What's the difference between challenging and determine?

Challenging


Definition:

  • (p. pr. & vb. n.) of Challenge

Example Sentences:

  • (1) Bronchial challenge caused an immediate asthmatic response.
  • (2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
  • (3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
  • (4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
  • (5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
  • (6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
  • (7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
  • (8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
  • (9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
  • (10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
  • (11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
  • (12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
  • (13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
  • (14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
  • (15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
  • (16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
  • (17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
  • (18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
  • (19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
  • (20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.

Determine


Definition:

  • (v. t.) To fix the boundaries of; to mark off and separate.
  • (v. t.) To set bounds to; to fix the determination of; to limit; to bound; to bring to an end; to finish.
  • (v. t.) To fix the form or character of; to shape; to prescribe imperatively; to regulate; to settle.
  • (v. t.) To fix the course of; to impel and direct; -- with a remoter object preceded by to; as, another's will determined me to this course.
  • (v. t.) To ascertain definitely; to find out the specific character or name of; to assign to its true place in a system; as, to determine an unknown or a newly discovered plant or its name.
  • (v. t.) To bring to a conclusion, as a question or controversy; to settle authoritative or judicial sentence; to decide; as, the court has determined the cause.
  • (v. t.) To resolve on; to have a fixed intention of; also, to cause to come to a conclusion or decision; to lead; as, this determined him to go immediately.
  • (v. t.) To define or limit by adding a differentia.
  • (v. t.) To ascertain the presence, quantity, or amount of; as, to determine the parallax; to determine the salt in sea water.
  • (v. i.) To come to an end; to end; to terminate.
  • (v. i.) To come to a decision; to decide; to resolve; -- often with on.

Example Sentences:

  • (1) This study was undertaken to determine whether the survival of Hispanic patients with squamous cell carcinoma of the head and neck was different from that of Anglo-American patients.
  • (2) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
  • (3) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
  • (4) The prenatal risk determined by smoking pregnant woman was studied by a fetal electrocardiogram at different gestational ages.
  • (5) These results indicated that the PG determination was the most accurate predictor of fetal lung well-being prior to birth among the clinical tests so far reported.
  • (6) The nucleotide sequence of a 2.2-kb DNA fragment which contains the complete RAD7 gene was determined.
  • (7) We have determined the genomic structure of the fosB gene and shown that it consists of 4 exons and 3 introns at positions also found in the c-fos gene.
  • (8) We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
  • (9) It is quite interesting to analyse which gene of the virus determines the characteristics of the virus.
  • (10) Spectrophotometric determination of the sulfhydryl content in the animal tissue before (control) and after using 6,6'-Dithiodinicotinic acid is applied.
  • (11) We determined whether serological investigations can assist to distinguish between chronic idiopathic autoimmune thrombocytopenia (cAITP) and immune-mediated thrombocytopenia in patients at risk to develop systemic lupus erythematosus (SLE); 82 patients were seen in this institution for the evaluation of immune thrombocytopenia.
  • (12) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
  • (13) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
  • (14) Complementarity determining regions (CDR) are conserved to different extents, with the first CDR region in all family members being among the most conserved segments of the molecule.
  • (15) Acquired drug resistance to INH, RMP, and EMB can be demonstrated in M. kansasii, and SMX in combination with other agents chosen on the basis of MIC determinations are effective in the treatment of disease caused by RMP-resistant M. kansasii.
  • (16) In animal experiments pharmacological properties of the low molecular weight heparin derivative CY 216 were determined.
  • (17) Using the oocyte system to express size-fractionated mRNA, we have also determined that the mRNA coding for this protein is between 1.9-2.4 kilobases in length.
  • (18) Despite of the increasing diagnostic importance of the direct determination of the parathormone which is at first available only in special institutions in these cases methodical problems play a less important part than the still not infrequent appearing misunderstanding of the adequate basic disease.
  • (19) The procedure used in our laboratory was not able to provide accurate determination of the concentrations of these binding forms.
  • (20) The serum concentration of hyaluronan (HYA) was determined in 59 patients with various myeloproliferative disorders, including 33 patients with idiopathic myelofibrosis.