(n.) A fall of water over a precipice, as in a river or brook; a waterfall less than a cataract.
(v. i.) To fall in a cascade.
(v. i.) To vomit.
Example Sentences:
(1) With fields and fells already saturated after more than four times the average monthly rainfall falling within the first three weeks of December, there was nowhere left to absorb the rainfall which has cascaded from fields into streams and rivers.
(2) The following model is suggested: exogenous ATP interacts with a membrane receptor in the presence of Ca2+, a cascade of events occurs which mobilizes intracellular calcium, thereby increasing the cytosolic free Ca2+ concentration which consequently opens the calcium-activated K+ channels, which then leads to a change in membrane potential.
(3) Each point of the interleukin cascade reaction was examined.
(4) All cellular signals characterized so far are reverted during retrodifferentiation: Redistribution of PKC and down-regulation of c-fos and c-jun contribute to an interruption of the differentiation-associated transsignaling cascade.
(5) Present antihypertensive therapy is directed largely at secondary factors dependent upon or influencing the primary phospholipase C cascade.
(6) Since testosterone influenced both tissue stores and PDBu-stimulated secretion of LHRH and GAP, this steroid may selectively regulate biosynthesis and secretion of pro-LHRH-derived peptides through activation of the metabolic cascade involving the PKC system.
(7) Extracellular signals that promote cell growth activate cascades of protein kinases.
(8) Using serine proteinase inhibitors and antibodies to plasminogen activators as well as a newly described collagenase inhibitor we demonstrate that a protease cascade leads to the activation of an enzyme(s) that cleaves collagen IV.
(9) Low-density lipoprotein (LDL) has a similar hormone-like action and activates the signal transfer cascade that eventually leads to platelet aggregation as well as vascular smooth muscle cell proliferation.
(10) However, the role of calcium homeostasis in regulating several biochemical pathways implicated in other steps of the metastatic cascade suggests that calcium channel antagonists could also inhibit metastasis by other mechanisms.
(11) Since ADH exerts its effects by activation of adenylyl cyclase (AC), further experiments were performed to identify the site at which CP inhibits this cascade.
(12) Autoantibodies which interfere with the function of enzyme cascade systems have also been described in diseases such as acquired haemophilia (anti-factor VIII antibodies) and glomerulonephritis (C3 nephritic factor).
(13) The cyclic adenosine nucleotide pathway is turned off by kinase A activity, whereas the inositol trisphosphate cascade is terminated by kinase C. The data support the concept that desensitization of odorant responses involves phosphorylation of key elements in the transduction cascade.
(14) These hormonal responses trigger a cascade of metabolic adjustments leading to catabolism and substrate mobilization in the postoperative period.
(15) The series filter model is compatible with a simply physical model consisting of cascaded chemical reactions whose forward rate constants are reciprocals of the filter time constants, whose reverse rate constants are negligible, and in which the concentration of an intermediate product controls membrane current.
(16) E capture IC via complement receptors, type 1 (CR1) which can bind to C3b and C4b ligand sites generated on IC during activation of the complement cascade.
(17) The EU was not properly promoting cascade use either he said.
(18) Speculatively, the blockage by dbcAMP of the morphogenetic cascade in the co-cultured system may be related to the inhibition by dbcAMP of testis cord formation in organ cultures of fetal gonads reported by others.
(19) Component of the cascade model represented adventitia and media layers of the wall.
(20) These data suggest that sCR1 inhibits the Arthus reaction by interrupting the activation of the C cascade, hence limiting the detrimental immune complex-induced tissue damage in vivo.
Concatenate
Definition:
(v. t.) To link together; to unite in a series or chain, as things depending on one another.
Example Sentences:
(1) Through concatenation, autocovariance for periodicity identification becomes possible.
(2) Recent data are cited for the proposition that these changes constitute a closed pathogenetic concatenation creating a vicious circle.
(3) The model consists of a concatenation of modules, one for each anatomical section of the periphery.
(4) These studies revealed that biological activity was sensitive to both the identity of the concatenating atoms and the pattern of ring substitution.
(5) Ligation of the blunt end to high molecular weight target DNA proceeds efficiently and there is no tandem concatenation of the adaptor.
(6) Reintroduction of this DNA into mammalian cells as a concatenated phage clone gave rise to dicentric chromosomes which gave rise to a new, stable, chromosome.
(7) Cows with coliform mastitis showed, in addition to fever, tachycardia and ruminal stasis and a concatenation of nonspecific responses, such as neutrophylic leukopenia followed by leukocytosis, lymphopenia, hypocalcaemia, hypoferraemia, hypozincaemia, and hypercupremia, and changes in the concentration of certain serum proteins.
(8) This enhancement of expression can be competed in vivo by concatenated double-stranded oligonucleotides, indicating that protein-DNA binding is a requisite for enhancer activity.
(9) The oscillatory interneurones are connected both intra- and interganglionically to form a topologically complex intersegmental network of concatenated ring circuits that possess the feature of recurrent cyclic inhibition.
(10) The consequential errors led to (a) an injudicious imposition of 'objectivity' at all levels of allocation, (b) an unjustified insistence that the same method be used at each administrative level in an additive and transitive manner, (c) the exclusion of general practitioner services from their considerations, (d) a failure to delineate those decisions which are in fact political decisions, thus to concatenate them, inappropriately, with technical and professional issues.
(11) Furthermore, we observed that concatenated Pit-1 binding sites were able to confer cAMP responsiveness to the thymidine kinase promoter in GC cells.
(12) However, the number of copies of the exogenous DNA sequences retained per average genome in postmetamorphic juveniles was usually less than 0.1 (range 0.05-50), and genome blot hybridizations indicate that these sequences are organized as integrated, randomly oriented, end-to-end molecular concatenates.
(13) It has been shown before (Part I) that covariances or coincidences in the signal activity of a neural net can be used in the construction of a simultaneous functional order in which a modality is represented as a concatenation of districts with a lattice structure.
(14) This finding was seen as consistent with "continuous" correction of movement errors and as contrary to the suggestion that infant movements are concatenations of ballistic movement units whose boundaries are marked by troughs in the speed profile.
(15) A concatenated DNA fragment containing a five-repeat binding site was used for DNase I footprinting.
(16) Thus, the patient's oral reading of a sentence is not a concatenation of isolated words, but depends on an implicit, context-sensitive analysis.
(17) For statistical analysis the night studies of each subject were concatenated.
(18) These include the uptake of the donor DNA by the recipient cells, the transport of the DNA to the nucleus, transient expression prior to integration into the host cell genome, concatenation and integration of the transfected DNA into the host cell genome and finally the stable expression of the integrated genes (2,3).
(19) In contrast, most linearly concatenated DNA molecules (derived from end-to-end joining of microinjected monomeric plasmid DNA) underwent at least two rounds of DNA replication during this same period.
(20) We have constructed an artificial variant of the proenkephalin gene by concatenation of synthetic oligodeoxynucleotides (oligo) coding for Met-enkephalin preceded by two arginines.