(n.) The curve formed by a rope or chain of uniform density and perfect flexibility, hanging freely between two points of suspension, not in the same vertical line.
Example Sentences:
(1) Following percutaneous administration, the drug seems to be absorbed catenary to some degree.
(2) Two model structures, mammillary and catenary, were fitted to the data.
(3) Tissue loading was determined using a previously verified model of the capsule that represents its upper edge as a catenary suspension cable.
(4) A catenary process of development of orientation selectivity is proposed, the immature compartment being a transit pool between non-specific and specific cells.
(5) A theory is developed, for drugs that can be described by pure catenary pharmacokinetic models, which enables one to quantitatively determine at what time a cyclic infusion of drug should be initiated, what the frequency of infusion should be, and what the amplitude of the infusion should be to obtain maximum therapeutic benefit at steady state.
(6) Two mandibular arch forms, the catenary and the Bonwill-Hawley, were examined.
(7) As examples, the method is applied to mammillary and catenary models.
(8) This theoretical analysis suggested that in vitro nitrate action is mediated by a catenary process, consistent with published biochemical evidence that suggests a series of reactions involving metabolic activation to nitric oxide, production of cyclic GMP, and myosin light-chain phosphorylation to produce relaxation.
(9) Elimination of the drug by metabolism and excretion was described by a catenary model.
(10) Polynomial and catenary equations were fit by least square error methods to the dentitions of seven children with "normal" occlusion.
(11) As an example, the expression of D for mammillary and catenary pharmacokinetic models is derived.
(12) The method is applicable to catenary metabolites with any precursor order and does not require separate administration of the metabolite.
(13) The model consists of a catenary system of a biorhythmic control, the adrenal gland, and a body compartment containing circulating cortisol.
(14) A catenary turnover model is proposed, which links in vivo erythrocyte labile cholesterol and plasma esterified cholesterol.
(15) 45Ca desaturation from rat kidney slices can be analyzed as in an open three-compartment catenary system.
(16) This approach, which treats excretion as the 'last' compartment of all catenary metabolic pathways, avoids the use of convolution integrals and provides algebraic solutions that can be programmed on hand held calculators or personal computers.
(17) There was no synthesis in pool 3 using a mammillary model but a mean 5.3 percent of the total body production rate was found in compartment 3 if a catenary model was assumed.
(18) (The catenary is found in nature as the approximate shape taken by a flexible cable when it is suspended at two points).
(19) The hydrolysis rate of the acetate ester moiety was found to be slow, with a minimum in the pH-rate catenary at approximately pH 3.5.
(20) Although a catenary model is biologically unlikely, it could not be excluded.
Catenate
Definition:
(v. t.) To connect, in a series of links or ties; to chain.
Example Sentences:
(1) A tabulation is given of the polynomials for all possible stereoisomers of many of the knotted and catenated forms that are found in DNA.
(2) We present a unified model for the relaxation, catenation, and knotting reactions of topoisomerase I in which the enzyme induces a break in a single-stranded region, but bridges that break with covalent and noncovalent interactions and allows passage of one duplex or single-stranded DNA segment.
(3) Unlike Escherichia coli topoisomerase I (omega), catenation by the HeLa topoisomerase I is not stimulated by gapped circles.
(4) Both the relaxation and the catenation reaction exhibit a salt optimum at 130 mM NaCl.
(5) Our findings suggest the need for closer examination for HPV episomal catenation in other cervical carcinoma cell lines as well as in primary carcinoma tissues of the uterine cervix and the anogenital tract.
(6) At low concentrations of Topo I (sufficient to confer specificity to the replication system for DNA templates containing a ColE1-type origin of DNA replication), the major products of the replication reaction were: multigenome-length, linear, double-stranded DNA molecules (an aberrant product); multiply interlinked, catenated, supercoiled DNA dimers; and a last Cairns-type replication intermediate.
(7) The increase in the number of TR in progeny episomes indicates that linear DNA is produced from concatameric replicative intermediates rather than from amplified catenated circular intermediates.
(8) Crude extracts and partially purified fractions contain an aggregating factor that can substitute spermidine in catenating reactions.
(9) Upon centrifugation of gently lysed T. cruzi cells through a sucrose gradient, a free DNA fraction was shown to contain catenated dimers and knotted DNA structures.
(10) The mitochondrial DNA of trypanosomes is organized as a network of catenated circular DNA molecules called the kinetoplast.
(11) Unexpectedly, deletion of the first Zn finger, a point mutation in the Zn-catenation site in the first finger, or one in the steroid-specificity domain at the base of the first finger converted GR into a dexamethasone-responsive activator that enhanced basal and interleukin 1-induced IL-6 promoter function.
(12) The results are consistent with the idea that DNA-binding sites are fixed on the scaffold and mediate catenation of bound DNA circles by holding them in close proximity to each other.
(13) Ellipticine in particular produced these catenated dimers rapidly and efficiently.
(14) Consequently, the relaxation activity was almost the same between the RL and AH fractions, whereas the catenation activity was much higher in the AH fraction.
(15) For a DNA circle nicked at a unique location, the efficiency of DNA breakage opposite the nick correlates with the rate of catenation.
(16) This procedure liberates linearized minicircle molecules from network catenation, distributing them throughout the lysate, and allowing a small aliquot of the original lysate to be analyzed by PCR amplification.
(17) In vitro, the complexity of catenated products was linearly proportional to substrate supercoil density.
(18) These newly synthesized strands were not part of two catenated interlocked SV40 monomers suggesting that the block occurred prior to the final ligation reaction.
(19) Hypertonic medium appeared to inhibit both DNA unwinding in the termination region and separation of catenated dimers.
(20) MtDNA (monomeric and catenated dimeric forms) in transformed and uninfected CEF replicate by displacement synthesis.