(n.) That which is borne with labor or difficulty; that which is grievous, wearisome, or oppressive.
(n.) The capacity of a vessel, or the weight of cargo that she will carry; as, a ship of a hundred tons burden.
(n.) The tops or heads of stream-work which lie over the stream of tin.
(n.) The proportion of ore and flux to fuel, in the charge of a blast furnace.
(n.) A fixed quantity of certain commodities; as, a burden of gad steel, 120 pounds.
(n.) A birth.
(v. t.) To encumber with weight (literal or figurative); to lay a heavy load upon; to load.
(v. t.) To oppress with anything grievous or trying; to overload; as, to burden a nation with taxes.
(v. t.) To impose, as a load or burden; to lay or place as a burden (something heavy or objectionable).
(n.) The verse repeated in a song, or the return of the theme at the end of each stanza; the chorus; refrain. Hence: That which is often repeated or which is dwelt upon; the main topic; as, the burden of a prayer.
(n.) The drone of a bagpipe.
(n.) A club.
Example Sentences:
(1) Senator Bernie Sanders of Vermont, who is also seeking the Democratic presidential nomination, recently proposed a bill that would ease the financial burden of prescription drugs on elderly Americans by allowing Medicare, the national social health insurance program, to negotiate with the pharmaceutical companies to keep prices down.
(2) Finally, before the advent of the third-party payment, operations were avoided because of the financial burden.
(3) However, civil society groups have raised concerns about the ethics of providing ‘climate loans’ which increase the country’s debt burden.
(4) The parasites were highly aggregated within the study community, with most people harbouring low burdens while a few individuals harboured very heavy burdens.
(5) Economic burdens for postmarketing research should be shared jointly by the research-oriented and generic drug companies.
(6) There is general agreement that suicides are likely to be undercounted, both for structural reasons (the burden-of-proof issue, the requirement that the coroner or medical examiner suspect the possibility of suicide) and for sociocultural reasons.
(7) The art Kennard produced formed the basis of his career, as he recounted later: “I studied as a painter, but after the events of 1968 I began to look for a form of expression that could bring art and politics together to a wider audience … I found that photography wasn’t as burdened with similar art historical associations.” The result was his STOP montage series.
(8) The analysis indicated a high cost burden for families in all disease categories studied, although a lack of uniformity in data presentation and in the variables studied prevented specific generalizations to be made about the numbers or characteristics of families with high costs.
(9) "Public servants did nothing to cause the slump but are being asked to bear an unfair share of the burden.
(10) The irony of this type of self-manipulation is that ultimately the child, or adult, finds himself again burdened by impotence, though it is the impotence of guilt rather than that of shame.
(11) The aim of the study was to find whether treatment would result in an improvement of cognition, of functioning in daily life, decrease of behavioural disturbances, and decrease in burden experienced by the carers.
(12) Lymph proliferative disorders with a high mitotic rate, and large tumor burden, regardless of histologic features, should be treated prophylactically against tumor lysis if regrowth between cycles occurs.
(13) These data indicate that, compared with animals at sea level, animals at altitude have an increased body burden of COHb and will attain the COHb level associated with the National Ambient Air Quality Standard for CO more quickly when breathing CO.
(14) Macro-epidemiology is concerned with the absolute and relative contributions of particular causes or diseases to the overall burden of ill-health in a population.
(15) Communicable diseases represent a considerable burden in terms of suffering and costs.
(16) This is indirect evidence suggesting that mercury from dental amalgam fillings may contribute to the body burden of mercury in the brain.
(17) The gender-specific kinship relationship of patients and their care providers has not generally been investigated in studies of caregiver burden and well-being.
(18) In predicting response to therapy, poor prognostic factors included large tumor burdens, advanced disease stage, and chemotherapy-resistant tumors.
(19) Radical postoperative irradiation (A) is burdened by 3 serious complications and a considerably higher amount of complaints.
(20) MMC and 5-FU did not show significant activity against large tumor burden, while a relatively good activity was detected in patients with minimal disease.
Strain
Definition:
(n.) Race; stock; generation; descent; family.
(n.) Hereditary character, quality, or disposition.
(n.) Rank; a sort.
(a.) To draw with force; to extend with great effort; to stretch; as, to strain a rope; to strain the shrouds of a ship; to strain the cords of a musical instrument.
(a.) To act upon, in any way, so as to cause change of form or volume, as forces on a beam to bend it.
(a.) To exert to the utmost; to ply vigorously.
(a.) To stretch beyond its proper limit; to do violence to, in the matter of intent or meaning; as, to strain the law in order to convict an accused person.
(a.) To injure by drawing, stretching, or the exertion of force; as, the gale strained the timbers of the ship.
(a.) To injure in the muscles or joints by causing to make too strong an effort; to harm by overexertion; to sprain; as, to strain a horse by overloading; to strain the wrist; to strain a muscle.
(a.) To squeeze; to press closely.
(a.) To make uneasy or unnatural; to produce with apparent effort; to force; to constrain.
(a.) To urge with importunity; to press; as, to strain a petition or invitation.
(a.) To press, or cause to pass, through a strainer, as through a screen, a cloth, or some porous substance; to purify, or separate from extraneous or solid matter, by filtration; to filter; as, to strain milk through cloth.
(v. i.) To make violent efforts.
(v. i.) To percolate; to be filtered; as, water straining through a sandy soil.
(n.) The act of straining, or the state of being strained.
(n.) A violent effort; an excessive and hurtful exertion or tension, as of the muscles; as, he lifted the weight with a strain; the strain upon a ship's rigging in a gale; also, the hurt or injury resulting; a sprain.
(n.) A change of form or dimensions of a solid or liquid mass, produced by a stress.
(n.) A portion of music divided off by a double bar; a complete musical period or sentence; a movement, or any rounded subdivision of a movement.
(n.) Any sustained note or movement; a song; a distinct portion of an ode or other poem; also, the pervading note, or burden, of a song, poem, oration, book, etc.; theme; motive; manner; style; also, a course of action or conduct; as, he spoke in a noble strain; there was a strain of woe in his story; a strain of trickery appears in his career.
(1) These variants may serve as useful gene markers in alcohol research involving animal model studies with inbred strains in mice.
(2) None of the strains was found to be positive for cytotoxic enterotoxin in the GM1-ELISA.
(3) They are going to all destinations.” Supplies are running thin and aftershocks have strained nerves in the city.
(4) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(5) We were able to detect genetic recombination between vaccine strains of PRV following in vitro or in vivo coinoculation of 2 strains of PRV.
(6) All of the strains examined were motile and hemolytic and produced lipase and liquid gelatin.
(7) The taxonomic relationship of strains H4-14 and 25a with previously described Xanthobacter strains was studied by numerical classification.
(8) Whereas strain Ga-1 was practically avirulent for mice, strain KL-1 produced death by 21 days in 50% of the mice inoculated.
(9) These results suggest that the pelvic floor is affected by progressive denervation but descent during straining tends to decrease with advancing age.
(10) We also show that the gene of the main capsid protein is expressed from its own promoter in an Escherichia coli strain.
(11) Sequence variation in the gp116 component of cytomegalovirus envelope glycoprotein B was examined in 11 clinical strains and compared with variation in gp55.
(12) By hybridization studies, three plasmids in two forms (open circular and supercoiled) were detected in the strain A24.
(13) In addition, the fact that microheterogeneity may occur without limit in the mannans of the strains suggests that antibodies with unlimited diverse specificities are produced directed against these antigenic varieties as well.
(14) Strains isolated from the environment and staff were not implicated.
(15) The compressive strength of bone is proportional to the square of the apparent density and to the strain rate raised to the 0.06 power.
(16) Escherichia enterotoxigenic strains, Yersinia enterocolitica and Salmonella typhimurium virulent strains, Campylobacter jejuni clinical isolates possess more pronounced capacity for adhesion to enteric cells of Peyer's plaques than to other types of epithelial cells, which may be of importance in the pathogenesis of these infections.
(17) These sequences are also conserved in the same arrangement in minor sequence classes of minicircles from this strain.
(18) The isoelectric points (pI) of E1 and E2 for all VEE strains studied were approx.
(19) One rat strain (TAS) is susceptible to the anticoagulant and lethal effects of warfarin and the other two strains are homozygous for warfarin resistance genes from either wild Welsh (HW) or Scottish (HS) rats.
(20) In these bitches, a strain of E coli identical to the strain in the infected uterus was isolated.