(1) [3H]cyclohexyladenosine (CHA) and [3H]PN200-110 were used to label muscarinic and adenosine A1 receptors and L-type calcium channels, respectively.
(2) Since ADO is a metabolic substrate and a nonselective receptor agonist, while CHA is A1-selective and a poor substrate for cellular uptake, neither A2 activation nor cellular uptake altered expression of the A1 effect of exogenous ADO.
(3) R-PIA, CHA and NECA inhibited contraction in both preparations.
(4) In contrast to the relative consistency of the patterns of 3H-CHA binding in these species, 5'-nucleotidase exhibited wide variations in both the absolute amount of activity and its localization.
(5) Concomitant measurement of [3H]-CHA binding in the mesencephalic reticular formation was also carried out in order to explore the neurochemical basis of the development of tolerance.
(6) For aortic relaxation the analogues exhibited the following rank order of potency: NECA greater than adenosine greater than 2-CA greater than R-PIA greater than CHA.
(7) Regulation of c-fos protooncogene activity in rat embryonal fibroblasts (REF), E1Aad5-immortalized REF cells, and E1Aad5 + cHa-ras transformed REF cells has been investigated.
(8) Although more studies are needed, a recent report of potential utilization of nonstimulated oocytes for donor programs as well as IVF-cryopreservation was a promising new development (Cha et al.
(9) 3H-CHA and 3H-NECA binding sites are concentrated in layers 1-3 and upper layer 5 in the visual cortex of adult cats.
(10) In this paper, CDDP-CHA tried to apply for experimental bone and soft tissue sarcoma.
(11) The effect of toxin on adenosine receptors was also evaluated by measuring binding of the adenosine agonist cyclohexyladenosine (CHA).
(12) "All those vuvuzuelas must be interfering with Cha Bum-Kun's ability to remote control his robot creation - er, son - Cha Du-ri," suggests Angela K, a South Korean expat in the US.
(13) The R(-)- and S(+)-enantiomers of N6-(2-phenylisopropyl)adenosine (R-PIA and S-PIA respectively), N6-cyclohexyladenosine (CHA) and 2-chloroadenosine (CADO) caused contractions at low concentrations (0.05-2.0 microM), whereas at higher concentrations, relaxation resulted.
(14) Circular harmonic averaging (CHA), a novel, reference-independent averaging method developed by W. Kunath and H. Sack-Kongehl [1989) Ultramicroscopy 27:171-184) allows analyzing images of single molecules of the receptor in its native membrane-bound state.
(15) An unexpected finding was that R-PIA, 2-CA and CHA all induced contractions at concentrations lower than were required for relaxation, giving a biphasic dose-response curve.
(16) Concentrations to achieve half-maximum responses were 92.5 nM for 2-ClAdo, 39 nM for CHA, and 107 nM for NECA.
(17) Moreover, the addition of guanylyl-5'-imidodiphosphate, a GTP analogue, to the incubation medium reduced CHA binding by the same order of magnitude whether rats were given saline or bicuculline, suggesting that additional adenosine A1 receptors are also functionally linked to G proteins.
(18) Hippocampi from theophylline-treated animals showed a significantly greater number of [3H]CHA binding sites (apparent Bmax; 125% of control, P less than 0.05), without a significant change in binding affinity, and were more sensitive than controls to the inhibitory effects of adenosine on the population spike response.
(19) Both genes were shown to be present in haploid embryos and have been isolated from a genomic library, the exons and deduced amino acid sequences of which are presented here (salmon CHA and CHB).
(20) Accordingly, the peak in adenosine receptor binding, using (-)[125I]iodo-N6-hydroxyphenyl-isopropyladenosine as the radioligand, coincided with CHA-inhibitable adenylate cyclase activity.
Milk
Definition:
(n.) A white fluid secreted by the mammary glands of female mammals for the nourishment of their young, consisting of minute globules of fat suspended in a solution of casein, albumin, milk sugar, and inorganic salts.
(n.) A kind of juice or sap, usually white in color, found in certain plants; latex. See Latex.
(n.) An emulsion made by bruising seeds; as, the milk of almonds, produced by pounding almonds with sugar and water.
(n.) The ripe, undischarged spat of an oyster.
(v. t.) To draw or press milk from the breasts or udder of, by the hand or mouth; to withdraw the milk of.
(v. t.) To draw from the breasts or udder; to extract, as milk; as, to milk wholesome milk from healthy cows.
(v. t.) To draw anything from, as if by milking; to compel to yield profit or advantage; to plunder.
(v. i.) To draw or to yield milk.
Example Sentences:
(1) The absolute recoveries of diazepam, nordazepam and flurazepam in human milk were 84, 86 and 92% and in human plasma 97, 89 and 94%, respectively.
(2) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(3) Phenotypic relationships were examined between final score and 13 type appraisal traits and first lactation milk yield from 2935 Ayrshire, 3154 Brown Swiss, 13,110 Guernsey, 50,422 Jersey, and 924 Milking Shorthorn records.
(4) Four patients with acute brucellosis are described, none of whom had any connexion with farming or milk industry, the source of infection being different in each case.
(5) Milk yield and litter weights were similar but backfat thickness (BF) was greater in 22 C sows (P less than .05) compared to 30 C sows.
(6) In contrast, human breast milk contained substantially increased levels of immunoreactive PTHrP.
(7) Abruptly changing cows from one feeding system to another did not influence milk yield, milk composition, or body weight gain.
(8) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
(9) The presence of BLG in human milk is a common finding in both atopic and non-atopic mothers.
(10) The overall result of this system has been to decrease the coefficients of variation to below 5% for all the milk and serum proteins tested.
(11) The relative effect of the intramammary infections and of different factors related to the cow (parity, stage of lactation, milk yield) on the individual cell counts, were studied for 30 months on the 62 black-and-white Holstein cows of an experimental herd.
(12) Leukocytes were isolated by centrifugation from milk collected at postinjection hour 16.
(13) Postpartum milk samples from 61 heifers and 24 tissues from 2 reactor cattle were culture-negative for B abortus.
(14) The fact that proteolytic activity could be detected within 2 days at 7 degrees C is significant, since bulk cooled milk is normally held for 3 to 4 days at temperatures between 4 and 7 degrees C at farms or factories prior to processing.
(15) Aldi, Lidl and Morrisons are to raise the price they pay their suppliers for milk, bowing to growing pressure from dairy farmers who say the industry is in crisis.
(16) Increasing dietary protein percent raised milk protein percent but not protein yield or yield of other milk components, milk yield, SCM yield, or DM intake.
(17) It was also established that the Y. enterocolitica strains isolated from raw cow milk did not refer to the European serotypes 0:3 and 0:9 that were pathogenic for humans.
(18) The major lipase in human milk is dependent on bile salts for activity and probably participates in intestinal digestion of milk lipids in the newborn.
(19) Calves were fed milk replacer twice daily while housed indoors in wooden-slatted floor box crates (metabolism cages).
(20) During a single reversal trial of two 2-wk experimental periods, teats of all glands of 12 Holstein cows were subjected to a milking routine conducive to large vacuum fluctuations and flooded teat cups.