(1) [3H]cyclohexyladenosine (CHA) and [3H]PN200-110 were used to label muscarinic and adenosine A1 receptors and L-type calcium channels, respectively.
(2) Since ADO is a metabolic substrate and a nonselective receptor agonist, while CHA is A1-selective and a poor substrate for cellular uptake, neither A2 activation nor cellular uptake altered expression of the A1 effect of exogenous ADO.
(3) R-PIA, CHA and NECA inhibited contraction in both preparations.
(4) In contrast to the relative consistency of the patterns of 3H-CHA binding in these species, 5'-nucleotidase exhibited wide variations in both the absolute amount of activity and its localization.
(5) Concomitant measurement of [3H]-CHA binding in the mesencephalic reticular formation was also carried out in order to explore the neurochemical basis of the development of tolerance.
(6) For aortic relaxation the analogues exhibited the following rank order of potency: NECA greater than adenosine greater than 2-CA greater than R-PIA greater than CHA.
(7) Regulation of c-fos protooncogene activity in rat embryonal fibroblasts (REF), E1Aad5-immortalized REF cells, and E1Aad5 + cHa-ras transformed REF cells has been investigated.
(8) Although more studies are needed, a recent report of potential utilization of nonstimulated oocytes for donor programs as well as IVF-cryopreservation was a promising new development (Cha et al.
(9) 3H-CHA and 3H-NECA binding sites are concentrated in layers 1-3 and upper layer 5 in the visual cortex of adult cats.
(10) In this paper, CDDP-CHA tried to apply for experimental bone and soft tissue sarcoma.
(11) The effect of toxin on adenosine receptors was also evaluated by measuring binding of the adenosine agonist cyclohexyladenosine (CHA).
(12) "All those vuvuzuelas must be interfering with Cha Bum-Kun's ability to remote control his robot creation - er, son - Cha Du-ri," suggests Angela K, a South Korean expat in the US.
(13) The R(-)- and S(+)-enantiomers of N6-(2-phenylisopropyl)adenosine (R-PIA and S-PIA respectively), N6-cyclohexyladenosine (CHA) and 2-chloroadenosine (CADO) caused contractions at low concentrations (0.05-2.0 microM), whereas at higher concentrations, relaxation resulted.
(14) Circular harmonic averaging (CHA), a novel, reference-independent averaging method developed by W. Kunath and H. Sack-Kongehl [1989) Ultramicroscopy 27:171-184) allows analyzing images of single molecules of the receptor in its native membrane-bound state.
(15) An unexpected finding was that R-PIA, 2-CA and CHA all induced contractions at concentrations lower than were required for relaxation, giving a biphasic dose-response curve.
(16) Concentrations to achieve half-maximum responses were 92.5 nM for 2-ClAdo, 39 nM for CHA, and 107 nM for NECA.
(17) Moreover, the addition of guanylyl-5'-imidodiphosphate, a GTP analogue, to the incubation medium reduced CHA binding by the same order of magnitude whether rats were given saline or bicuculline, suggesting that additional adenosine A1 receptors are also functionally linked to G proteins.
(18) Hippocampi from theophylline-treated animals showed a significantly greater number of [3H]CHA binding sites (apparent Bmax; 125% of control, P less than 0.05), without a significant change in binding affinity, and were more sensitive than controls to the inhibitory effects of adenosine on the population spike response.
(19) Both genes were shown to be present in haploid embryos and have been isolated from a genomic library, the exons and deduced amino acid sequences of which are presented here (salmon CHA and CHB).
(20) Accordingly, the peak in adenosine receptor binding, using (-)[125I]iodo-N6-hydroxyphenyl-isopropyladenosine as the radioligand, coincided with CHA-inhibitable adenylate cyclase activity.
Cham
Definition:
(v. t.) To chew.
(n.) The sovereign prince of Tartary; -- now usually written khan.
Example Sentences:
(1) Ronny Cham, who represented Miss Hawkins in court, said she was relieved to be returning home.
(2) A distinct pool of liver ferritin has been described in man, guinea pigs and rats [Cham, Roeser, Nikles & Ridgway (1986) Clin.
(3) Walking the circular viewing deck, visitors start with horrific scenes from the Cham War between the Khmers and the Vietnamese before moving on to the construction of the famous Bayon Temple and ending with the daily life of Khmers.
(4) Facebook Twitter Pinterest Defence lawyer Ronny Cham Cham pleaded for leniency: “Your honour, they were ignorant of the culture, tradition and belief of the local people … including the people of Sabah and Malaysia … This is a group of a young generation … who have more freedom and liberty to express their thoughts and ideas.” Cham said the four stripped as they were “challenging one another to stand the cold of the mountain, to stand the temperature, which was near zero degrees”.
(5) Kolo Cham grows sorghum and corn near the Baro river, a 30-minute walk from his family home at Karmi.
(6) Sheikh Tayeb Mustapha Cham, imam and founder of the Taiba Welfare Foundation, said some imams still resisted condemning FGM, but religious leaders had a responsibly to speak out.
(7) Pharmacological activities of Eschscholtzia californica Cham.
(8) "Nobody would believe that such a luxury car would come to Cambodia," said the minister for industry and handcrafts, Cham Prasidh, who was present for the announcement.
(9) A technique described by Cham and Knowles allows the extraction of plasma phospholipides, triglycerides, cholesterol and free fatty acids without denaturing the proteins.
(10) Hawkins’s defence lawyer, Ronny Cham, said: “This is a happy ending to the whole episode.” He said he expected all four tourists to be deported after they had paid the fines.