(1) [3H]cyclohexyladenosine (CHA) and [3H]PN200-110 were used to label muscarinic and adenosine A1 receptors and L-type calcium channels, respectively.
(2) Since ADO is a metabolic substrate and a nonselective receptor agonist, while CHA is A1-selective and a poor substrate for cellular uptake, neither A2 activation nor cellular uptake altered expression of the A1 effect of exogenous ADO.
(3) R-PIA, CHA and NECA inhibited contraction in both preparations.
(4) In contrast to the relative consistency of the patterns of 3H-CHA binding in these species, 5'-nucleotidase exhibited wide variations in both the absolute amount of activity and its localization.
(5) Concomitant measurement of [3H]-CHA binding in the mesencephalic reticular formation was also carried out in order to explore the neurochemical basis of the development of tolerance.
(6) For aortic relaxation the analogues exhibited the following rank order of potency: NECA greater than adenosine greater than 2-CA greater than R-PIA greater than CHA.
(7) Regulation of c-fos protooncogene activity in rat embryonal fibroblasts (REF), E1Aad5-immortalized REF cells, and E1Aad5 + cHa-ras transformed REF cells has been investigated.
(8) Although more studies are needed, a recent report of potential utilization of nonstimulated oocytes for donor programs as well as IVF-cryopreservation was a promising new development (Cha et al.
(9) 3H-CHA and 3H-NECA binding sites are concentrated in layers 1-3 and upper layer 5 in the visual cortex of adult cats.
(10) In this paper, CDDP-CHA tried to apply for experimental bone and soft tissue sarcoma.
(11) The effect of toxin on adenosine receptors was also evaluated by measuring binding of the adenosine agonist cyclohexyladenosine (CHA).
(12) "All those vuvuzuelas must be interfering with Cha Bum-Kun's ability to remote control his robot creation - er, son - Cha Du-ri," suggests Angela K, a South Korean expat in the US.
(13) The R(-)- and S(+)-enantiomers of N6-(2-phenylisopropyl)adenosine (R-PIA and S-PIA respectively), N6-cyclohexyladenosine (CHA) and 2-chloroadenosine (CADO) caused contractions at low concentrations (0.05-2.0 microM), whereas at higher concentrations, relaxation resulted.
(14) Circular harmonic averaging (CHA), a novel, reference-independent averaging method developed by W. Kunath and H. Sack-Kongehl [1989) Ultramicroscopy 27:171-184) allows analyzing images of single molecules of the receptor in its native membrane-bound state.
(15) An unexpected finding was that R-PIA, 2-CA and CHA all induced contractions at concentrations lower than were required for relaxation, giving a biphasic dose-response curve.
(16) Concentrations to achieve half-maximum responses were 92.5 nM for 2-ClAdo, 39 nM for CHA, and 107 nM for NECA.
(17) Moreover, the addition of guanylyl-5'-imidodiphosphate, a GTP analogue, to the incubation medium reduced CHA binding by the same order of magnitude whether rats were given saline or bicuculline, suggesting that additional adenosine A1 receptors are also functionally linked to G proteins.
(18) Hippocampi from theophylline-treated animals showed a significantly greater number of [3H]CHA binding sites (apparent Bmax; 125% of control, P less than 0.05), without a significant change in binding affinity, and were more sensitive than controls to the inhibitory effects of adenosine on the population spike response.
(19) Both genes were shown to be present in haploid embryos and have been isolated from a genomic library, the exons and deduced amino acid sequences of which are presented here (salmon CHA and CHB).
(20) Accordingly, the peak in adenosine receptor binding, using (-)[125I]iodo-N6-hydroxyphenyl-isopropyladenosine as the radioligand, coincided with CHA-inhibitable adenylate cyclase activity.
Char
Definition:
(n.) Alt. of Charr
(n.) A car; a chariot.
(n.) Work done by the day; a single job, or task; a chore.
(v. t.) Alt. of Chare
(v. i.) Alt. of Chare
(n.) To reduce to coal or carbon by exposure to heat; to reduce to charcoal; to burn to a cinder.
(n.) To burn slightly or partially; as, to char wood.
Example Sentences:
(1) Angioscopy provided cross-sectional topographic views of thrombosed lumen and showed charring and shrinkage of thrombus following laser angioplasty.
(2) After spraying the plates with phosphoric acid and heating, the amount of carbon from the charred compounds is measured densitometrically.
(3) The frontal cortex, hippocampus, and basal ganglia were dissected at -15 degrees C. The lipids were separated by column and high-performance thin-layer chromatography and quantified by charring and densitometry.
(4) The body of one of the men was reportedly found charred and lying on a cot.
(5) It posted photos on its website of what it said was Thargyal's charred body covered in ceremonial yellow silk scarves and hundreds of people marching up a hill to a cremation site where his remains were burned.
(6) The activity of germination factor was resistant to boiling, but was lost on charring and dialysis.
(7) St Pancras himself, of whom precious little is known, is buried in Rome, a long way from the charred and soiled remains of the 19th-century slums of Agar Town that were demolished to make way for the Midland Railway's steamy entrance into London.
(8) When the RF probe approached perpendicularly to the cadaver arterial wall, a crater with charring and coagulating necrosis was formed.
(9) The buzz won Charli a deal with Asylum, a subsidiary of major label Atlantic, but she didn't release another thing until 2011.
(10) The percent reductions were 61 in one rabbit fed cholestyramine, 61 and 67 in two rabbits fed 1% Super Char, and 90 in one rabbit fed 2% Super Char.
(11) Wounds in group CS were "sterilized" (0.5-mm spot size, 25 W, CW) by gently heating the wound without causing blanching or charring.
(12) Histologic examination confirmed that this thrombogenicity was associated with greater charring and coagulation necrosis of the media.
(13) Charly Rexach played for Barcelona between 1965 and 1981 and talks about winning the cup, "their cup", as a way of "really pissing [Real Madrid] off."
(14) We investigated the capacity of bone char to remove fluoride from water and its effects on selected bio-indicator organisms.
(15) The charred surface of fish and beef showed strong mutagenic activity in Salmonella typhimurium test strains when activated by S-9 mix of rat liver.
(16) Lased root surfaces revealed craters with a superficial charred layer closely associated with new cementum-like matrix.
(17) The pH of distilled water following contact with bone char rose to 11.5 for white bone-char, 8.3 for grey bone-char, and 7.8 for black bone-char.
(18) Estrogen-binding activity was investigated in liver nuclear and cytosolic preparations of sexually mature female brook char, Salvelinus fontinalis.
(19) Grilled onion salad with pomegranates Serves 4 1kg new season's onions with tops on (or red and spring onions), roots trimmed and washed 1 large pomegranate, or 100g picked pomegranate seeds 1 tbs finely chopped fresh mint For the dressing: 1 large pomegranate, or 100g picked pomegranate seeds 1 small garlic clove, crushed to a paste with salt 6 tbs extra virgin olive oil sea salt and black pepper Place the onions whole over a hot barbecue, directly on the naked flame of a gas hob or under the grill until the skin is charred and crispy all over and the flesh is very soft, for about 15-40 minutes depending on the size of the onions.
(20) Basically, our welfare state has created a beautiful society but we need to keep it that way.” Over a drink in Charly’s, Lone Lincoln Steffensen, the DPP’s regional vice-president, repeats the sentiments of Ragna from Västerås.