What's the difference between challenged and new?

Challenged


Definition:

  • (imp. & p. p.) of Challenge

Example Sentences:

  • (1) Bronchial challenge caused an immediate asthmatic response.
  • (2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
  • (3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
  • (4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
  • (5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
  • (6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
  • (7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
  • (8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
  • (9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
  • (10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
  • (11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
  • (12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
  • (13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
  • (14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
  • (15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
  • (16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
  • (17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
  • (18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
  • (19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
  • (20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.

New


Definition:

  • (superl.) Having existed, or having been made, but a short time; having originated or occured lately; having recently come into existence, or into one's possession; not early or long in being; of late origin; recent; fresh; modern; -- opposed to old, as, a new coat; a new house; a new book; a new fashion.
  • (superl.) Not before seen or known, although existing before; lately manifested; recently discovered; as, a new metal; a new planet; new scenes.
  • (superl.) Newly beginning or recurring; starting anew; now commencing; different from has been; as, a new year; a new course or direction.
  • (superl.) As if lately begun or made; having the state or quality of original freshness; also, changed for the better; renovated; unworn; untried; unspent; as, rest and travel made him a new man.
  • (superl.) Not of ancient extraction, or of a family of ancient descent; not previously kniwn or famous.
  • (superl.) Not habituated; not familiar; unaccustomed.
  • (superl.) Fresh from anything; newly come.
  • (adv.) Newly; recently.
  • (v. t. & i.) To make new; to renew.

Example Sentences:

  • (1) The liver metastasis was produced by intrasplenic injection of the fluid containing of KATOIII in nude mouse and new cell line was established using the cells of metastatic site.
  • (2) The femoral component, made of Tivanium with titanium mesh attached to it by a new process called diffusion bonding, retains superalloy fatigue strength characteristics.
  • (3) Apparently, the irradiation with visible light of a low intensity creates an additional proton gradient and thus stimulates a new replication and division cycle in the population of cells whose membranes do not have delta pH necessary for the initiation of these processes.
  • (4) If ascorbic acid was omitted from the culture medium, the extensive new connective tissue matrix was not produced.
  • (5) Neuropsychological testing is a relatively new field in the area of clinical neuroscience.
  • (6) says Gregg Wallace opening the new series of Celebrity MasterChef (Mon-Fri, 2.15pm, BBC1).
  • (7) A new balloon catheter has been developed for angioplasty.
  • (8) A new and simple method of serotyping campylobacters has been developed which utilises co-agglutination to detect the presence of heat-stable antigens.
  • (9) These results suggest the presence of a new antigen-antibody system for another human type C retrovirus related antigens(s) and a participation of retrovirus in autoimmune diseases.
  • (10) The combined analysis of pathogenesis and genetics associated with the salmonella virulence plasmids may identify new systems of bacterial virulence and the genetic basis for this virulence.
  • (11) The previous year, he claimed £1,415 for two new sofas, made two separate claims of £230 and £108 for new bed linen, charged £86 for a new kettle and kitchen utensils and made two separate claims, of £65 and £186, for replacement glasses and crockery.
  • (12) Richard Bull Woodbridge, Suffolk • Why does Britain need Chinese money to build a new atomic generator ( Letters , 20 October)?
  • (13) This new observation offers good possibilities to study the metabolism of tryptophan at the cellular level.
  • (14) Graft life is even more prolonged with patch angioplasty at venous outflow stenoses or by adding a new segment of PTFE to bypass areas of venous stenosis.
  • (15) Paradoxically, each tax holiday increases the need for the next, because companies start holding ever greater amounts of their tax offshore in the expectation that the next Republican government will announce a new one.
  • (16) Michael Schumacher’s manager hopes F1 champion ‘will be here again one day’ Read more Last year, Red Bull were frustrated by Mercedes, Ferrari and Honda as they desperately looked for a new engine supplier.
  • (17) The strongest predictor of non-sudden cardiac death was the New York Heart Association functional class.
  • (18) But RWE admitted it had often only been able to retain customers with expired contracts by offering them new deals with more favourable conditions.
  • (19) In the fall of 1975, 1,915 children in grades K through eight began a school-based program of supervised weekly rinsing with 0.2 percent aqueous solution of sodium fluoride in an unfluoridated community in the Finger Lakes area of upstate New York.
  • (20) Schneiderlin, valued at an improbable £27m, and the currently injured Jay Rodriguez are wanted by their former manager Mauricio Pochettino at Spurs, but the chairman Ralph Krueger has apparently called a halt to any more outgoings, saying: “They are part of the core that we have decided to keep at Southampton.” He added: “Jay Rodriguez and Morgan Schneiderlin are not for sale and they will be a part of our club as we enter the new season.” The new manager Ronald Koeman has begun rebuilding by bringing in Dusan Tadic and Graziano Pellè from the Dutch league and Krueger said: “We will have players coming in, we will make transfers to strengthen the squad.