(n.) A soft, earthy substance, of a white, grayish, or yellowish white color, consisting of calcium carbonate, and having the same composition as common limestone.
(n.) Finely prepared chalk, used as a drawing implement; also, by extension, a compound, as of clay and black lead, or the like, used in the same manner. See Crayon.
(v. t.) To rub or mark with chalk.
(v. t.) To manure with chalk, as land.
(v. t.) To make white, as with chalk; to make pale; to bleach.
Example Sentences:
(1) The young screenwriters possibly needed to have chalked up a few miles before they could deliver really workable scripts."
(2) The blue skipping rope – that’s the key to this race.” My eight-year-old daughter looked at me like I was mad … but when it came time for the year 3 skipping race, she did as she was told – and duly chalked up a glorious personal best in third place.
(3) His flicked header into the net seconds later, chalked off by an offside flag, confirmed the forward's luck was not in.
(4) Inside the first 10 minutes, Boyd hit the bar and Lukas Jutkiewicz saw a goal correctly chalked off for offside, while Danny Ings headed just wide at 2-1, and substitute Ashley Barnes struck the bar late on.
(5) France chalked up growth of 0.5%, beating economists' expectations, the best growth figures Fran ç ois Hollande has seen since he was elected president 15 months ago.
(6) 2) If the board and adjacent ones are firmly fixed, dust talc or chalk through the cracks to stop them rubbing together.
(7) The phrase chalk and cheese springs to mind, or as the French say jour et nuit – day and night.
(8) Remember the Theater People: the gal rigging lights for her community theater's production of The Chalk Garden in Brainerd, Minnesota.
(9) The house was later covered in chalk and finally became a curious white landmark.
(10) It is recommended that overall average and chalk carving be given equal emphasis in the selection process.
(11) HS2’s barrister, James Strachan QC, was listening closely, however, and addressed specific points with a lawyer’s care to make no rash promises: HS2’s noise would be less than traffic on the A413; HS2 were working with the RSPB to “mitigate” for barn owls; and, “If there’s a need for chalk grassland, that’s the sort of thing that can be put into these areas to compensate.” Wendy Gray was allowed to respond: “It’s very difficult to be reassured on an unknown quantity,” she said.
(12) According to the sonographic pattern and to the scintigraphic imaging the focal lesions were analysed as micro- or macrofollicular adenomas, autonomous adenomas, cysts and chalk.
(13) Shortly after arriving in Rome, Las Vegas and Tallinn, however, the lines of gameless resolve I had chalked across my mind were wiped clean.
(14) The economy is forecast to chalk up only 0.75% growth this year, and to contract by 1% in 2009 - which would be the first full year of contraction since 1991.
(15) Look, Newsnight is made by 13-year-olds,” he said, speaking at the Chalke Valley history festival about his new book on the first world war.
(16) A series of 75 spoilt soft lenses with opacities (mostly manifesting as discrete spots or as large areas of cloudiness, chalk-white in appearance) were subjected to histochemical, electron microscopical, electron probe x-ray microanalytical, x-ray diffraction, atomic absorption spectro-photometric, and biochemical analyses.
(17) A suspension of chalk powder was injected into the cavity of the urinary bladder of Fischer 344 rats.
(18) The reactivity of soils varies widely as geological and sedimentological conditions offer typical but different environments: gravels, chalk soil, clay, salt soils, sands, cave earths are examples of this wide variety, including atmospheric and biogenetic implications.
(19) A staircase descends steeply into a network of tunnels and cellars that lead to extraordinary old chalk pits.
(20) Photograph: Graham Turner for the Guardian But to date, the prospect of building on abandoned north Kent chalk quarries, has been so unattractive to housebuilders that they have delivered homes at the rate of just 25 a year when 1,000 a year are needed.
Malm
Definition:
(n.) Alt. of Malmbrick
Example Sentences:
(1) This substance stopped fetal and skin (MALME 3 line) fibroblast propagation.
(2) In maxicells, the resulting plasmid permitted tac12-promoted synthesis of two polypeptides, encoded by gene malM, with apparent molecular weights of 37 X 10(3) and 34.5 X 10(3).
(3) Smaller increases were noted with the cell lines RPMI 7951, HT 144, Malme-3M, MEL-2, and no significant increase was observed with MEL-5.
(4) Treatment of MALME-3 cells with BESPM resulted in an accumulation of N-acetylspermidine in cells and the enhanced excretion of putrescine, spermidine, and N-acetylspermidine into the medium.
(5) The malM gene, encoding a periplasmic protein of unknown function in Escherichia coli, is a highly conserved as genes encoding proteins of known function from the same region.
(6) Treatment of human MALME-3 melanoma cells with 10 microM N1,N11-bis(ethyl)norspermine (BENSPM) for 48-72 h increased SSAT activity by some 1000- to 4000-fold and enabled purification of the enzyme by established procedures--binding on immobilized spermine and elution with spermine followed by binding on Matrex Blue A and elution with coenzyme A.
(7) One malM mutation corresponding to an A.T----G.C transition showed a 10-fold-higher spontaneous reversion frequency than other such transitions in a wild-type background.
(8) From 1981, we changed a surgical procedure fro Gersony-Malm procedure to the posterior approach method, and a surgical technique from the deep hypothermia and the circulatory arrest to the moderate hypothermia and the pump perfusion.
(9) The patient was treated with repair using Gersony-Malm's method and plasty of SVC because of the stenosis of the common pulmonary vein's entrance to the SVC.
(10) In MALME-3 cells, SSAT accumulation was found to be differentially modulated by the BESPM homologues, N1,N11-bis-(ethyl)norspermine and N1,N14-bis-(ethyl)homospermine, which were 5-fold more and 9-fold less effective, respectively, than BESPM in increasing SSAT but similar in analogue uptake and effects on polyamine biosynthesis and cell growth inhibition.
(11) The intergenic region between lamB and the following gene, malM, comprises conserved segments, including one palindromic unit.
(12) They result in an increase in amount and specific activity of a MalM-LacZ hybrid protein.
(13) The complete malM open reading frame was cloned under control of the tac 12 promoter.
(14) Mutations affecting the hydrophobic core of the N-terminal extension of the MalM protein have been isolated.
(15) The calcium balance studies of Malm were re-analysed to quantify the seasonal variation he had demonstrated in one group of men.
(16) We show that the chromosomal malM gene is expressed as part of the malK-lamB operon, and that its product is periplasmic.
(17) Antiproliferative effects ranged from slowing of cell growth in the less SSAT responsive lines (LOX, SH-1) to total cessation of cell growth or overt cytotoxicity in the more potently SSAT responsive lines (MALME-3, Ebey).
(18) Finally, we demonstrate with nuclease S1 mapping experiments that the mRNA terminates at a typical rho-independent terminator located about 45 base-pairs beyond the end of gene malM, which is thus the last gene of the malK-lamB operon.
(19) We have subcloned and sequenced the genes malF and malM of Salmonella typhimurium, thereby completing the determination of the nucleotide sequence of its 'maltose B' regulon.
(20) They failed to kill autologous B cells, erythroid progenitors present in allogeneic bone marrow, and a number of cultured human tumor cells (Malme, CAKI) even after prolonged (36 h) co-culture.