(1) [125I]ET-1 binding to ETB receptors (nonselective to ET isopeptides) in cerebellar membranes was not inhibited by either of these compounds even at 100 microM.
(2) The deep cerebellar nuclei were moderately labeled at birth and gradually decreased in density thereafter.
(3) In the 2nd family, several members had cerebellar signs, chorea, and dementia.
(4) This paper provides a description of the cerebellar-vestibular-determined (CV) neurological and electronystagmographic (ENG) parameters characterizing 4,000 patients with learning disabilities.
(5) We report the case of a premature infant, small for gestational age, who experienced rostral herniation of a portion of frontal lobe through the anterior fontanel as the result of a hemorrhagic cerebellar infarction followed by a large parieto-occipital intracerebral hemorrhage.
(6) Reduced uptake was observed in the left cerebral hemisphere (-13.9%) contralateral to the cerebellar infarction with the most marked reduction in the left premotor region (-21%).
(7) Peak incorporation into cerebellar synaptoneurosomal fractions was at 60 minutes following intraventricular injection.
(8) The inositol 1,4,5-trisphosphate (IP3) binding inhibitor, heparin, has no effect on ryanodine binding, and ryanodine and caffeine do not influence the binding of [3H]IP3, which is enriched in the cerebellar fractions.
(9) The use of a brief perfusion of 0.32 M sucrose improved the quality of the cryofixation and allowed the study of the deeper layers of the cerebellar cortex.
(10) Several months later, as the patient experienced relapses with cerebellar and spinal cord involvement, falsely positive tests for syphilis were found and an antibiotic treatment was given.
(11) The organization of the afferent and efferent connections of the sagittal Zones A and B of the cerebellar cortex of the rat have been studied using wheat-germ agglutinin conjugated to horseradish peroxidase as a tracer.
(12) At hospitalization, the examination also revealed cerebellar metastasis.
(13) The apparent localisation of the two main receptor differences (high-affinity [3H]muscimol binding and diazepam sensitivity of [3H]Ro 15-4513 binding) to the cerebellar granule layer suggests a genetic modification in the granule cells of alcohol-sensitive rats.
(14) On admission, neurological examination revealed staggering gait and the right cerebellar ataxia showing dysmetria and dysdiadochokinesis.
(15) One patient harbored a basilar trunk aneurysm, 1 an aneurysm of the proximal posterior cerebral artery, 3 an aneurysm of the superior cerebellar artery, and 10 an aneurysm at the basilar tip.
(16) [2-3H]Mannose incorporation into cerebellar glycoproteins was greater in malnourished rats during the period of brain growth spurt than in normally fed rats at all ages studied.
(17) The interposed nuclei projected mainly to the paravermis-medial hemispheric zone of the cerebellar cortex.
(18) Since cholinergic transmission is probably insignificant in the cerebellar cortex, the esterase itself might serve as a transmitter or modulator.
(19) Characteristics of the poisoning include a delay between exposure and onset of symptoms; early systemic toxicity with congestive changes in the lungs and oliguric renal failure; prominent cerebellar and Parkinsonian neurologic symptoms as well as seizures and coma in severe cases; and psychiatric disturbances that can last from months to years.
(20) In addition, Alcian Blue (AB) staining was applied to mouse cerebellar tissue in order to study glycosaminoglycan histochemistry.
Cerebellum
Definition:
(n.) The large lobe of the hind brain in front of and above the medulla; the little brain. It controls combined muscular action. See Brain.
Example Sentences:
(1) The presence of CR-related activity suggests that SpoV may participate in the CR motor output pathway, and may also provide CR-related information to cerebellum.
(2) No HRP-labeled axons were found in the facial and solitary nuclei and the cerebellum.
(3) Blood flows to contralateral cerebral hemispheric structures were relatively unchanged from prehypoxic values, whereas flows to the brainstem and cerebellum nearly doubled and tripled, respectively.
(4) The cerebellum was almost intact except for a few amyloid plaques.
(5) In general, the cerebellum showed a much delayed developmental pattern with regard to Purkinje cell spine formation.
(6) Incomplete penetrance of the simpler pattern suggests that this genetic locus interacts in a probabilistic manner with epigenetic mechanisms involved in morphogenesis of the cerebellum.
(7) The temporal changes in subunit messenger RNA levels in the cerebellum raise the possibility that synaptogenesis may play a role in receptor gene regulation in this brain region.
(8) Unexpectedly long retention times were noted for the chlorinated solvents, particularly for chloroforn, which showed a specific long-term retention in the cerebellum, meninges and spinal nerves, indicating interactions with specific nervous tissue receptors.
(9) Cells dissociated from 6-day rat cerebellum were seeded on glass coverslips coated with polylysine on one half and hyaluronectin on the other.
(10) Northern blot analyses showed no change in ubiquitin or PGP9.5 gene expression in hippocampus or cerebellum.
(11) Moderately higher GLUT3 mRNA levels were detected in the parietal lobe of the cerebrum, hippocampus, and cerebellum than the levels of GLUT1 transcripts.
(12) In the normal 79-day-old mouse cerebellum, the highest concentration of [3H]muscimol binding sites was observed in the granule cell layer.
(13) Fluorescent labels, injected into either the hindlimb muscles or the cerebellum, are retrogradely transported to motoneurones or dorsal spinocerebellar tract neurones respectively.
(14) The autonomic centers in the brain-stem and cerebellum were systematically affected in both the sporadic and the hereditary cases.
(15) Using an affinity-purified antiserum raised against the p36 heavy chain from bovine adrenal medulla, we have examined the cellular distribution of p36 in developing and adult cerebellum.
(16) Neutral aminopeptidase activity showed a significant decrease in the thalamus and cerebellum with marked (not significant) changes in the hypothalamus, hippocampus, medulla, and occipital cortex.
(17) cerebellum, basal ganglia and hypothalamus, reveal selectivity that fails to conform to conventional descriptions of functional systems.
(18) Tracking a moving target with the index finger defined a network of focal responses of relative cerebral blood flow (relCBF) located in the primary motor cortex, dorsal parietal cortex, precuneate cortex, supplementary motor area (SMA) and ipsilateral anterior cerebellum relative to visual tracking alone.
(19) Naloxone-displaceable binding was observed in all regions of the brain, with a density ranking order of cerebellum greater than telencephalon greater than optic tectum greater than hypothalamus greater than brain stem greater than pituitary gland.
(20) The potency of several selective and non-selective ligands for benzodiazepine receptors for inhibition of the binding of [3H]flunitrazepam was compared in membranes from human or rat brain cerebellum, hippocampus and cerebral cortex.