(1) Injection of a low dose of haloperidol, that has no obvious behavioral effects in normal mice, produces akinesia, catalepsy, and somatosensory neglect in MPTP-treated mice.
(2) The novel anxiolytic drug, buspirone, reverses catalepsy induced by haloperidol.
(3) Indomethacin and studied prostaglandins did not influence inhibitory action of FDP on haloperidol-induced catalepsy.
(4) Both antagonists produced catalepsy as evidenced by dose-dependent increases in step- down latency.
(5) Joint administration of WA-335 and L-DOPA with an inhibitor of peripheral decarboxylase, or WA-335 and amantadine produced a stronger antagonistic effect (spiroperidol catalepsy) than either of these substances separately.
(6) Finally 6 patients undergoing DDP with Timiperone in combination with trihexyphenidyl suffered no symptoms of catalepsy but sometimes had mild vomiting episodes (1-4 times a day).
(7) Finally, Lu 19-005 antagonized the catalepsy induced by perphenazine.
(8) All rats were tested for catalepsy and at the end of the last catalepsy test, striatal DOPAC, HVA and ACh were determined.
(9) Bilateral intrastriatal injections of quinolinic acid (QA) (180 nmoles) induced weight loss and neurologic and behavioral deficits including convulsions, decreased catalepsy response to haloperidol, increased nocturnal locomotor activity, and abnormal feeding behavior in adult male Sprague-Dawley rats.
(10) Studies on the mechanism of post-etorphine catalepsy.
(11) This dose of haloperidol alone caused only a slight, gradually developing catalepsy, while alphaMT alone caused none.
(12) Administration of oxotremorine to mice produced centrally-mediated effects, such as catalepsy and tremor, and peripheral muscarinic actions, such as diarrhoea and lachrymation.
(13) The results, together with a literature survey on the anticholinergic effects on neuroleptic-induced catalepsy and inhibition of avoidance behavior, are related to biochemical findings and clinical effects.
(14) The action of opiates leading to an inhibition of flexor alpha-motoneurones may contribute to akinesia and catalepsy, and opioid-induced muscular rigidity.
(15) In a second experiment, thioridazine, dopamine, norepinephrine, serotonin and their metabolites were assayed in the brain of the rat after acute administration of the enantiomers of thioridazine and the assessment of catalepsy.
(16) When the catalepsy score was almost maximal (60 s, measured by the bar-test), the rats were handled, exposed to cold (3 degrees C) or immobilized.
(17) A series of aryl-piperazine analogues of buspirone and other 5-hydroxytryptaminergic agonists were tested for their ability to reverse haloperidol induced catalepsy.
(18) MK-801 also potentiated the anticataleptic effect of scopolamine and bromocriptine against haloperidol-induced catalepsy.
(19) Striatal dopamine (DA) stores were only minimally depleted at the time of catalepsy potentiation.
(20) Catalepsy, measured by the duration of loss of righting reflex (DLRR) in catatonic animals, was induced by larger doses of both ketamine and morphine and in each case was reduced by a larger dose of naloxone.
Fixation
Definition:
(n.) The act of fixing, or the state of being fixed.
(n.) The act of uniting chemically with a solid substance or in a solid form; reduction to a non-volatile condition; -- said of gaseous elements.
(n.) The act or process of ceasing to be fluid and becoming firm.
(n.) A state of resistance to evaporation or volatilization by heat; -- said of metals.
Example Sentences:
(1) These results are discussed in relation to the possible existence of enzyme-bound intermediates of nitrogen fixation.
(2) The way how to apply this fixator is described in details.
(3) Good fixation was obtained in 4 cases using Steffee's devices.
(4) Eighty-eight patients (97%) had a stable fixation and 77 (85%) had resumed preoperative activity or were working but with a residual deficit.
(5) Internal fixation of these pathological fractures appeared to be the best treatment.
(6) In open fractures especially in those with severe soft tissue damage, fracture stabilisation is best achieved by using external fixators.
(7) To selectively stain polyanionic macromolecules of growth plate cartilage and to prevent artifacts induced by aqueous fixation, proximal tibial growth plates were excised from rats, slam-frozen, and freeze-substituted in 100% methanol containing the cationic dye Alcian blue.
(8) The fracture can be treated arthroscopically by rigid internal fixation, while at the same time treating possible associated lesions.
(9) Total excision and immediate reconstruction were done with alloplastic material fixated with microplates and screws.
(10) These antibodies are usually characterized by the conventional platelet complement fixation test.
(11) Viruses isolated from ticks (Ixodes uriae) from a seabird colony on the Isle of May, Scotland, were shown by complement fixation tests to be related to the Uukuniemi and Kemerovo serogroups.
(12) Since 1984, 16 children (mean age 10.3 years) have had stabilization of their femoral shaft fractures by external fixation (Monofixateur) in the Trauma Department of the Hannover Medical School.
(13) Studies were undertaken to improve the production of histoplasmin for use in complement-fixation tests and in the determination of H and M antibodies.
(14) Effects of fixation with glutaraldehyde (GA), glutaraldehyde-osmium tetroxide (GA-OsO(4)), and osmium tetroxide (OsO(4)) on ion and ATP content, cell volume, vital dye staining, and stability to mechanical and thermal stress were studied in Ehrlich ascites tumor cells (EATC).
(15) Serology represents the primary method, using the techniques of complement fixation, indirect immunofluorescence, and enzyme-linked immunosorbent assay (ELISA).
(16) We found that the Gallie system generally allowed significantly more rotation in flexion, extension, axial rotation, and lateral bending than the other three fixation techniques.
(17) Good correlation was obtained with results of complement fixation tests, whereas double diffusion in gel was less sensitive.
(18) At 4 degrees C or after fixation, anti-renal tubular brush border vesicle (BBV) IgG bound diffusely to the surface of GEC and to coated pits.
(19) Eight patients with infected nonunions had initial debridement procedures; three of these patients then had placement of external fixators and bone grafting.
(20) In difficult fractures we feel that change from external to internal fixation should be performed earlier; it makes early removal of the fixator pins possible and prevents the problems associated with prolonged use of fixator frames.