What's the difference between capsaicin and capsicin?
Capsaicin
Definition:
(n.) A colorless crystalline substance extracted from the Capsicum annuum, and giving off vapors of intense acridity.
Example Sentences:
(1) Each subject applied a vehicle cream containing 0.075% capsaicin (Axsain, GalenPharma Inc.) to a 4 cm2 area of skin on one volar forearm and vehicle alone to an identical treatment area on the other forearm, according to a double-blind procedure.
(2) The postnatal development of substance P-like immunoreactivity (SP-LI) in the urinary bladder (assayed by radioimmunoassay and immunohistochemistry) was investigated in rats and compared with changes in the contractile response to acetylcholine, SP or capsaicin.
(3) After pretreatment of pigs with a combination of the H1- and H2-receptor antagonists terfenadine and cimetidine, the vascular and bronchial responses were strongly reduced to both histamine (by greater than 77%) and ascaris (by greater than 58%), but not to capsaicin aerosol.
(4) Capsaicin inhibited the contraction induced by the direct electrical stimulation of the innervated tissues in the presence of tetrodotoxin but not of the surgically denervated tissues.
(5) Sensitivity of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) to capsaicin was investigated in different arterial and venous tissues (mesenteric, renal and femoral artery and vein and carotid artery and jugular vein) of the rat.
(6) The effects of capsaicin (CAP) on membrane properties, action potentials (APs) and outward membrane currents were investigated using the single electrode current and voltage clamp.
(7) The excitatory cardiovascular response to capsaicin in acute spinal rats was markedly reduced by bilateral section of pelvic but not hypogastric nerves.
(8) Animals were killed 12 h after the last injection of saline or OXY, and 72 h after spantide or capsaicin.
(9) The effect of the drugs on respiratory resistance (Rrs), measured using a forced oscillation technique, was measured both before and after the inhalation of a dose of capsaicin which caused less than two coughs.
(10) These effects of capsaicin were resistant to vagotomy.
(11) We review the toxicity of capsaicin and comment briefly on the use of hot peppers in child abuse.
(12) Yet, this difference was based on the impaired noradrenergic counterregulation in capsaicin-pretreated rats, because both groups showed identical responses to captopril following guanethidine-induced adrenergic blockade.
(13) In the present study the long-term effect of topically applied capsaicin on the pain threshold was monitored.
(14) Pretreatment of skin with capsaicin dramatically inhibited the histamine-induced flare response but had no effect on nicotine-induced axon reflex sweating.
(15) Pretreatment of the iris with 20 micrograms of recombinant enkephalinase (neutral endopeptidase; EC 3.4.24.11) totally abolished the contractile response to substance P. Injection of 10 micrograms of capsaicin into the anterior chamber of atropine-treated rabbit eyes in vivo induced an immediate and intense miosis.
(16) In control rats low doses of capsaicin selectively excited mechano-heat sensitive cutaneous nociceptors (polymodal C fiber nociceptors and MH-A delta nociceptors).
(17) The mitochondrial swelling was confirmed to be a specific change produced by capsaicin treatment by the examination of different fixation conditions in both control and capsaicin-treated materials.
(18) In conclusion, ruthenium red selectively inhibits the capsaicin, resiniferatoxin and citric acid-induced excitation of the sensory nerves as revealed by calcitonin gene-related peptide-like immunoreactivity release, bronchoconstriction and coughing, suggesting that these agents share a common mechanism of action.
(19) The "first-phase" is blocked by hexamethonium or atropine and the "second-phase" is eliminated by capsaicin pretreatment.
(20) It is concluded that lowering of the pH induces a Ca2(+)-dependent release of CGRP-LI from capsaicin-sensitive nerves in the guinea-pig urinary bladder.
Capsicin
Definition:
(n.) A red liquid or soft resin extracted from various species of capsicum.
Example Sentences:
(1) The effects of capsaicin on mast cell degranulation in human skin in vivo has been studied by histological examination of skin biopsies after topical capsicin (1%) treatment of stratum corneum-denuded forearm in four volunteers.
(2) The ascending excitatory response is abolished by atropine and hexamethonium and is modulated by capsicin-sensitive fibers.
(3) 'Bronchial' endings were stimulated by both capsicin and phenyl diguanide and were accessible through the bronchial circulation.