(n.) A turning or sliding piece which, by the shape of its periphery or face, or a groove in its surface, imparts variable or intermittent motion to, or receives such motion from, a rod, lever, or block brought into sliding or rolling contact with it.
(n.) A curved wedge, movable about an axis, used for forcing or clamping two pieces together.
(n.) A projecting part of a wheel or other moving piece so shaped as to give alternate or variable motion to another piece against which it acts.
(n.) A ridge or mound of earth.
(a.) Crooked.
Example Sentences:
(1) The combined results suggest that any possible heterogeneity in the L-CAM genes is not reflected in the size of either the mRNA or protein.
(2) The chick chorioallantoic membrane (CAM) model was used to study vascular effects of photodynamic therapy (PDT) and hyperthermia (HPT) and the synergism of these modalities.
(3) These studies indicate that at each site of induction during feather morphogenesis, a general pattern is repeated in which an epithelial structure linked by L-CAM is confronted with periodically propagating condensations of cells linked by N-CAM.
(4) By 3 d in the chick embryo, the first neurons detected by antibodies to Ng-CAM are located in the ventral neural tube; these precursors of motor neurons emit well-stained fibers to the periphery.
(5) CD-349 inhibited the [3H]CD-349 binding to CaM, at a concentration producing a 50% inhibition (IC50) of 2.4 microM, whereas the CaM antagonist, trifluoperazine hydrochloride (TFP), stimulated the [3H]CD-349 binding to CaM.
(6) Comparison of the native and derivatized wheat germ CaMs with native bovine testis CaM indicates that the concentrations of these proteins required for half-maximal stimulation of either erythrocyte membrane Ca2+-ATPase activity or cardiac sarcoplasmic reticulum phosphorylation are very similar.
(7) CAM, especially CD11c, were also detected in cytoplasmic granules by immunostaining in IL2-activated NK cells.
(8) compounds tested, chlordecone is a specific inhibitor of CaM-activated PDE.
(9) In situ hybridization in normal visual cortex revealed a complex sublaminar organization of GAD-expressing cells within layers IVC and VI and a distribution of CaM II kinase alpha-expressing cells that was greatest in layers II, III, IVB, and VI.
(10) We are describing two post-translational modifications; glycosylation and glypiation; which affect the neural cell adhesive molecule (N-CAM).
(11) These results show that mitogenic activation of human fibroblasts leads to the binding of Ca2+ to CaM and the subsequent activation of CaM-dependent processes.
(12) Conversion of S180 cells to a communication-competent phenotype by transfection with a cDNA encoding the cell-cell adhesion molecule L-CAM induced phosphorylation of connexin43 to the P2 form; conversely, blocking junctional communication in ordinarily communication-competent cells inhibited connexin43-P2 formation.
(13) The responsiveness of test tissue to low versus high androgen levels was evaluated in this CAM assay using both cellular morphology and mitotic index as response criteria.
(14) Immunoblot together with immunoprecipitation experiments with cell lines or tissue extracts showed that N-CAM are the major glycoproteins bearing such polysialosyl units.
(15) The fluorescent dihydropyridine calcium antagonist drug felodipine binds to calmodulin (CaM) in a Ca2+-dependent manner.
(16) However, whereas a critical value of N-CAM expression is required for increased neurite outgrowth, with small increases above this value having substantial effects, N-cadherin promotes neurite outgrowth in a highly linear manner.
(17) These results provide structural and functional evidence that CaM and CDP-I act synergistically in the regulated proteolysis of fodrin.
(18) In this study, we examined the modulation of cell surface expression of MHC antigens and the CAM intercellular adhesion molecule 1 (ICAM-1), lymphocyte function antigen 3 (LFA-3), and CD44 on human dermal microvascular endothelial cells (HDMEC) both grown in monolayers and differentiated into capillary-like structures on the basement membrane-like substrate matrigel.
(19) The second type of protein bound 125I-CaM only when the free Ca2+ concentration was below 1-2 microM and included polypeptides of 95 kDa (E95) and 105 kDa (E105).
(20) Day and night forms of phosphoenolpyruvate carboxylase (EC 4.1.1.31) (PEPC) were extracted from leaves of the CAM plants Kalanchoe daigremontiana, K. tubiflora and K. blossfeldiana previously fed with [32P] labelled phosphate solution.
Mam
Definition:
(n.) Mamma.
Example Sentences:
(1) PFP-MAM is separated by capillary GC and identified mass spectrometrically by selected ion monitoring (SIM).
(2) In this study the morphology of the lateral geniculate nucleus and occipital cortex in rats with methylazoxymethanol acetate (MAM Ac)-induced micrencephaly was examined.
(3) The use of monoclonal antibodies and alpha MAM-6 indicated that the majority of TEC were of medullary origin.
(4) The results suggest that rats exposed to MAM in varying doses would be useful for evaluating the developmental process of neurons and its unification.
(5) Also analogues seem to be the producing of the so-called instinctives as mam(m)a and papa by somewhat older babies which are able to pass over from the babbling into permanent words of the adults' speech in which they persist if used without shifting of sounds since they are produced de novo generation by generation, but they are subordinate to shifting and possible extinction if used in the form of derivatives in the standard language, and some phenomena of the phylogenesis as the survival of less differentiated species contrary to the relatively quick extinction of the highly specialized ones.
(6) Liver microsomes isolated from rats fed the 3 diets metabolized MAM to formic acid and methanol in vitro, but liver microsomes from rats fed the continuous ethanol diet were 12 to 15 times more active than liver microsomes from rats fed the control diet.
(7) Too proud to ask for help, the alarm bells rang in the week before his death when he accepted a tenner from his mam.
(8) A quantitative sandwich radioimmunoassay, using 115D8 as catcher and as tracer antibody, has been developed to detect MAM-6 in serum.
(9) To further analyze the apparent colocalization of ricin and MAM-6 in the perinuclear Golgi region, immunogold cytochemistry on ultracryosections was performed.
(10) The brain weights in the MNU- and MAM-treated pups on postnatal day 22 were significantly less than those in the control pups.
(11) MAM-6 might be considered as a marker of severe (premalignant) dysplasia in adenomas of the large intestine.
(12) Microradiographical and histological investigations showed that the cranial base lordosis was more pronounced in the MAM rats than in the controls, and that the width of the spheno-occipital synchondrosis was reduced mainly due to reduction in the central zone.
(13) These results suggest that working memory disorders of MAM rats on radial maze tasks may be due to the lowering of cholinergic functions in their hippocampus and cerebral cortex.
(14) Cumulative properties indicate that MAM is the guinea pig analogue of human Mo1 and mouse Mac-1.
(15) The controls of a fibroblastic cell culture derived from gill tissue of bluegill sunfish showed spontaneous transformation after 6 months of passage, similar to the transformation observed in the experimental MAM acetate treated gill cultures.
(16) One of the antigens, MAM-6, appeared to be an important epithelial marker, present in all normal and neoplastic breast tissue samples, in about 80% of non-mammary normal tissues and in more than 90% of non-mammary epithelial tumours.
(17) Pretreatment with CCl4 caused not only early death from chemical toxicity of MAM but also an increase in small-bowel tumors.
(18) Unlike paramagnetic material, MAM appears effective as a small-bowel contrast material.
(19) 5HT-immunoreactive neurons in the MAM-rats were reduced in number and irregularly distributed in the dorsal and median raphe nuclei compared with those in the control.
(20) Treatment with MAM, 3 to 6 hr after Con A addition, partially blocks the enhancement.