(n.) Connection of links or union of parts, as in a chain; a regular or connected series. See Concatenation.
Example Sentences:
(1) A tabulation is given of the polynomials for all possible stereoisomers of many of the knotted and catenated forms that are found in DNA.
(2) We present a unified model for the relaxation, catenation, and knotting reactions of topoisomerase I in which the enzyme induces a break in a single-stranded region, but bridges that break with covalent and noncovalent interactions and allows passage of one duplex or single-stranded DNA segment.
(3) Unlike Escherichia coli topoisomerase I (omega), catenation by the HeLa topoisomerase I is not stimulated by gapped circles.
(4) Both the relaxation and the catenation reaction exhibit a salt optimum at 130 mM NaCl.
(5) Our findings suggest the need for closer examination for HPV episomal catenation in other cervical carcinoma cell lines as well as in primary carcinoma tissues of the uterine cervix and the anogenital tract.
(6) At low concentrations of Topo I (sufficient to confer specificity to the replication system for DNA templates containing a ColE1-type origin of DNA replication), the major products of the replication reaction were: multigenome-length, linear, double-stranded DNA molecules (an aberrant product); multiply interlinked, catenated, supercoiled DNA dimers; and a last Cairns-type replication intermediate.
(7) The increase in the number of TR in progeny episomes indicates that linear DNA is produced from concatameric replicative intermediates rather than from amplified catenated circular intermediates.
(8) Crude extracts and partially purified fractions contain an aggregating factor that can substitute spermidine in catenating reactions.
(9) Upon centrifugation of gently lysed T. cruzi cells through a sucrose gradient, a free DNA fraction was shown to contain catenated dimers and knotted DNA structures.
(10) The mitochondrial DNA of trypanosomes is organized as a network of catenated circular DNA molecules called the kinetoplast.
(11) Unexpectedly, deletion of the first Zn finger, a point mutation in the Zn-catenation site in the first finger, or one in the steroid-specificity domain at the base of the first finger converted GR into a dexamethasone-responsive activator that enhanced basal and interleukin 1-induced IL-6 promoter function.
(12) The results are consistent with the idea that DNA-binding sites are fixed on the scaffold and mediate catenation of bound DNA circles by holding them in close proximity to each other.
(13) Ellipticine in particular produced these catenated dimers rapidly and efficiently.
(14) Consequently, the relaxation activity was almost the same between the RL and AH fractions, whereas the catenation activity was much higher in the AH fraction.
(15) For a DNA circle nicked at a unique location, the efficiency of DNA breakage opposite the nick correlates with the rate of catenation.
(16) This procedure liberates linearized minicircle molecules from network catenation, distributing them throughout the lysate, and allowing a small aliquot of the original lysate to be analyzed by PCR amplification.
(17) In vitro, the complexity of catenated products was linearly proportional to substrate supercoil density.
(18) These newly synthesized strands were not part of two catenated interlocked SV40 monomers suggesting that the block occurred prior to the final ligation reaction.
(19) Hypertonic medium appeared to inhibit both DNA unwinding in the termination region and separation of catenated dimers.
(20) MtDNA (monomeric and catenated dimeric forms) in transformed and uninfected CEF replicate by displacement synthesis.
Ring
Definition:
(v. t.) To cause to sound, especially by striking, as a metallic body; as, to ring a bell.
(v. t.) To make (a sound), as by ringing a bell; to sound.
(v. t.) To repeat often, loudly, or earnestly.
(v. i.) To sound, as a bell or other sonorous body, particularly a metallic one.
(v. i.) To practice making music with bells.
(v. i.) To sound loud; to resound; to be filled with a ringing or reverberating sound.
(v. i.) To continue to sound or vibrate; to resound.
(v. i.) To be filled with report or talk; as, the whole town rings with his fame.
(n.) A sound; especially, the sound of vibrating metals; as, the ring of a bell.
(n.) Any loud sound; the sound of numerous voices; a sound continued, repeated, or reverberated.
(n.) A chime, or set of bells harmonically tuned.
(n.) A circle, or a circular line, or anything in the form of a circular line or hoop.
(n.) Specifically, a circular ornament of gold or other precious material worn on the finger, or attached to the ear, the nose, or some other part of the person; as, a wedding ring.
(n.) A circular area in which races are or run or other sports are performed; an arena.
(n.) An inclosed space in which pugilists fight; hence, figuratively, prize fighting.
(n.) A circular group of persons.
(n.) The plane figure included between the circumferences of two concentric circles.
(n.) The solid generated by the revolution of a circle, or other figure, about an exterior straight line (as an axis) lying in the same plane as the circle or other figure.
(n.) An instrument, formerly used for taking the sun's altitude, consisting of a brass ring suspended by a swivel, with a hole at one side through which a solar ray entering indicated the altitude on the graduated inner surface opposite.
(n.) An elastic band partly or wholly encircling the spore cases of ferns. See Illust. of Sporangium.
(n.) A clique; an exclusive combination of persons for a selfish purpose, as to control the market, distribute offices, obtain contracts, etc.
(v. t.) To surround with a ring, or as with a ring; to encircle.
(v. t.) To make a ring around by cutting away the bark; to girdle; as, to ring branches or roots.
(v. t.) To fit with a ring or with rings, as the fingers, or a swine's snout.
(v. i.) To rise in the air spirally.
Example Sentences:
(1) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(2) Sterile, pruritic papules and papulopustules that formed annular rings developed on the back of a 58-year-old woman.
(3) The teeth were embedded in phenolic rings with acrylic resin.
(4) Surgical removal was avoided without complications by detaching it with a ring stripper.
(5) The Labour MP urged David Cameron to guarantee that officers who give evidence over the alleged paedophile ring in Westminster will not be prosecuted.
(6) These results coupled with previous studies support activation of benz[j]aceanthrylene via both 2 and cyclopenta ring epoxidation.
(7) TK1 showed the most restricted substrate specificity but tolerated 3'-modifications of the sugar ring and some 5-substitutions of the pyrimidine ring.
(8) Endothelium-dependent relaxations to acetylcholine and endothelium-independent relaxations to nitric oxide were observed in rings from both strains during contraction with endothelin.
(9) Aortic rings from the rabbit were similarly potently antagonized by the protein kinase C inhibitors, however, K(+)-induced contractions were also equally sensitive to these agents in both rat and rabbit tissues.
(10) The intracellular distribution and interaction of 19S ring-type particles from D. melanogaster have been analysed.
(11) Rings of isolated coronary and femoral arteries (without endothelium) were suspended for isometric tension recording in organ chambers filled with modified Krebs-Ringer bicarbonate solution.
(12) In all cases Richter's hernia was at the internal inguinal ring.
(13) Seventy-five hands showed normal distal latency, in which cases, however, the SNCV of the ring finger was always outside the normal range, while the SNCVs of the thumb, index and middle fingers were abnormal in 64%, 80% and 92% of cases respectively.
(14) The cells are predominantly monopolar, tightly packed, and are flattened at the outer border of the ring.
(15) Defects in the posterior one-half of the trachea, up to 5 rings long, were repaired, with minimal stenosis.
(16) A new analog of salmon calcitonin (N alpha-propionyl Di-Ala1,7,des-Leu19 sCT; RG-12851; here termed CTR), which lacks the ring structure of native calcitonin, was tested for biological activity in several in vitro and in vivo assay systems.
(17) The chemical shift changes observed on the binding of trimethoprim to dihydrofolate reductase are interpreted in terms of the ring-current shift contributions from the two aromatic rings of trimethoprim and from that of phenylalanine-30.
(18) Three strains of fluorescent pseudomonads (IS-1, IS-2, and IS-3) isolated from potato underground stems with roots showed in vitro antibiosis against 30 strains of the ring rot bacterium Clavibacter michiganensis subsp.
(19) Both adiphenine.HCl and proadifen.HCl form more stable complexes, suggesting that hydrogen bonding to the carbonyl oxygen by the hydroxyl-group on the rim of the CD ring could be an important contributor to the complexation.
(20) Serial sections from over a hundred such structures show that these are tubular structures and that the 'test-tube and ring-shaped' forms described in the literature are no more than profiles one expects to see when a tubular structure is sectioned.