(n.) A turning or sliding piece which, by the shape of its periphery or face, or a groove in its surface, imparts variable or intermittent motion to, or receives such motion from, a rod, lever, or block brought into sliding or rolling contact with it.
(n.) A curved wedge, movable about an axis, used for forcing or clamping two pieces together.
(n.) A projecting part of a wheel or other moving piece so shaped as to give alternate or variable motion to another piece against which it acts.
(n.) A ridge or mound of earth.
(a.) Crooked.
Example Sentences:
(1) The combined results suggest that any possible heterogeneity in the L-CAM genes is not reflected in the size of either the mRNA or protein.
(2) The chick chorioallantoic membrane (CAM) model was used to study vascular effects of photodynamic therapy (PDT) and hyperthermia (HPT) and the synergism of these modalities.
(3) These studies indicate that at each site of induction during feather morphogenesis, a general pattern is repeated in which an epithelial structure linked by L-CAM is confronted with periodically propagating condensations of cells linked by N-CAM.
(4) By 3 d in the chick embryo, the first neurons detected by antibodies to Ng-CAM are located in the ventral neural tube; these precursors of motor neurons emit well-stained fibers to the periphery.
(5) CD-349 inhibited the [3H]CD-349 binding to CaM, at a concentration producing a 50% inhibition (IC50) of 2.4 microM, whereas the CaM antagonist, trifluoperazine hydrochloride (TFP), stimulated the [3H]CD-349 binding to CaM.
(6) Comparison of the native and derivatized wheat germ CaMs with native bovine testis CaM indicates that the concentrations of these proteins required for half-maximal stimulation of either erythrocyte membrane Ca2+-ATPase activity or cardiac sarcoplasmic reticulum phosphorylation are very similar.
(7) CAM, especially CD11c, were also detected in cytoplasmic granules by immunostaining in IL2-activated NK cells.
(8) compounds tested, chlordecone is a specific inhibitor of CaM-activated PDE.
(9) In situ hybridization in normal visual cortex revealed a complex sublaminar organization of GAD-expressing cells within layers IVC and VI and a distribution of CaM II kinase alpha-expressing cells that was greatest in layers II, III, IVB, and VI.
(10) We are describing two post-translational modifications; glycosylation and glypiation; which affect the neural cell adhesive molecule (N-CAM).
(11) These results show that mitogenic activation of human fibroblasts leads to the binding of Ca2+ to CaM and the subsequent activation of CaM-dependent processes.
(12) Conversion of S180 cells to a communication-competent phenotype by transfection with a cDNA encoding the cell-cell adhesion molecule L-CAM induced phosphorylation of connexin43 to the P2 form; conversely, blocking junctional communication in ordinarily communication-competent cells inhibited connexin43-P2 formation.
(13) The responsiveness of test tissue to low versus high androgen levels was evaluated in this CAM assay using both cellular morphology and mitotic index as response criteria.
(14) Immunoblot together with immunoprecipitation experiments with cell lines or tissue extracts showed that N-CAM are the major glycoproteins bearing such polysialosyl units.
(15) The fluorescent dihydropyridine calcium antagonist drug felodipine binds to calmodulin (CaM) in a Ca2+-dependent manner.
(16) However, whereas a critical value of N-CAM expression is required for increased neurite outgrowth, with small increases above this value having substantial effects, N-cadherin promotes neurite outgrowth in a highly linear manner.
(17) These results provide structural and functional evidence that CaM and CDP-I act synergistically in the regulated proteolysis of fodrin.
(18) In this study, we examined the modulation of cell surface expression of MHC antigens and the CAM intercellular adhesion molecule 1 (ICAM-1), lymphocyte function antigen 3 (LFA-3), and CD44 on human dermal microvascular endothelial cells (HDMEC) both grown in monolayers and differentiated into capillary-like structures on the basement membrane-like substrate matrigel.
(19) The second type of protein bound 125I-CaM only when the free Ca2+ concentration was below 1-2 microM and included polypeptides of 95 kDa (E95) and 105 kDa (E105).
(20) Day and night forms of phosphoenolpyruvate carboxylase (EC 4.1.1.31) (PEPC) were extracted from leaves of the CAM plants Kalanchoe daigremontiana, K. tubiflora and K. blossfeldiana previously fed with [32P] labelled phosphate solution.
Toe
Definition:
(n.) One of the terminal members, or digits, of the foot of a man or an animal.
(n.) The fore part of the hoof or foot of an animal.
(n.) Anything, or any part, corresponding to the toe of the foot; as, the toe of a boot; the toe of a skate.
(n.) The journal, or pivot, at the lower end of a revolving shaft or spindle, which rests in a step.
(n.) A lateral projection at one end, or between the ends, of a piece, as a rod or bolt, by means of which it is moved.
(n.) A projection from the periphery of a revolving piece, acting as a cam to lift another piece.
(v. t.) To touch or reach with the toes; to come fully up to; as, to toe the mark.
(v. i.) To hold or carry the toes (in a certain way).
Example Sentences:
(1) Five cases of mycetoma of bone involving patella, shaft of tibia, medial malleolus, calcaneum and phalanx of great toe are presented.
(2) Doctors, who once treated human body as an entity, are so specialized that none seems to know any more that the head bone is still indirectly connected to the great toe.
(3) "The new feminine ideal is of egg-smooth perfection from hairline to toes," she writes, describing the exquisite agony of having her fingers, arms, back, buttocks and nostrils waxed.
(4) The present study includes six patients, (involving ten feet), who developed hallux varus and great toe clawing after McBride procedures were performed by various orthopedic surgeons.
(5) Impairments of hearing, of mobility, of cutting toe-nails and of general physical activity were the conditions which were most frequently named.
(6) Despite the 2 operations and extensive medical treatment with vasodilators, anticoagulants, and other medication, the pain and limp persisted and a cutaneous necrosis of the 1st and 5th left toes was observed.
(7) We present our results with 8 free transfers of the toe pulp and demonstrate the successful restoration of a well-padded and sensitive fingertip.
(8) Finally, secondary reconstruction techniques are presented, always compared with classical techniques (free 2nd toe transfer versus pollicization).
(9) An equal increase in the number of eroded joints in hands and toes was seen in the penicillamine and the gold group.
(10) Economic analyses were also adjusted for hatchery toe-clipping costs.
(11) The core temperature is taken from the rectum, the nasopharynx or tympanic membrane, and the peripheral temperature from the great toe.
(12) As Cavani was shunted of the ball, it broke to Suarez, who aimed a quick-witted toe-poke at the bottom corner from 15 yards, only to be denied by Buffon, who showed tremendous agility to plunge to his right and tip it around the post!
(13) Computer digitization revealed that distal anastomotic intimal hyperplasia occurred exclusively at the heel and the toe of the graft and the floor of the host artery.
(14) These tests include measurement of the ankle-brachial systolic pressure ratio, a treadmill exercise test, a reactive hyperaemia test, and assessment of toe-pulse reappearance time.
(15) In analogy to tip-toeing movements, it is concluded that the coactivation pattern is typical for stance conditions with a restricted area of support in order to reduce body sway.
(16) The forms of lutein in the toe web were diester (66%0, free alcohol (26%), and monoester (8%) and their sensitivity to aflatoxin followed the same order.
(17) Therefore, the plantar forces acting under the metatarsal heads of the 1st, 2nd and 5th rays and under the pads of the 1st and 2nd toes were measured during walking, so that with the aid of anthropometric information pertaining to the forefoot, reaction forces in the flexor tendons and in the joints could be estimated.
(18) On other days, she dresses head to toe in bright pink.
(19) Both lower limbs were abnormal: the left had a single slender long bone articulating with the foot, which was markedly dorsiflexed and had only 2 toes; on the right the femur was angulated, the fibula was absent, and only 4 metatarsals were present with 4 toes.
(20) The time course of the ionic outflow from the toe web was determined by conductance measurements in the fluid surrounding the web and compared with the visually observed phenomena.