(1) Intact rams exhibited GH secretory episodes of greater (P less than 0.01) amplitude than did castrated lambs.
(2) Positive feedback effects on serum gonadotrophins in castrates were observed following injection of certain doses of some steroids.
(3) In contrast, castration during pseudopregnancy did not abolish the secondary peaks.
(4) No specific labeling could be detected in the adrenocorticotrophs of adrenalectomized rats or gonadotrophs (castration cells) of castrated rats.
(5) In a final experiment, prostatic atrophy in castrate rats was not enhanced by either adrenalectomy or flutamide treatment.
(6) Castrated rams did not show this increase, with or without supplementary testosterone.
(7) Naloxone also prevented testosterone's negative feedback inhibition of serum LH in the castrated male rat.
(8) Moreover, the levels of these parameters were comparable in tumours whether implanted in non-castrated or gonadectomized animals.
(9) Castration of male rats results in a decrease in submandibular gland RSKG-7 mRNA, which can be restored to the normal level by treatment with thyroxine or testosterone.
(10) In vivo administration of anti-EGF antibody or anti-TGF-alpha antibody significantly reduced estrogen-induced labelling index in castrated mouse uterus.
(11) In castrates, the prostatic stroma became thickened, with a large increase in fibrous material between and surrounding each acinus, although smooth muscle cells retained their normal cytology.
(12) Median survival was significantly prolonged in primed animals 191 vs 40 days for untreated animals and 150 days for the nonprimed castration + chemotherapy animals (P less than 0.02).
(13) Adreno-cortical compensation of the concentration of the hormone did not occur in the post-castration period.
(14) Rat dorsal prostate epithelium was studied in intact adult animals, in animals castrated for three days and in rats after inhibition of prolactin secretion.
(15) The ability of melatonin to influence LH pulse frequency in entire and castrated rams indicated that an effect of melatonin on the hypothalamic pulse generator is independent of testicular steroids.
(16) The treatment with supraphysiological doses of the gonadotropin releasing hormone analogue Buserelin results in the suppression of serum testosterone to castration range with a probability of 95% after 28 days.
(17) To determine the effect of photoperiod on substance P, peptide containing neurons were counted in (1) enucleates (n = 6), (2) enucleated castrates treated with testosterone (n = 6), (3) castrates treated with testosterone (n = 4), and (4) intact controls (n = 6).
(18) In addition, there was a marginally significant (P less than 0.1) relationship between prolactin secretion in the castrate ram and the stage of testicular activity in the entire rams with elevated levels associated with regressed activity.
(19) In terms of total cellular receptor content, initial levels were higher in castrate animals, but rapidly fell to intact levels within an hour following estradiol injection.
(20) The effect of naloxone administration on the LH-RH secretion in hypophyseal portal blood and LH secretion in peripheral blood was studied in four short term castrated rams (between 2 to 4 days after castration).
Mutilate
Definition:
(a.) Deprived of, or having lost, an important part; mutilated.
(a.) Having finlike appendages or flukes instead of legs, as a cetacean.
(n.) A cetacean, or a sirenian.
(v. t.) To cut off or remove a limb or essential part of; to maim; to cripple; to hack; as, to mutilate the body, a statue, etc.
(v. t.) To destroy or remove a material part of, so as to render imperfect; as, to mutilate the orations of Cicero.
Example Sentences:
(1) Following mass disasters and individual deaths, dentists with special training and experience in forensic odontology are frequently called upon to assist in the identification of badly mutilated or decomposed bodies.
(2) We come to see that some traditions keep us grounded, but that, in our modern world, other traditions set us back.” Female genital mutilation (FGM) affects more than 130 million girls and women around the world.
(3) The central nervous system proximity poses a difficult problem and speaks for an early mutilating surgery.
(4) To avoid mutilating surgery in advanced disease, four courses of VBC chemotherapy were administered prior to resection.
(5) UK Border Force officers have warned of an emerging trend of "cutters" flying into Britain to practise female genital mutilation (FGM).
(6) But she did back moves advocated by the Solicitor-General, Oliver Heald, to place a duty on parents to protect their children and make it illegal to permit their daughters to be mutilated.
(7) With the first prosecutions under way in the UK and Guinea-Bissau , an increased focus on strengthening the law in Kenya , and a rare conviction in Uganda , positive moves are being made in several countries to implement laws that ban female genital mutilation (FGM).
(8) It has been suggested that in some self-mutilating Tourette patients, HGPRT shows a time-related loss of activity at 4 degrees C, and an unusual isoelectrofocusing pattern.
(9) Its most prominent but by no means exclusive feature is self-mutilation.
(10) She explained that, as a baby, she had been subjected to female genital mutilation (FGM): her clitoris cut off and her vagina sealed, with only a small hole remaining for urine and menstruation.
(11) One described the mutilated bodies of three acquaintances – two women and a 14-year-old boy – found in their homes.
(12) Younger children may worry about genital mutilation, and should be reassured.
(13) Allegations that British soldiers murdered insurgents and mutilated their bodies after a fierce firefight in Iraq were roundly rejected by an official inquiry, which also found that a number of prisoners were abused and that troops breached the Geneva convention.
(14) That has left patients with unsatisfactorily functioning vaginas and a mutilated appearance.
(15) As illustrated by a case of dye impression, early extensive surgical exploration and radical removal of the injected agent are mandatory to minimize sequelae and to avoid mutilating complications.
(16) Hence unwilling finger mutilations can scarcely be the result of a "reflex action" of this kind.
(17) The future James I resorted to them on several occasions in Scotland: in 1600, for instance, he had two alleged assassins pickled in whisky, vinegar and allspice, put on trial, and then mutilated.
(18) But Mossad’s toughest opponent was her mother, who started demanding her grand-daughter’s mutilation from when she was just 11 months old.
(19) In one case a laceration over the median nerve was followed by self-induced trauma to the fingers distal to the cut, while the other patient developed self-mutilation in all the extremities following insecticide poisoning and presented with signs of diffuse peripheral neuropathy.
(20) Muslims suspected of collaborating with Djotodia's rebellion have been stoned to death in the streets and their bodies mutilated.