(n.) A genus of decapod Crustacea, including some of the most common shore crabs of Europe and North America, as the rock crab, Jonah crab, etc. See Crab.
(n.) The fourth of the twelve signs of the zodiac. The first point is the northern limit of the sun's course in summer; hence, the sign of the summer solstice. See Tropic.
(n.) A northern constellation between Gemini and Leo.
(n.) Formerly, any malignant growth, esp. one attended with great pain and ulceration, with cachexia and progressive emaciation. It was so called, perhaps, from the great veins which surround it, compared by the ancients to the claws of a crab. The term is now restricted to such a growth made up of aggregations of epithelial cells, either without support or embedded in the meshes of a trabecular framework.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
(3) Melanoma is the second most common cancer, after testicular cancer, in males in the U.S. Navy.
(4) An application is made to the validity of cancer risk items included in a cancer registry.
(5) This effect was more marked in breast cancer patients which may explain our earlier finding that women with upper body fat localization are at increased risk for developing breast cancer.
(6) In addition, KM231 could detect a small amount of the antigen ganglioside in human gastric normal and cancerous mucosa and in gastric cancer cell lines by HPTLC-immunostaining.
(7) In addition to the changes associated with blood group A, we also found a decrease in sugar content, alterations in other antigens, and changes in the levels of several glycosyltransferases in cancerous tissues.
(8) The inhibitory effects were stronger in A549 lung cancer cells than in HEL cells at the same TFP dose.
(9) The diagnosis of anaplastic thyroid cancer, though suspected, was deferred for permanent sections in all cases.
(10) Thus, our study confirmed that male subjects with a history of testicular maldescent have an increased risk for testis cancer, although the magnitude of this risk was lower than suggested previously.
(11) Flow cytometric DNA analysis was performed on both fresh and on paraffin embedded samples obtained by gastroscopic biopsies in 5 patients with histologically normal gastric mucosa (20 specimens) and by radical gastrectomies in 9 cases of human gastric cancer (36 specimens).
(12) Cop rats, however, possess a single 'suppressor' gene which confers complete resistance to mammary cancer.
(13) No evidence of BPH was observed in 68.4% of patients who had died of cancer.
(14) Since interferon alfa-2b (Intron A) is useful as a single agent, it is important to determine if interferon can be combined with standard chemotherapy to improve both response and survival in patients with cancer.
(15) Over the past decade the use of monoclonal antibodies has greatly advanced our knowledge of the biological properties and heterogeneity that exist within human tumours, and in particular in lung cancer.
(16) Immunohistochemical observation of myoepithelial cells with monoclonal antibody from human mammalian cancer suggested that these cells play an important role in the process of glandular ducts formation.
(17) Providers used the tests significantly more often to evaluate patients with cancer risk factors or for new patients.
(18) Cancer of the mouth, pharynx and esophagus has decreased in all Japanese migrants, but the decrease is much greater among Okinawan migrants, suggesting they have escaped exposure to risk factors peculiar to the Okinawan environment.
(19) In all, 207 cases of liver cancer were seen during this period, giving an incidence of rupture of 14.5%.
(20) Nine of the 12 long-term survivors showed lymph node metastasis and six of the 12 revealed cancer cells at the surgical margins.
Proliferation
Definition:
(n.) The continuous development of cells in tissue formation; cell formation.
(n.) The production of numerous zooids by budding, especially when buds arise from other buds in succession.
Example Sentences:
(1) The most actively proliferating region of the excurrent duct system is zone 3 of the epididymis, whereas the least active region is the ductuli efferentes.
(2) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
(3) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(4) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(5) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(6) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(7) Proliferation assays using F3 showed that 15 (14 CD4+ and 1 CD8+) of the 18 isolated clones were specific for T. gondii.
(8) After vascular injury, smooth muscle cells proliferate, reaching a maximum rate at day 2.
(9) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(10) During capillary growth when endothelial cells (EC) undergo extensive proliferation and migration and pericytes are scarce, hyaluronic acid (HA) levels are elevated.
(11) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
(12) T cell costimulation by molecules on the antigen presenting cell (APC) is required for optimal T cell proliferation.
(13) Our prospective study has defined a number of important variables in patients with clinical evidence of mast cell proliferation that can predict both the presence of SMCD and the likelihood of fatal disease.
(14) However, a highly significant upward shift of the proliferating cell compartment was observed in the cancer group, resulting in a specific modification of the [3H]TDR labeling pattern in 6 of 17 specimens.
(15) Anti-5'-NT antibodies had no effect on PHA-induced proliferation.
(16) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(17) Extensive proliferation has been shown to accompany the de novo generation of LAK cytotoxicity.
(18) Proliferating cells were abundant and scattered throughout the stratified epithelium before the appearance of villi.
(19) Proliferation of quiescent hematopoietic stem cells, purified by cell sorting and evaluated by spleen colony assay (CFU-S), was investigated by measuring the total cell number and CFU-S content and the DNA histogram at 20 and 48 hours of liquid culture.
(20) Whereas the growth and division of normal cells is carefully regulated to meet the needs of the body, tumor cells proliferate autonomously and continually, eventually interfering with and destroying the functions of normal tissue.