saddle
Definition:
(n.) A seat for a rider, -- usually made of leather, padded to span comfortably a horse's back, furnished with stirrups for the rider's feet to rest in, and fastened in place with a girth; also, a seat for the rider on a bicycle or tricycle.
(n.) A padded part of a harness which is worn on a horse's back, being fastened in place with a girth. It serves various purposes, as to keep the breeching in place, carry guides for the reins, etc.
(n.) A piece of meat containing a part of the backbone of an animal with the ribs on each side; as, a saddle of mutton, of venison, etc.
(n.) A block of wood, usually fastened to some spar, and shaped to receive the end of another spar.
(n.) A part, as a flange, which is hollowed out to fit upon a convex surface and serve as a means of attachment or support.
(n.) The clitellus of an earthworm.
(n.) The threshold of a door, when a separate piece from the floor or landing; -- so called because it spans and covers the joint between two floors.
(v. t.) To put a saddle upon; to equip (a beast) for riding.
(v. t.) Hence: To fix as a charge or burden upon; to load; to encumber; as, to saddle a town with the expense of bridges and highways.
Example Sentences:
(1) Based on our experience with the mark I prosthesis we have designed and developed a mark II model which has freedom of axial rotation of the saddle.
(2) Joaquin Rodriguez Oliver is amusing himself by trying to take a puff of a cigar in his saddle.
(3) To date, 3-dimensional studies have demonstrated that the mitral valve is saddle-shaped in systole, so that apparent superior leaflet displacement in the mediolateral 4-chamber view, often seen in otherwise normal individuals, lies entirely within the bounds defined by the mitral annulus and occurs without leaflet distortion or actual displacement above the entire mitral valve.
(4) Devitalized homologous costal cartilage is widely employed as an implant in the management of the saddle nose.
(5) Our practice of initiating treatment of saddle embolism with immediate systemic heparin infusion resembles that of Blaisdell et al.
(6) Charlize Theron is set to star opposite Seth MacFarlane in the Ted creator's new comedy western A Million Ways to Die in the West, tipped as a homage to Mel Brooks's classic movie Blazing Saddles .
(7) Eleven patients with stones overlying the sacro-iliac joint were treated in the prone position, while 56 patients with stones distal to the sacro-iliac joint, were treated in the saddle (astride) position.
(8) Proteins of normal serum as well as induced serum emerged in two peaks separated by a deep saddle.
(9) In the Russian gallery, for example, the courageous Vadim Zakharov presents a pointed version of the Danaë myth in which an insouciant dictator (of whom it is hard not to think: Putin) sits on a high beam on a saddle, shelling nuts all day while gold coins rain down from a vast shower-head only to be hoisted in buckets by faceless thuggish men in suits.
(10) Serious septal injuries may include comminuted caudal border fractures, septal crushes, and saddling with loss of septal height.
(11) For the saddle coil, signal-to-noise per pixel was superior to the head coil for depths below 8.5 cm for magnifications up to 30%.
(12) But they also saddled governments with large deficits, which soon came to be viewed as an obstacle to recovery – the opposite of what Keynes taught.
(13) Correction of the saddle nasal deformity requires generous elevation and mobilization of the overlying soft tissue, the restoration of skeletal support, and the provision of nasal mucosa lining ("the forgotten link").
(14) The patient showed characteristic features: upper and lower eyelids connected to each other by a string-like epithelium, low hairline, epicanthal folds, saddle nose with a broad, flat root, micrognathia, short neck, high-arched palate, prominent xiphisternum, wide-spaced nipples, bilateral pes equinovarus, fifth toes that overlapped the fourth toes bilaterally, a deep fissure between the first and second toes bilaterally, and abnormal flexions of fingers and toes.
(15) Murdoch’s humblest day didn’t last long, with Rebekah Brooks back in the saddle an James Murdoch back in charge of Sky and angling to take over the whole company.
(16) High-resolution magnetic resonance (MR) images of the skin were acquired with a whole-body MR system at 1.5 T by adding a specific imaging module: A saddle-shaped surface gradient coil was connected in place of one of the gradient coils of the system, and a surface radio-frequency coil with a 1.5-cm radius was placed at the center of the gradient coil.
(17) Other clinical manifestations were saddle nose (3 cases), painful swelling of ear (2 cases), arthralgia (1 case) ophthalmodynia (1 case).
(18) While traditional causes of occlusion (saddle embolus and thrombosis) are the most frequent, vasculitis and hypercoagulable states have recently been suggested as etiologies.
(19) The equipment consisted of a sound transducer applied to the skin adjacent to the trachea and a radio transmitter attached to the saddle.
(20) Successively: correction of the dorsum (resection of the bony hump) with incorrect nasofrontal angle, residual hump, "saddle nose"; lateral osteotomy and bony step; transversal and paramedian osteotomy with possibility of "open roof" so as residual deviation.