(v. t.) To deprive of the testicles; to emasculate; to geld; to alter.
(v. t.) To cut or take out; esp. to remove anything erroneous, or objectionable from, as the obscene parts of a writing; to expurgate.
Example Sentences:
(1) Intact rams exhibited GH secretory episodes of greater (P less than 0.01) amplitude than did castrated lambs.
(2) Positive feedback effects on serum gonadotrophins in castrates were observed following injection of certain doses of some steroids.
(3) In contrast, castration during pseudopregnancy did not abolish the secondary peaks.
(4) No specific labeling could be detected in the adrenocorticotrophs of adrenalectomized rats or gonadotrophs (castration cells) of castrated rats.
(5) In a final experiment, prostatic atrophy in castrate rats was not enhanced by either adrenalectomy or flutamide treatment.
(6) Castrated rams did not show this increase, with or without supplementary testosterone.
(7) Naloxone also prevented testosterone's negative feedback inhibition of serum LH in the castrated male rat.
(8) Moreover, the levels of these parameters were comparable in tumours whether implanted in non-castrated or gonadectomized animals.
(9) Castration of male rats results in a decrease in submandibular gland RSKG-7 mRNA, which can be restored to the normal level by treatment with thyroxine or testosterone.
(10) In vivo administration of anti-EGF antibody or anti-TGF-alpha antibody significantly reduced estrogen-induced labelling index in castrated mouse uterus.
(11) In castrates, the prostatic stroma became thickened, with a large increase in fibrous material between and surrounding each acinus, although smooth muscle cells retained their normal cytology.
(12) Median survival was significantly prolonged in primed animals 191 vs 40 days for untreated animals and 150 days for the nonprimed castration + chemotherapy animals (P less than 0.02).
(13) Adreno-cortical compensation of the concentration of the hormone did not occur in the post-castration period.
(14) Rat dorsal prostate epithelium was studied in intact adult animals, in animals castrated for three days and in rats after inhibition of prolactin secretion.
(15) The ability of melatonin to influence LH pulse frequency in entire and castrated rams indicated that an effect of melatonin on the hypothalamic pulse generator is independent of testicular steroids.
(16) The treatment with supraphysiological doses of the gonadotropin releasing hormone analogue Buserelin results in the suppression of serum testosterone to castration range with a probability of 95% after 28 days.
(17) To determine the effect of photoperiod on substance P, peptide containing neurons were counted in (1) enucleates (n = 6), (2) enucleated castrates treated with testosterone (n = 6), (3) castrates treated with testosterone (n = 4), and (4) intact controls (n = 6).
(18) In addition, there was a marginally significant (P less than 0.1) relationship between prolactin secretion in the castrate ram and the stage of testicular activity in the entire rams with elevated levels associated with regressed activity.
(19) In terms of total cellular receptor content, initial levels were higher in castrate animals, but rapidly fell to intact levels within an hour following estradiol injection.
(20) The effect of naloxone administration on the LH-RH secretion in hypophyseal portal blood and LH secretion in peripheral blood was studied in four short term castrated rams (between 2 to 4 days after castration).
Shorten
Definition:
(a.) To make short or shorter in measure, extent, or time; as, to shorten distance; to shorten a road; to shorten days of calamity.
(a.) To reduce or diminish in amount, quantity, or extent; to lessen; to abridge; to curtail; to contract; as, to shorten work, an allowance of food, etc.
(a.) To make deficient (as to); to deprive; -- with of.
(a.) To make short or friable, as pastry, with butter, lard, pot liquor, or the like.
(v. i.) To become short or shorter; as, the day shortens in northern latitudes from June to December; a metallic rod shortens by cold.
Example Sentences:
(1) The extent of the infectious process was limited, however, because the life span of the cultures was not significantly shortened, the yields of infectious virus per immunofluorescent cell were at all times low, and most infected cells contained only a few well-delineated small masses of antigen, suggestive of an abortive infection.
(2) Hearing loss at 8 kHz would shorten the I-V interval, while a loss at 4 kHz would be expected to lengthen the interval.
(3) Both systems indicated that the Kupffer cell modified endotoxin by enriching the lipid content of the molecule and shortening the length of the O-antigen.
(4) Platelet survival time in patients with Crohn's disease proved to be significantly shortened (p less than 0.001), whereas platelet turnover appeared augmented.
(5) Shorten said any arrangement needed to be consistent with international obligations, with asylum seekers afforded due process and their claims properly assessed.
(6) Rapid, on-site detection of chlamydial antigen in male FVU would shorten the infectious period by hastening diagnosis and treatment.
(7) Isometric exercise induces a significant shortening of both intervals although minor for QT so that the ratio significantly increases in comparison to baseline (p less than .001).
(8) Light-induced cone shortening provides a useful model for stuying nonmuscle contraction because it is linear, slow, and repetitive.
(9) In the V fibers, APD was lengthened by F, Q, and B, and shortened by L and M. The drug-induced changes in the relation between APD and CL were as in the P fibers.
(10) The CL was also longer in the duodenum, whereas the CD was shortened, indicating a reduction of the wave movements from the stomach antrum to the duodenum in the ranitidine periods.
(11) Chloride caused a significant concentration-dependent shortening of myosin rods due to destabilization of the alpha-helical double coiled rod structure.
(12) Strong correlations were found also between postsystolic shortening and thickening measured immediately before reperfusion and systolic shortening and thickening measured after recovery at 2-3 weeks (r = 0.73, n = 28; p less than 0.001 for shortening; r = 0.79, n = 12; p less than 0.01 for thickening).
(13) Slight but significant shortening of the latency of initial positivity in the evoked potential was observed after rearing in the enriched condition as compared to the data obtained from the littermates that were reared in the standard or impoverished conditions.
(14) When using pair stimula, barbamil shortens the period of absolute nonexcitation and the second phase of depression in the cycle of restituted H-reflexes to the second stimula in the pair.
(15) Accordingly, RV systolic SL shortening did not rise despite the substantial augmentation in RV outflow.
(16) Chloroquine administration shortened the time taken to reach peak plasma paracetamol concentration (tmax) in five of the volunteers.
(17) The survival time of the lambs was markedly shortened with the bubble oxygenator, although much longer than had been anticipated.
(18) An algorithm for the treatment of cryptococcosis complicating AIDS may shorten the duration of primary intravenous AB therapy.
(19) VT returned to control levels, expiratory time shortened, and breathing frequency increased.
(20) Isotonically, peak muscle shortening was reduced in the left muscle, whereas time to peak shortening was prolonged in the right myocardium.