What's the difference between cell and senescence?

Cell


Definition:

  • (n.) A very small and close apartment, as in a prison or in a monastery or convent; the hut of a hermit.
  • (n.) A small religious house attached to a monastery or convent.
  • (n.) Any small cavity, or hollow place.
  • (n.) The space between the ribs of a vaulted roof.
  • (n.) Same as Cella.
  • (n.) A jar of vessel, or a division of a compound vessel, for holding the exciting fluid of a battery.
  • (n.) One of the minute elementary structures, of which the greater part of the various tissues and organs of animals and plants are composed.
  • (v. t.) To place or inclose in a cell.

Example Sentences:

  • (1) The variation in thickness of the LLFL may modulate the species causing damage to the cells below it.
  • (2) Similar experimental manipulation has yielded in vitro lines established from avian B-cell lymphomas expressing elevated levels of c-myc or v-rel.
  • (3) A spindle cell sarcoma appeared 20 months after implantation of a pellet of 3-methylcholanthrene in the denervated foreleg of an adult frog, Rana pipiens.
  • (4) The effect of insulin-like growth factor I (IGF-I) on growth of small cell lung cancer (SCLC) cell lines was studied.
  • (5) The patterns observed were: clusters of granules related to the cell membrane; positive staining localized to portions of the cell membrane, and, less commonly, the whole cell circumference.
  • (6) This study was undertaken to determine whether the survival of Hispanic patients with squamous cell carcinoma of the head and neck was different from that of Anglo-American patients.
  • (7) This suggested that the chemical effects produced by shock waves were either absent or attenuated in the cells, or were inherently less toxic than those of ionizing irradiation.
  • (8) Patients with papillary carcinoma with a good cell-mediated immune response occurred with much lower infiltration of the tumor boundary with lymphocyte whereas the follicular carcinoma less cell-mediated immunity was associated with dense lymphocytic infiltration, suggesting the biological relevance of lymphocytic infiltration may be different for the two histologic variants.
  • (9) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
  • (10) Assessment of the likelihood of replication in humans has included in vitro exposure of human cells to the potential pesticidal agent.
  • (11) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
  • (12) Steady-state values of cell, glucose, and cellulase concentration oxygen tension, and outlet gas oxygen partial pressure were recorded.
  • (13) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
  • (14) Within the outflow tract wall, the labelled cells were enmeshed by strands of alcian blue-stained extracellular matrix.
  • (15) Neutrons induced a dose-dependent cytotoxicity and mutation frequency in the AL cells.
  • (16) After stimulation with lipopolysaccharide and calcium ionophore A23187, culture supernatants of clones c18A and c29A showed cytotoxic activity against human melanoma A375 Met-Mix and other cell lines which were resistant to the tumor necrosis factor, lymphotoxin and interleukin 1.
  • (17) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
  • (18) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
  • (19) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
  • (20) Apparently, the irradiation with visible light of a low intensity creates an additional proton gradient and thus stimulates a new replication and division cycle in the population of cells whose membranes do not have delta pH necessary for the initiation of these processes.

Senescence


Definition:

  • (n.) The state of growing old; decay by time.

Example Sentences:

  • (1) The proliferation of this cell type may represent an escape from the senescence pathway and progression to immortal tumor cells.
  • (2) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
  • (3) In addition, we have shown that long-lived, presumably non-senescent, strains do not arise by suppressor mutation, but lose senescence plasmid DNA by another mechanism.
  • (4) Senescent (26-28 months) Fischer 344 rats were shown to have a lower density of D2 sites (-36%) without any change in affinity in membranes prepared from homogenized caudate-putamen (CPU), as compared to young adult (5-6 months) rats.
  • (5) The cell cycle-dependent changes in the transglutaminase mRNA levels strongly support the implicated involvement of the enzyme in cell growth, differentiation, and senescence.
  • (6) The increased levels of HK1 could affect other erythrocyte metabolic pathways slowing down the physiological rate of cellular senescence and result in increased activity levels of other cell-age-dependent enzymes.
  • (7) Advancing age was associated with a reduction in cell proliferative responses to PHA in both substrains, although the rate of decline was significantly more rapid in the senescence-prone animals.
  • (8) Instead of degenerative changes, these results show an activation of the vasopressinergic system in senescence and in SDAT patients, similar to earlier observations in the aged rat and in accordance with a rise in human neurophysin and VP levels reported recently.
  • (9) Thus, constitutive expression of specific cytochrome P450 genes is repressed or activated in senescent rats.
  • (10) Mild daily exercise, maintained throughout adult life into early senescence, attenuates muscle atrophy and promotes adaptive enzymatic changes in atrophying muscles.
  • (11) A second set of experiments which involved the injection of E2 into senescent male as well as female rats indicated that there were no sex differences in improvements in inclined screen performance, and that once the E2 injections were discontinued, performance returned to preadministration levels.
  • (12) Additionally, analysis of the multiple steps occurring in the El cultures, as well as in the emergence of the continuous cell lines, could potentially elucidate the processes occurring during human epithelial cell carcinogenesis and escape from senescence.
  • (13) Significant anamnestic SIgA responses were shown after oral immunization with DNP-BGG in adult rats, but was not observed in the senescent and midlife (10-12 months) rats.
  • (14) Modulation of cellular senescence by growth factors, hormones, and genetic manipulation is contrasted, but newer studies in oncogene involvement are omitted.
  • (15) Under the same conditions, PM from senescent mice generated 62% of the initial O2- produced in response to zymosan, and 45% in response to OZ.
  • (16) Untreated cells, or cells treated with MCA or TPA only, usually became senescent around 6-8 weeks after plating and died, but those treated with both MCA and TPA became immortalised and underwent transformation to a phenotype capable of growth in soft agar.
  • (17) Because immune senescence most profoundly affects T lymphocyte functions, we suspected that LIA production would decline with age.
  • (18) Abnormal granular structures, which stained positively with periodic acid-Schiff (PAS-positive granular structures; PGS), were observed in the brain of senescence accelerated mouse (SAM).
  • (19) In senescent females the number of small IMPs was decreased in the perikarya and dendritic shafts compared to young females while the number of large particles was increased in the outer leaflet of the membrane of dendritic shafts, reaching values similar to those observed in males.
  • (20) Our data suggest that the release of u-PA antigen by human macrovascular endothelial cells can be used as an indicator of cell senescence.

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