(1) "Carnol" insaponificable fraction from "chalky" carnauba wax, was tested for its emulsified system estabilizing abilities.
(2) The phase diagrams of binary mixtures of tripelennamine hydrochloride and tolazoline hydrochloride with carnauba wax and castor wax showed no eutectic formation and gave no indication that a significant interaction was involved.
(3) Pseudoephedrine HCl-carnauba wax microparticles were prepared by a multiple emulsion-melt dispersion technique.
(4) For ternary systems, i.e., drug, carnauba wax, and stearyl alcohol, thermograms of samples prepared by a fusion method differed slightly from those obtained with mixtures formulated by dissolving all ingredients in chloroform and evaporating the solvent.
(5) Microcapsules of salbutamol sulphate were prepared using beeswax and carnauba wax as coating materials.
(6) 5-Fluorouracil:carnauba wax microspheres were prepared using a meltable dispersion process with the aid of a surfactant as a wetting agent.
(7) Although the kinetic results were not indicative of the true release mechanism from a single microsphere, it was believed that 5-fluorouracil release from the microspheres was probably governed by a dissolution process, rather than by a leaching process through the carnauba wax microspheres.
(8) Beeswax alone was not effective but beeswax and carnauba wax combinations were suitable in controlling the in vitro release of the drug.