(n.) A series of links or rings, usually of metal, connected, or fitted into one another, used for various purposes, as of support, of restraint, of ornament, of the exertion and transmission of mechanical power, etc.
(n.) That which confines, fetters, or secures, as a chain; a bond; as, the chains of habit.
(n.) A series of things linked together; or a series of things connected and following each other in succession; as, a chain of mountains; a chain of events or ideas.
(n.) An instrument which consists of links and is used in measuring land.
(n.) Iron links bolted to the side of a vessel to bold the dead-eyes connected with the shrouds; also, the channels.
(n.) The warp threads of a web.
(v. t.) To fasten, bind, or connect with a chain; to fasten or bind securely, as with a chain; as, to chain a bulldog.
(v. t.) To keep in slavery; to enslave.
(v. t.) To unite closely and strongly.
(v. t.) To measure with the chain.
(v. t.) To protect by drawing a chain across, as a harbor.
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) In addition, DDT blocked succinate dehydrogenase and the cytochrome b-c span of the electron transport chain, which also secondarily reduced ATP synthesis.
(3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(4) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(5) We have examined overlapping octapeptides from the kappa IIIb light chain variable region and show that some framework peptides have the ability to bind aggregated IgG.
(6) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(7) The lineage and clonality of Hodgkin's disease (HD) were investigated by analyzing the organization of the immunoglobulin and T-cell receptor beta-chain (T beta) gene loci in 18 cases of HD, and for comparison, in a panel of 103 cases of B- and T-cell non-Hodgkin's lymphomas (NHLs) and lymphoid leukemias (LLs).
(8) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(9) Approximately 90% of the patients have a lambda light chain myeloma protein and almost all patients excrete Bence-Jones protein.
(10) The reducing equivalents could be donated by formate or NADH through some segment of the membrane respiratory chain.
(11) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(12) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
(13) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(14) Peptide:N-glycosidase F removed both the asparagine-linked oligosaccharide chains of ricin B-chain in the absence of lactose.
(15) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
(16) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(17) The canine system allows quantitative separation of native heme containing alpha and beta chains which recombine to for tetrameric hemoglobin with normal functional properties (n = 2.17).
(18) The product of this enzymatic hydrolysis was F420 with one less glutamic acid in the side chain.
(19) The present study deals with 832 ossicular chain reconstruction procedures performed in 655 patients from January 1975 to December 1985.
(20) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
Wild
Definition:
(superl.) Living in a state of nature; inhabiting natural haunts, as the forest or open field; not familiar with, or not easily approached by, man; not tamed or domesticated; as, a wild boar; a wild ox; a wild cat.
(superl.) Growing or produced without culture; growing or prepared without the aid and care of man; native; not cultivated; brought forth by unassisted nature or by animals not domesticated; as, wild parsnip, wild camomile, wild strawberry, wild honey.
(superl.) Desert; not inhabited or cultivated; as, wild land.
(superl.) Savage; uncivilized; not refined by culture; ferocious; rude; as, wild natives of Africa or America.
(superl.) Not submitted to restraint, training, or regulation; turbulent; tempestuous; violent; ungoverned; licentious; inordinate; disorderly; irregular; fanciful; imaginary; visionary; crazy.
(superl.) Exposed to the wind and sea; unsheltered; as, a wild roadstead.
(superl.) Indicating strong emotion, intense excitement, or /ewilderment; as, a wild look.
(superl.) Hard to steer; -- said of a vessel.
(n.) An uninhabited and uncultivated tract or region; a forest or desert; a wilderness; a waste; as, the wilds of America; the wilds of Africa.
(adv.) Wildly; as, to talk wild.
Example Sentences:
(1) In contrast, resting cells of strain CHA750 produced five times less IAA in a buffer (pH 6.0) containing 1 mM-L-tryptophan than did resting cells of the wild-type, illustrating the major contribution of TSO to IAA synthesis under these conditions.
(2) Comparison of wild type and the mutant parD promoter sequences indicated that three short repeats are likely involved in the negative regulation of this promoter.
(3) Insensitive variants die more slowly than wild type cells, with 10-20% cell death observed within 24 h after addition of dexamethasone.
(4) But when he speaks, the crowds who have come together to make a stand against government corruption and soaring fuel prices cheer wildly.
(5) RNAs encoding a wild-type (RBK1) and a mutant (RBK1(Y379V,V381T); RBK1*) subunit of voltage-dependent potassium channels were injected into Xenopus oocytes.
(6) One rat strain (TAS) is susceptible to the anticoagulant and lethal effects of warfarin and the other two strains are homozygous for warfarin resistance genes from either wild Welsh (HW) or Scottish (HS) rats.
(7) No reversions to wild-type levels were observed in 555 heterozygous offspring of crosses between homozygous Campines and normals.
(8) The kinetics of endocytosis and recycling of the wild-type and mutant receptors were compared.
(9) Genetic regulation of the ilvGMEDA cluster involves attenuation, internal promoters, internal Rho-dependent termination sites, a site of polarity in the ilvG pseudogene of the wild-type organism, and autoregulation by the ilvA gene product, the biosynthetic L-threonine deaminase.
(10) In contrast, strains carrying the substitutions Ile-30----Phe, Gly-33----Leu, Gly-58----Leu, and Lys-34----Val and the Lys-34----Val, Glu-37----Gln double substitution were found to possess a coupled phenotype similar to that of the wild type.
(11) With one exception, the mutant control regions showed elevated beta-lactamase activity in comparison to the wild-type.
(12) Intercistronic complementation of these mutants with pm1493 and dl121, two SV40 mutants that are defective in agnoprotein but encode wild-type T antigen, results in an increased synthesis of agnoprotein in the infected cells.
(13) For example, stem pairing with a sequence other than wild-type resulted in normal protein binding in vitro but derepression of protein synthesis in vivo.
(14) Phage lysates of wild-type cells are capable of transducing auxotrophs of strain 78 to prototrophy at frequencies ranging from 0.3 x 10(-7) to 34 x 10(-7) per plaque-forming unit adsorbed.
(15) The mutant spores are pleomorphic and differ both in shape and size from the wild-type spores.
(16) Addition of streptomycin restores much of the wild-type behaviour.
(17) She read geography at Oxford, where Benazir Bhutto (a future prime minister of Pakistan, assassinated in 2007) introduced May to her future husband, Philip May: "I hate to say this, but it was at an Oxford University Conservative Association disco… this is wild stuff.
(18) A plasmid carrying this mutation, along with wild-type genes encoding the c and b subunits, was unusual in that it failed to complement a chromosomal c-subunit mutation on succinate minimal medium.
(19) Using allozymes as the genetic probe, data are presented which show that wild Drosophila buzzatii females and males engaged in copulation mate at random.
(20) Intact wild-type cells, or those of a mutant in which the core region of the lipopolysaccharide was absent, were equally resistant to pronase treatment.