What's the difference between chained and shackled?
Chained
Definition:
(imp. p. p.) of Chain
Example Sentences:
(1) We used the polymerase chain reaction (PCR) to amplify the breakpoint area of alpha-thalassemia-1 of Southeast Asia type and several parts of the alpha-globin gene cluster to make a differential diagnosis between alpha-thalassemia-1 and Hb Bart's hydrops fetalis.
(2) In addition, DDT blocked succinate dehydrogenase and the cytochrome b-c span of the electron transport chain, which also secondarily reduced ATP synthesis.
(3) The high transition enthalpy for kerasin is ascribed to a lesser accommodation of gauche conformers in the hydrocarbon chains just below the transition temperature.
(4) Mannose receptor mediated uptake by the reticuloendothelial system has been suggested as an explanation for the rapid removal of ricin A chain antibody conjugates from the circulation after their administration.
(5) We have examined overlapping octapeptides from the kappa IIIb light chain variable region and show that some framework peptides have the ability to bind aggregated IgG.
(6) The Tyr side chain had two conformations of comparable energy, one over the ring between the Gln and Asn side chains, and the other with the Tyr side chain away from the ring.
(7) The lineage and clonality of Hodgkin's disease (HD) were investigated by analyzing the organization of the immunoglobulin and T-cell receptor beta-chain (T beta) gene loci in 18 cases of HD, and for comparison, in a panel of 103 cases of B- and T-cell non-Hodgkin's lymphomas (NHLs) and lymphoid leukemias (LLs).
(8) Only those derivatives with a free amino group and net positive charge in the side chain were effective.
(9) Approximately 90% of the patients have a lambda light chain myeloma protein and almost all patients excrete Bence-Jones protein.
(10) The reducing equivalents could be donated by formate or NADH through some segment of the membrane respiratory chain.
(11) Thus there may be four types of LPS in PACI: one contains unsubstituted core polysaccharide and yields L2 on acid hydrolysis, another has short antigenic side-chains of the SR type and yields the LI fraction, while the two high molecular weight fractions are derived from core polysaccharides with different side-chains.
(12) The seve polypeptide chains investigated had generalyy similar properties; all contained two residues per molecule of tryptophan and N-acetylserine was the common N-terminal amino acid residue.
(13) Urine specimens from patient REE also contained a light chain fragment that lacked the first (amino-terminal) 85 residues of the native light chain but otherwise was identical in sequence to the light chain REE.
(14) Peptide:N-glycosidase F removed both the asparagine-linked oligosaccharide chains of ricin B-chain in the absence of lactose.
(15) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
(16) In general, optimal DAGAT activity in vitro was observed when long-chain unsaturated acyl-CoAs and diacylglycerols (DAGs) containing long acyl chains were used as substrates for in vitro TAG synthesis (although 1,2-didecanoin was also very effective).
(17) The canine system allows quantitative separation of native heme containing alpha and beta chains which recombine to for tetrameric hemoglobin with normal functional properties (n = 2.17).
(18) The product of this enzymatic hydrolysis was F420 with one less glutamic acid in the side chain.
(19) The present study deals with 832 ossicular chain reconstruction procedures performed in 655 patients from January 1975 to December 1985.
(20) On the other hand, if we correct for the population of HMM with degraded light chain 2, the difference in the binding constants in the presence and absence of Ca2+ may be as great as 5-fold.
Shackled
Definition:
(imp. & p. p.) of Shackle
Example Sentences:
(1) They will demand that the shackles be taken off local authorities so they can tackle a homelessness crisis.
(2) Shackles were found in the cellar, and yesterday police found a trap door.
(3) Shackling and ‘a full strip search’ On the morning of 21 October 2013, LaTonia Wilson was pulling out of her mechanic’s garage with her husband, Atheris Mann; her eldest son, Jessie Patrick; and their two-year-old son Marquise.
(4) How Chicago police used pot to disappear young people at Homan Square Read more Davis, a Democrat who represents the neighborhood that includes the Homan Square site, had until Wednesday only said publicly that he would “strongly support” a federal inquiry into what 11 detainees – in strikingly similar detailed accounts provided to the Guardian – have described as extended interrogation without access to legal counsel or their families, often while shackled.
(5) On this evidence, the shackles, in place ever since that World Cup in France, finally appear to be off.
(6) It is modern slavery enforced not through shackles and whips, but by fiddled contracts, missing permits and paperwork and the Guardian has found it happening just down the road from the desert palace of Qatar’s emir, Sheikh Tamim bin Khalifa al-Thani.
(7) Mané, in particular, has become erratic, while Tadic has suffered from the fact that opponents have studied him after his sparkling start to the campaign and increased their efforts to shackle him, partially by curtailing the ability of Southampton’s flying full-backs to support him down the flanks.
(8) Military policy Victory on Sunday will boost attempts by Abe and his fellow conservatives to further loosen the political shackles on Japan’s self-defence forces – actually a highly trained, well-equipped army, navy and air force.
(9) The NHS has experienced numerous attempts to free staff from the shackles of unnecessary paperwork to allow more time for patient care.
(10) The blindfold, shackles, threats and beatings were just the white noise of his ordeal, he says.
(11) Second, its shackled to historicism, constantly looking to the past.
(12) We face the prospect of a week of party manifestos full of reckless promises unbelieved by electors yet shackling future chancellors.
(13) It is so nice that the shackles have been taken off me and I can now fight for America the way I want to,” he tweeted .
(14) I would love to see the selection criteria for that job.’” Facebook Twitter Pinterest From a blindfolded boat ride to threats against his family members and hours shackled to Gitmo floors, Zuley’s interrogation of Mohamedou Ould Slahi shocked investigators.
(15) "He was not only able to break the shackles of bigotry and bias and hate, but he did it without internalising the battles he was fighting."
(16) In March, Gambian president Yahya Jammeh announced plans to throw off the shackles of the colonial past by discontinuing the use of English as an official language .
(17) Sir Edward Leigh, a former minister, said breaking up the coalition would be one way of showing fed-up Conservative voters that Cameron was serious about addressing their concerns, instead of being shackled to the Liberal Democrats .
(18) But even allowing for that fact, and the long-known departure of Lampard, this will undoubtedly be a summer of upheaval for last season’s champions, not least with Uefa looking increasingly likely to loosen the shackles of financial fair play.
(19) Not only are their pay and rations fixed centrally but their revenue is shackled.
(20) When she fled the violence of Honduras and settled with relatives in Atlanta, Gutiérrez, 31, met regularly with immigration officials and wore an electronic ankle shackle, so they could track her.