(1) The subunits also differ in regulation as determined by their interactions with a purified type I regulatory subunit, which has an IC50 for CAPL-A1 that is 3.5 times higher than the IC50 for CAPL-A2.
(2) CAPL-A1 and CAPL-A2, two catalytic subunits of Aplysia cAMP-dependent protein kinase, are encoded by mRNAs generated by alternative splicing of transcripts of a gene that contains two mutually exclusive exon cassettes.
(3) CAPL transcripts are present in several classes of identified neurons containing transmitter-sensitive adenylate cyclase, including sensory cells, bag cells, and the left pleural giant cell.
(4) Cacy is shown to be within 8 kb of Capl in the mouse genome.
(5) CAPL-A1 and CAPL-A2 have now been expressed in insect cells and purified to homogeneity.
(6) CAPL-A1 and CAPL-A2 have different substrate specificities.
(7) cDNA probes for the related genes calcyclin (CACY) and a mouse placental protein (18A2, suggested name Capl) enabled us to confirm and refine the in situ hybridization result assigning CACY to chromosome 1q21-25 and to demonstrate that both genes cosegregate with CAGA and CAGB.
(8) Peripheral blood leukocytes from rainbow trout were found to be caple of participating in a mixed leukocyte reaction.
(9) Interestingly, the expression pattern of S100 alpha, CACY, and CAPL in human tissues differs significantly from that in rodent tissues.
(10) They derive from alternatively spliced transcripts of a single gene (CAPL) containing two mutually exclusive exon cassettes.
(11) Whereas CACY and CAPL mRNAs are expressed ubiquitously, S100 alpha mRNA is restricted to heart, skeletal muscle, and brain.
(12) Capl was mapped to a region of chromosome 3 in the mouse using the BXD recombinant inbred strain mice where the p11 protein (calpactin light chain Cal1l), another S100 family member, has been localized.
(13) Transcripts encoding CAPL-B, an apparent member of the cyclic-nucleotide-regulated kinase subfamily in Aplysia californica, are found exclusively in the ovotestis and are concentrated in meiotic and postmeiotic spermatogenic cells.
(14) The CAPL-B polypeptide is present in mature spermatozoa, suggesting that the kinase plays a part in regulating events associated with fertilization.
(15) By PCR technology we identified three members of the S100 protein family (S100 alpha, CACY, and CAPL) in the human heart.
(16) For example, kcat and Km values for the peptide LRRASLG (kemptide) are 42 s-1 and 36 microM and 28 s-1 and 17 microM for CAPL-A1 and CAPL-A2, respectively.
Wire
Definition:
(n.) A thread or slender rod of metal; a metallic substance formed to an even thread by being passed between grooved rollers, or drawn through holes in a plate of steel.
(n.) A telegraph wire or cable; hence, an electric telegraph; as, to send a message by wire.
(v. t.) To bind with wire; to attach with wires; to apply wire to; as, to wire corks in bottling liquors.
(v. t.) To put upon a wire; as, to wire beads.
(v. t.) To snare by means of a wire or wires.
(v. t.) To send (a message) by telegraph.
(v. i.) To pass like a wire; to flow in a wirelike form, or in a tenuous stream.
(v. i.) To send a telegraphic message.
Example Sentences:
(1) They could go out and trade for a pitcher such as the New York Mets’ Bartolo Colón , an obvious choice despite his 41 years, but he would come with an $11m price tag for next season and have to pass through the waiver wires process first – considering the wily mood Billy Beane is in this year, the A’s could be the team that blocks such a move.
(2) The solution to these problems would seem either to reduce the time spent in rectangular wires or to change to a bracket with reduced torque, together with appropriate second order compensations in the archwire or the bracket.
(3) The major difficulty encountered with the current technique is the danger of neurologic injury during the passage and handling of conventional wires, especially in extensive procedures.
(4) I have the BBC app on my phone and it updates me, and I saw the wire ‘Malaysian flight goes missing over Ukraine.’ I’m like, well it’s probably the Russians who shot it down.
(5) For the attachment of adherent cells, microcarriers or wire springs can be applied to increase the internal surface of the bioreactor.
(6) Extraction tools included flexible, telescoping sheaths advanced over the lead to dilate scar tissue and apply countertraction, deflection catheters, and wire basket snares.
(7) It is not same to the stainless steel wire of traditional removable appliances which must be activated every time to produce a little tooth movement.
(8) Whereas in flexion stress all methods showed a sufficient stability, the rotation tests proved, that in case of a dorsal instability of the lower cervical spine, posterior interlaminar wiring or anterior plate stabilization showed no reliable stabilization effect.
(9) Medial canthal tendon resection and tucks or transnasal wiring are then performed.
(10) Overhead wire problems were causing delays on the east coast mainline into London King's Cross.
(11) The steerable guide wire enabled the angioscopic catheter to be accurately and safely inserted into the target lesion in all cases.
(12) The use of wire stylets to facilitate passage of these tubes has increased the chances of unrecognized tracheal intubations, particularly in obtunded patients.
(13) Kirschner improved the wire traction procedure decisevely.
(14) Conservative treatment (immobilisation in a plaster alone) was compared to percutaneous K-wire fixation.
(15) The procedure consists of a Kirschner wire used as the means of traction on the remaining soft tissue of the lower lip, using the upper teeth or pyriform aperture bone as remote fixed points for tissue traction.
(16) Electroencephalographic activity and extracellular discharges from neurons in deep temporal lobe structures were recorded from fine wire microelectrodes chronically implanted in seven psychomotor epileptic patients for diagnostic localization of seizure foci.
(17) Masseter EMG was recorded by fine wire electrodes and amplified by a specially designed amplifier.
(18) Guide-wire fragments retained in the coronary artery system after PTCA are removed either immediately by means of catheter techniques or by urgent operation.
(19) It was smaller than that reported for patients who had received stabilization of the maxilla with intraosseous and maxillomandibular wiring.
(20) At Charity Hospital in New Orleans transverse Kirschner wires have been routinely used to stabilize the zygoma in these cases.