(n.) The large lobe of the hind brain in front of and above the medulla; the little brain. It controls combined muscular action. See Brain.
Example Sentences:
(1) The presence of CR-related activity suggests that SpoV may participate in the CR motor output pathway, and may also provide CR-related information to cerebellum.
(2) No HRP-labeled axons were found in the facial and solitary nuclei and the cerebellum.
(3) Blood flows to contralateral cerebral hemispheric structures were relatively unchanged from prehypoxic values, whereas flows to the brainstem and cerebellum nearly doubled and tripled, respectively.
(4) The cerebellum was almost intact except for a few amyloid plaques.
(5) In general, the cerebellum showed a much delayed developmental pattern with regard to Purkinje cell spine formation.
(6) Incomplete penetrance of the simpler pattern suggests that this genetic locus interacts in a probabilistic manner with epigenetic mechanisms involved in morphogenesis of the cerebellum.
(7) The temporal changes in subunit messenger RNA levels in the cerebellum raise the possibility that synaptogenesis may play a role in receptor gene regulation in this brain region.
(8) Unexpectedly long retention times were noted for the chlorinated solvents, particularly for chloroforn, which showed a specific long-term retention in the cerebellum, meninges and spinal nerves, indicating interactions with specific nervous tissue receptors.
(9) Cells dissociated from 6-day rat cerebellum were seeded on glass coverslips coated with polylysine on one half and hyaluronectin on the other.
(10) Northern blot analyses showed no change in ubiquitin or PGP9.5 gene expression in hippocampus or cerebellum.
(11) Moderately higher GLUT3 mRNA levels were detected in the parietal lobe of the cerebrum, hippocampus, and cerebellum than the levels of GLUT1 transcripts.
(12) In the normal 79-day-old mouse cerebellum, the highest concentration of [3H]muscimol binding sites was observed in the granule cell layer.
(13) Fluorescent labels, injected into either the hindlimb muscles or the cerebellum, are retrogradely transported to motoneurones or dorsal spinocerebellar tract neurones respectively.
(14) The autonomic centers in the brain-stem and cerebellum were systematically affected in both the sporadic and the hereditary cases.
(15) Using an affinity-purified antiserum raised against the p36 heavy chain from bovine adrenal medulla, we have examined the cellular distribution of p36 in developing and adult cerebellum.
(16) Neutral aminopeptidase activity showed a significant decrease in the thalamus and cerebellum with marked (not significant) changes in the hypothalamus, hippocampus, medulla, and occipital cortex.
(17) cerebellum, basal ganglia and hypothalamus, reveal selectivity that fails to conform to conventional descriptions of functional systems.
(18) Tracking a moving target with the index finger defined a network of focal responses of relative cerebral blood flow (relCBF) located in the primary motor cortex, dorsal parietal cortex, precuneate cortex, supplementary motor area (SMA) and ipsilateral anterior cerebellum relative to visual tracking alone.
(19) Naloxone-displaceable binding was observed in all regions of the brain, with a density ranking order of cerebellum greater than telencephalon greater than optic tectum greater than hypothalamus greater than brain stem greater than pituitary gland.
(20) The potency of several selective and non-selective ligands for benzodiazepine receptors for inhibition of the binding of [3H]flunitrazepam was compared in membranes from human or rat brain cerebellum, hippocampus and cerebral cortex.
Hindbrain
Definition:
(n.) The posterior of the three principal divisions of the brain, including the epencephalon and metencephalon. Sometimes restricted to the epencephalon only.
Example Sentences:
(1) These observations and a relatively high incidence of hindbrain tumours are suggestive of an embryonic origin for most of the cases.
(2) Among the 18 hindbrain areas, LCGU was decreased by pentobarbital by 15-55% (range 50-157 and 28-110 mumol.100 g-1.min-1 in control and treated rats, respectively).
(3) Under conditions of chronic or repeated seizure activity over prolonged time periods, seizures evoked from the hindbrain can recruit forebrain circuits; conversely, repeated stimulation of forebrain limbic circuits (e.g., kindling) can modify susceptibility to brainstem convulsions.
(4) These differences in effects on specific neurotransmitter systems reflect the fact that the forebrain is most severely affected by early ethanol administration, whereas the hindbrain is relatively spared.
(5) Microscopic immunohistochemical localization of CRABP found the highest concentration in the ventral midbrain and in the ventral and lateral sides of the hindbrain and spinal cord; CRABP was also abundant in tongue, limb, and skin.
(6) The question raised was whether cells from the graft would be able to yield the neural crest derivatives normally arising from the hindbrain and vagal crest, such as carotid body type I and II cells, enteric ganglia, Schwann cells located along the local nerves, and the nonneuronal contingent of cells in the host nodose ganglion.
(7) Potency profiles of these and other analogues suggest that the renal medulla and dorsal hindbrain vasopressin receptors represent different subtypes.
(8) During this period, the intensity of transcription in presomitic and somitic mesoderm declines relative to that in the overlying neural ectoderm, and the transcription boundary within the presumptive hindbrain region sharpens.
(9) In detailed examination of alpha Enhb-1 and 4D9 localization, we find previously undetected patterns of En protein localization in the prechordal plate, hindbrain, myotome, ventral body-wall mesoderm, and extraembryonic membranes.
(10) The results were as follows: (1) III-V interpeak latency (IPL) decreased progressively from prolonged to the normal range with growth until 25 years of age; (2) I-III IPL tended to prolong gradually from the normal range; (3) these findings may indicate that the natural history of Chiari II malformation is delayed maturation of the brain stem and intensification in the elongation and stretching of the hindbrain and lower cranial nerves.
(11) Both genes are expressed in the developing midbrain and its junction with the hindbrain.
(12) Both mutants also have altered polyamine synthesis and accumulation, particularly in the hindbrain and spinal column.
(13) With due consideration for the clinical findings and those recorded by Doppler ultrasound and computed tomography, vertebral angiography is indicated in vertebrobasilar occlusive disease if anticoagulation, percutaneous transluminal angioplasty (PTA) or local intraarterial fibrinolytic therapy (LIF) of the hindbrain circulation is intended, and also if there is a discrepancy between the clinical findings and the results of computed tomography or Doppler ultrasound examination.
(14) The results indicate that the mesencephalon is the principal site for the precursor cells of the ciliary ganglia and clearly rules out any contribution to the ganglia from either the forebrain or hindbrain levels.
(15) In specimens of shovelnose, Scaphirhynchus platorynchus, and Atlantic sturgeon, Acipenser oxyrhynchus, and paddlefish, Polyodon spathula, evoked potentials recorded from the hindbrain and elicited by electric fields reached maximum amplitude within the DON and decreased in amplitude through the cerebellar crest.
(16) We show that neurons whose axons reach the hindbrain first survive for a short time in culture before responding to brain-derived neurotrophic factor (BDNF).
(17) Retinoic acid (RA) and its congeners accumulate in a saturable manner in neural crest and neural crest-derived cells, in the hindbrain, and the spinal cord of mouse embryos.
(18) In general the telencephalon made greatest use of ketone bodies, whereas the hindbrain used least.
(19) However, there was a significant linear relationship between carbon dioxide tension and the percent of the microvasculature perfused in the hindbrain.
(20) Na+, K+-ATPase activity was significantly reduced in the forebrain region at the stage of mild encephalopathy (43 h after injection), while at the deeper stage of coma (43-53 h after injection) enzyme activity was further reduced in the forebrain region and was also significantly reduced in the hindbrain region.