(n.) A genus of decapod Crustacea, including some of the most common shore crabs of Europe and North America, as the rock crab, Jonah crab, etc. See Crab.
(n.) The fourth of the twelve signs of the zodiac. The first point is the northern limit of the sun's course in summer; hence, the sign of the summer solstice. See Tropic.
(n.) A northern constellation between Gemini and Leo.
(n.) Formerly, any malignant growth, esp. one attended with great pain and ulceration, with cachexia and progressive emaciation. It was so called, perhaps, from the great veins which surround it, compared by the ancients to the claws of a crab. The term is now restricted to such a growth made up of aggregations of epithelial cells, either without support or embedded in the meshes of a trabecular framework.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
(3) Melanoma is the second most common cancer, after testicular cancer, in males in the U.S. Navy.
(4) An application is made to the validity of cancer risk items included in a cancer registry.
(5) This effect was more marked in breast cancer patients which may explain our earlier finding that women with upper body fat localization are at increased risk for developing breast cancer.
(6) In addition, KM231 could detect a small amount of the antigen ganglioside in human gastric normal and cancerous mucosa and in gastric cancer cell lines by HPTLC-immunostaining.
(7) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(8) The inhibitory effects were stronger in A549 lung cancer cells than in HEL cells at the same TFP dose.
(9) The diagnosis of anaplastic thyroid cancer, though suspected, was deferred for permanent sections in all cases.
(10) Thus, our study confirmed that male subjects with a history of testicular maldescent have an increased risk for testis cancer, although the magnitude of this risk was lower than suggested previously.
(11) Flow cytometric DNA analysis was performed on both fresh and on paraffin embedded samples obtained by gastroscopic biopsies in 5 patients with histologically normal gastric mucosa (20 specimens) and by radical gastrectomies in 9 cases of human gastric cancer (36 specimens).
(12) Cop rats, however, possess a single 'suppressor' gene which confers complete resistance to mammary cancer.
(13) No evidence of BPH was observed in 68.4% of patients who had died of cancer.
(14) Since interferon alfa-2b (Intron A) is useful as a single agent, it is important to determine if interferon can be combined with standard chemotherapy to improve both response and survival in patients with cancer.
(15) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(16) Immunohistochemical observation of myoepithelial cells with monoclonal antibody from human mammalian cancer suggested that these cells play an important role in the process of glandular ducts formation.
(17) Providers used the tests significantly more often to evaluate patients with cancer risk factors or for new patients.
(18) Cancer of the mouth, pharynx and esophagus has decreased in all Japanese migrants, but the decrease is much greater among Okinawan migrants, suggesting they have escaped exposure to risk factors peculiar to the Okinawan environment.
(19) In all, 207 cases of liver cancer were seen during this period, giving an incidence of rupture of 14.5%.
(20) Nine of the 12 long-term survivors showed lymph node metastasis and six of the 12 revealed cancer cells at the surgical margins.
Malignancy
Definition:
(n.) The state or quality of being malignant; extreme malevolence; bitter enmity; malice; as, malignancy of heart.
(n.) Unfavorableness; evil nature.
(n.) Virulence; tendency to a fatal issue; as, the malignancy of an ulcer or of a fever.
(n.) The state of being a malignant.
Example Sentences:
(1) In contrast to previous reports, these tumours were more malignant than osteosarcomas and showed a five-year survival rate of only 4-2 per cent.
(2) Oral administration in domestic cats causes malignant hepatomas and tumors of the esophagus and kidney.
(3) In view of reports of the reduction of telomeric repeats in human malignant tumors, we measured the lengths of telomeric repeats in 55 primary neuroblastomas.
(4) The frequency of gastric malignancies in the families of the women with gastric polyps was higher than in the controls and in men, 6.2, 3.1 and 2.4 percent, respectively (p less than 0.05, and p less than 0.025).
(5) In 60 rhesus monkeys with experimental renovascular malignant arterial hypertension (25 one-kidney and 35 two-kidney model animals), we studied the so-called 'hard exudates' or white retinal deposits in detail (by ophthalmoscopy, and stereoscopic color fundus photography and fluorescein fundus angiography, on long-term follow-up).
(6) The only localized tumors known to produce elevation of CEA above the levels observed in non malignant diseases are carcinomas of the large bowel and the pancreas.
(7) Normal cultured human epidermal melanocytes and melanoma cells derived from three different malignant melanomas were examined for synthesis of extracellular matrix components before and after treatment for one day with interferon-gamma, tumor necrosis factor-alpha, or both.
(8) The presence of these markers has facilitated the identification and characterization of the mononuclear cells in a number of animal and human lymphoid malignancies.
(9) Benign and malignant epithelial and soft tissue tumors of the skin were usually negatively stained with MoAb HMSA-2.
(10) HCT were classified by light microscopy as benign (n = 22), intermediate (n = 30), and malignant (n = 13).
(11) This case is unusual in that it demonstrated no malignant epithelium beyond that of a borderline tumor, but met the criteria of malignancy because of its invasiveness and metastasis.
(12) As novel antibody therapeutics are developed for different malignancies and require evaluation with cells previously uncharacterized as antibody-dependent cell-mediated cytotoxicity (ADCC) targets, efficient description of key parameters of the assay system expedites the preclinical assessment.
(13) The fragile site at 10q25 was expressed in larger proportions of malignant than normal cells.
(14) In the control group it was 18% and in other malignancies 20%.
(15) Total lactate dehydrogenase (LDH; EC 1.1.1.27) activity and the percentage distribution of LDH isoenzymes were determined in 127 patients with malignant diseases.
(16) In our opinion, a carcinologically "malignant" metastatic myxoma remains a questionable pathological entity.
(17) Hexokinase, phoshofructokinase, and aldolase appear to be rate-limiting in normal cervix epithelium; however, since the increase in activity of the first two in cancers was least of all the glycolytic enzymes, redundant enzyme synthesis probably occurs in the malignant cell for the enzymes catalysing reversible reactions.
(18) The flow cytometric measured DNA content (i.e., DNA index), S-fractions, and histopathologic malignancy grades were studied for ninety uterine cervical squamous cell carcinomas using tissue biopsies taken prior to radiotherapy.
(19) Changes in the plasma lipid composition are observed in patients and animals with malignancy and certain other diseases that are consistent with peroxidation of plasma lipoprotein lipids.
(20) It was difficult to assess the diagnosis of malignant mesothelioma on isolated differentiated mesothelial cells in pleural fluids or biopsies.