(n.) A series of links or rings, usually of metal, connected, or fitted into one another, used for various purposes, as of support, of restraint, of ornament, of the exertion and transmission of mechanical power, etc.
(n.) That which confines, fetters, or secures, as a chain; a bond; as, the chains of habit.
(n.) A series of things linked together; or a series of things connected and following each other in succession; as, a chain of mountains; a chain of events or ideas.
(n.) An instrument which consists of links and is used in measuring land.
(n.) Iron links bolted to the side of a vessel to bold the dead-eyes connected with the shrouds; also, the channels.
(n.) The warp threads of a web.
(v. t.) To fasten, bind, or connect with a chain; to fasten or bind securely, as with a chain; as, to chain a bulldog.
(v. t.) To keep in slavery; to enslave.
(v. t.) To unite closely and strongly.
(v. t.) To measure with the chain.
(v. t.) To protect by drawing a chain across, as a harbor.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) In addition, DDT blocked succinate dehydrogenase and the cytochrome b-c span of the electron transport chain, which also secondarily reduced ATP synthesis.
(3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(4) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(5) We have examined overlapping octapeptides from the kappa IIIb light chain variable region and show that some framework peptides have the ability to bind aggregated IgG.
(6) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(7) The lineage and clonality of Hodgkin's disease (HD) were investigated by analyzing the organization of the immunoglobulin and T-cell receptor beta-chain (T beta) gene loci in 18 cases of HD, and for comparison, in a panel of 103 cases of B- and T-cell non-Hodgkin's lymphomas (NHLs) and lymphoid leukemias (LLs).
(8) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(9) Approximately 90% of the patients have a lambda light chain myeloma protein and almost all patients excrete Bence-Jones protein.
(10) The reducing equivalents could be donated by formate or NADH through some segment of the membrane respiratory chain.
(11) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(12) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
(13) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(14) Peptide:N-glycosidase F removed both the asparagine-linked oligosaccharide chains of ricin B-chain in the absence of lactose.
(15) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
(16) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(17) The canine system allows quantitative separation of native heme containing alpha and beta chains which recombine to for tetrameric hemoglobin with normal functional properties (n = 2.17).
(18) The product of this enzymatic hydrolysis was F420 with one less glutamic acid in the side chain.
(19) The present study deals with 832 ossicular chain reconstruction procedures performed in 655 patients from January 1975 to December 1985.
(20) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
Obstruct
Definition:
(v. t.) To block up; to stop up or close, as a way or passage; to place an obstacle in, or fill with obstacles or impediments that prevent or hinder passing; as, to obstruct a street; to obstruct the channels of the body.
(v. t.) To be, or come, in the way of; to hinder from passing; to stop; to impede; to retard; as, the bar in the harbor obstructs the passage of ships; clouds obstruct the light of the sun; unwise rules obstruct legislation.
Example Sentences:
(1) We have previously shown that intratracheally instilled silica (quartz) produces both morphologic evidence of emphysema and small-airway changes, and functional evidence of airflow obstruction.
(2) Evaluation revealed tricuspid insufficiency, a massively dilated right internal jugular vein, and obstruction of the left internal jugular vein.
(3) A segment of vas deferens was transplanted to the contralateral deferens with the intention of improving treatment for certain cases of infertility caused by obstruction.
(4) In the case presented, overdistension of a jejunostomy catheter balloon led to intestinal obstruction and pressure necrosis (of the small bowel), with subsequent abscess formation leading to death from septicemia.
(5) During the procedure, acute respiratory failure developed as a result of tracheal obstruction.
(6) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
(7) Delineation of the presence and anatomy of an obstructed, nonfunctioning upper-pole duplex system often requires multiple imaging techniques.
(8) Therefore, the measurement of the alpha-antitrypsin content plays the crucial part in differential diagnosis of primary (hereditary determined) and secondary (obstructive) emphysema.
(9) In 2 patients who had received cadaveric renal allograft, ureteral obstruction was detected six and one-half and five and one-half years after transplantation.
(10) Two cases are presented of bilateral ureteral obstruction and uremia due to pressure from nodes involved in disseminated lymphoma.
(11) The occurrence of episodes of desaturation during sleep in patients suffering from chronic airflow obstruction is well known.
(12) Keep it in the ground campaign Though they draw on completely different archives, leaked documents, and interviews with ex-employees, they reach the same damning conclusion: Exxon knew all that there was to know about climate change decades ago, and instead of alerting the rest of us denied the science and obstructed the politics of global warming.
(13) Tubal obstruction could be demonstrated in only one of these patients.
(14) Schistosomal obstructive uropathy was studied by clinical, laboratory epidemiologic and pathologic analysis in 155 Egyptian patients treated surgically.
(15) For obstruction of greater than or equal to 50% of the pulmonary vascular cross-sectional area and pulmonary hypertension thrombolytic therapy should be given and insertion of an inferior caval filter can be considered.
(16) Regression of the tumor occurred during an episode of mechanical small bowel obstruction.
(17) Comparison with 99Tc-pyrophosphate uptake in infarcted dog heart, induced by selective obstruction of a coronary artery, suggest that the 111In-labelled F(ab')2 localizes specifically in infarcted myocardium only.
(18) In case of biliary and pancreatic duct obstruction with pure pancreatic reflux, both oedema and inflammatory infiltrations were evident, whereas, in the presence of biliary reflux too, more serious histological features were detected.
(19) We recently treated a patient in whom HPVG was caused by intestinal pseudo-obstruction.
(20) In patients with acute exacerbations of chronic obstructive pulmonary disease, although either sympathomimetic or anticholinergic therapy provides bronchodilatation, no further benefit could be demonstrated from combination therapy.