(1) The nucleotide sequence of genome segment A cDNA of the STC strain of infectious bursal disease virus (IBDV) was determined and compared with sequences of the homologous genome segment of the 002-73 strain of IBDV and the Jasper strain of infectious pancreatic necrosis virus (IPNV).
(2) Histopathologically, infectious bursal disease was characterized by bursal and thymic necrosis, aplastic anemia, acute hepatitis with fatty change, and systemic inflammatory response.
(3) Bursas from some of these chicks were examined for infectious bursal agent-specific fluorescence four days after vaccination and bursas from others were examined for histological lesions of infectious bursal disease 21 days after vaccination.
(4) Most colonisation of bursal follicles probably occurs prior to day 13.
(5) Using neutralizing monoclonal antibodies, three categories of escape mutants were selected from a stock of wild-type infectious bursal disease virus (IBDV).
(6) Consistent with persistent embryonic viral infection and altered bursal function, only IgM-producing cells were detected in the spleens of 7-day-old experimental birds.
(7) Direct injection of antigen into bursal tissue of young chickens followed by subsequent intravenous immunization markedly stimulated agglutinin production against Brucella abortus.
(8) Coccidial life-cytle stages were detected in the bursa of Fabricius of broiler chickens inoculated with Eimeria tenella, whether or not the chickens had previously been infected with infectious bursal disease virus (IBDV).
(9) Infectious bursal disease virus alone induced a persistent depression of Ia-expressing cells in the bursa and the spleen and no measurable change in the bone marrow lymphocyte subpopulations.
(10) The antigen-specific recovery was observed by simultaneous administration of sterile antigens into the bursal lumen at the time of BDL.
(11) Diversification within these tumor cells seems to occur by gene conversion events comparable with those observed in bursal B cells.
(12) Essential bursal microenvironmental elements, however, are altered or lost following TP treatment, while bursae from Cy-injected birds can be reconstituted with donor precursors.
(13) It was concluded that virus susceptibility is most likely determined at the bursal stem cell level of differentiation, possibly by a process of allelic exclusion at the retroviral receptor locus.
(14) Two independent non-overlapping epitopes could be demonstrated on the structural protein VP3 of infectious bursal disease virus by non-neutralizing monoclonal antibodies produced against serotypes I and II.
(15) When injected subcutaneously it does not reduce bursal weight and the histological pattern does not change, while primary and secondary immune responses are significantly lowered.
(16) Quails developed necrotizing tracheitis, proliferative and necrotizing bronchitis and pneumonia; multifocal necrotizing hepatitis; necrotizing splenitis, with or without hyperplasia of splenic mononuclear phagocytes; bursal lymphoid necrosis; and bursal atrophy.
(17) Maturation of bursal stem cells in an allogeneic environment was studied.
(18) Specific antibodies were investigated in serums of chicks vaccinated with live vaccine and revaccinated with inactivated vaccine against the infectious bursal disease virus, using three methods.
(19) The developmental and phenotypic characteristics of the bursal lymphocytes and chicken B cell lines that express RAG-2 mRNA demonstrate that selective RAG-2 expression occurs specifically in B cells undergoing Ig diversification by gene conversion.
(20) From these conclusions the etiology of the dysgammaglobulinemia in UM-B19 chickens is hypothesized to be primarily due to delayed bursal development: Immature BG cells are eliminated by environmental antigens during the neonatal period in a process similar to tolerance induction.
Bursar
Definition:
(n.) A treasurer, or cash keeper; a purser; as, the bursar of a college, or of a monastery.
(n.) A student to whom a stipend or bursary is paid for his complete or partial support.
Example Sentences:
(1) The bursar could not have known that Valemont’s activities had come under scrutiny from an inquiry probing an audacious international money-laundering scheme .
(2) There was nothing here to trouble the school bursar, who did nothing wrong.
(3) His father, the Rev Harry Carpenter, was Warden of Keble College, and Humphrey recalled as a small boy roaming the gothic vastness of the lodgings and college on his tricycle, terrorising the undergraduates and bursar in what he described as "a wonderful Gormenghast existence".
(4) Payne says she has had no guidance in how to apply for available money either, and the bursar, Elizabeth Harrex, confirms that there has been no communication from the local authority.
(5) A fastidiously shoe-shone testament to the lament that modern British politics doesn't attract the best and the brightest, Duncan Smith would, in a true meritocracy, have come out of a distinctly average stint in the army and taken a position as a bursar of some minor public school clinging desperately to the Sussex cliffs.
(6) Brinton, a former Cambridge university bursar, who has moved to Watford, dismisses Harrington as a well-heeled novice ("his literature is hopeless"), a latecomer and – for Muslim voters – executive board chairman of Conservative Friends of Israel.
(7) This, says the school's bursar, Dawn Revess, will be “the real community hub, the equivalent of the local village hall.” So far it has hosted a talk by the Met Police commissioner and a couple of commercial conferences.
(8) He had led a fairly active life and recently retired (1986) as a bursar from a secondary school.