(n.) A series of links or rings, usually of metal, connected, or fitted into one another, used for various purposes, as of support, of restraint, of ornament, of the exertion and transmission of mechanical power, etc.
(n.) That which confines, fetters, or secures, as a chain; a bond; as, the chains of habit.
(n.) A series of things linked together; or a series of things connected and following each other in succession; as, a chain of mountains; a chain of events or ideas.
(n.) An instrument which consists of links and is used in measuring land.
(n.) Iron links bolted to the side of a vessel to bold the dead-eyes connected with the shrouds; also, the channels.
(n.) The warp threads of a web.
(v. t.) To fasten, bind, or connect with a chain; to fasten or bind securely, as with a chain; as, to chain a bulldog.
(v. t.) To keep in slavery; to enslave.
(v. t.) To unite closely and strongly.
(v. t.) To measure with the chain.
(v. t.) To protect by drawing a chain across, as a harbor.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) In addition, DDT blocked succinate dehydrogenase and the cytochrome b-c span of the electron transport chain, which also secondarily reduced ATP synthesis.
(3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(4) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(5) We have examined overlapping octapeptides from the kappa IIIb light chain variable region and show that some framework peptides have the ability to bind aggregated IgG.
(6) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(7) The lineage and clonality of Hodgkin's disease (HD) were investigated by analyzing the organization of the immunoglobulin and T-cell receptor beta-chain (T beta) gene loci in 18 cases of HD, and for comparison, in a panel of 103 cases of B- and T-cell non-Hodgkin's lymphomas (NHLs) and lymphoid leukemias (LLs).
(8) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(9) Approximately 90% of the patients have a lambda light chain myeloma protein and almost all patients excrete Bence-Jones protein.
(10) The reducing equivalents could be donated by formate or NADH through some segment of the membrane respiratory chain.
(11) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(12) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
(13) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(14) Peptide:N-glycosidase F removed both the asparagine-linked oligosaccharide chains of ricin B-chain in the absence of lactose.
(15) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
(16) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(17) The canine system allows quantitative separation of native heme containing alpha and beta chains which recombine to for tetrameric hemoglobin with normal functional properties (n = 2.17).
(18) The product of this enzymatic hydrolysis was F420 with one less glutamic acid in the side chain.
(19) The present study deals with 832 ossicular chain reconstruction procedures performed in 655 patients from January 1975 to December 1985.
(20) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
Mechanism
Definition:
(n.) The arrangement or relation of the parts of a machine; the parts of a machine, taken collectively; the arrangement or relation of the parts of anything as adapted to produce an effect; as, the mechanism of a watch; the mechanism of a sewing machine; the mechanism of a seed pod.
(n.) Mechanical operation or action.
(n.) An ideal machine; a combination of movable bodies constituting a machine, but considered only with regard to relative movements.
Example Sentences:
(1) Such a signal must be due to a small ferromagnetic crystal formed when the nerve is subjected to pressure, such as that due to mechanical injury.
(2) These data suggest that the hybrid is formed by the same mechanism in the absence and presence of the urea step.
(3) Some common eye movement deficits, and concepts such as 'the neural integrator' and the 'velocity storage mechanism', for which anatomical substrates are still sought, are introduced.
(4) We have investigated the effect of methimazole (MMI) on cell-mediated immunity and ascertained the mechanisms of immunosuppression produced by the drug.
(5) One hour after direct mechanical cardiomassage (DMCM) a moderately pronounced edema of the intercellular spaces in the basal compartment of the seminiferous epithelium, normal content of lactate and succinate dehydrogenases, and a certain decrease in the activity of glucose-6-phosphate dehydrogenases and NAD- and NADP-diaphorases were noted.
(6) It is concluded that amlodipine reduces myocardial ischemic injury by mechanism(s) that may involve a reduction in myocardial oxygen demand as well as by positively influencing transmembrane Ca2+ fluxes during ischemia and reperfusion.
(7) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.
(8) The following is a brief review of the history, mechanism of action, and potential adverse effects of neuromuscular blockers.
(9) However, the mechanism of the inhibitory action is still somewhat uncertain.
(10) It also provides mechanical support for the collateral ligaments during valgus or varus stress of the knee.
(11) We studied the hemodynamic changes caused by bronchoscopy under LA in mechanically ventilated patients and the effect of LA on the endoscopic decline in arterial pO2.
(12) Together these observations suggest that cytotactin is an endogenous cell surface modulatory protein and provide a possible mechanism whereby cytotactin may contribute to pattern formation during development, regeneration, tumorigenesis, and wound healing.
(13) Dilutional studies comparing the mechanism of inhibition of monoamine oxidase produced by Gerovital H3 and by ipronizid demonstrated that Gerovital H3 was a reversible inhibitor of monoamine oxidase.
(14) To investigate the mechanism of enhanced responsiveness of cholesterol-enriched human platelets, we compared stimulation by surface-membrane-receptor (thrombin) and post-receptor (AlF4-) G-protein-directed pathways.
(15) Based on our results, we propose the following hypotheses for the neurochemical mechanisms of motion sickness: (1) the histaminergic neuron system is involved in the signs and symptoms of motion sickness, including vomiting; (2) the acetylcholinergic neuron system is involved in the processes of habituation to motion sickness, including neural store mechanisms; and (3) the catecholaminergic neuron system in the brain stem is not related to the development of motion sickness.
(16) Thus, mechanical restitution of the ventricle is a dynamic process that can be assessed using an elastance-based approach in the in situ heart.
(17) The mechanism by which pertussis toxin (PT) breaks the unresponsiveness of delayed-type hypersensitivity (DTH) to sheep red blood cells (SRBC) was examined in B10 mice.
(18) This suggests that a physiological mechanism exists which can increase the barrier pressure to gastrooesophageal reflux during periods of active secretion of the stomach, as occurs in digestion.
(19) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
(20) Adding a layer of private pensions, it was thought, does not involve Government mechanisms and keeps the money in the private sector.