What's the difference between challenging and inflammatory?

Challenging


Definition:

  • (p. pr. & vb. n.) of Challenge

Example Sentences:

  • (1) Bronchial challenge caused an immediate asthmatic response.
  • (2) When chimeric animals were subjected to a lethal challenge of endotoxin, their response was markedly altered by the transferred lymphoid cells.
  • (3) This frees the student to experience the excitement and challenge of learning and the joy of helping people.
  • (4) The degree of increase in Meth responsiveness elicited by the initial provocation is a major factor in determining the airway response to a subsequent HS challenge.
  • (5) Intranasal challenge of allergic subjects with the allergen to which they are sensitive rapidly produces sneezing, rhinorrhea, and airway obstruction.
  • (6) Matthias Müller, VW’s chief executive, said: “In light of the wide range of challenges we are currently facing, we are satisfied overall with the start we have made to what will undoubtedly be a demanding fiscal year 2016.
  • (7) In 1935, Einstein challenged the prevailing interpretation of quantum theory.
  • (8) A shrinking populace is perhaps a greater challenge than any problems with Russia.
  • (9) Intraperitoneal injection of indomethacin to pretreated animals resulted in increased levels of IL-1 and TNF and decreased levels of PGE2 following challenge with E. coli.
  • (10) Think of Nelson Mandela – there is a determination, an unwillingness to bend in the face of challenges, that earns you respect and makes people look to you for guidance.
  • (11) The children's pulse, pulse rate variability, and blood pressure were then measured at rest and during a challenging situation.
  • (12) At first it looked as though the winger might have shown too much of the ball to the defence, yet he managed to gain a crucial last touch to nudge it past Phil Jones and into the path of Jerome, who slipped Chris Smalling’s attempt at a covering tackle and held off Michael Carrick’s challenge to place a shot past an exposed De Gea.
  • (13) The results support the notion that mediator lymphocytes circulate in tumor immunized rats in a noncytotoxic state, specifically recognize tumor cells at a challenge site, and mediate induction of effector cells locally.
  • (14) The role of blood acetylcholinesterase in moderating the effects of organophosphate challenge in rats was tested.
  • (15) In the first trial to investigate the effect of tick control, significant improvements in liveweight gain (LWG) occurred only in periods of medium to high challenge with adult Amblyomma variegatum.
  • (16) The SNT and the I-ELISA indicated that the pigs responded to vaccination and challenge.
  • (17) When caffeine evokes a contraction, and only then, crayfish muscle fibers become refractory to a second challenge with caffeine for up to 20 min in the standard saline (5 mM K(o)).
  • (18) This observation seriously challenges the hypothesis that SCE cancellation results as a consequence of persistence of the lesions induced by these agents.
  • (19) Injection of about four ImD 50 of vaccine intracerebrally produced a local immunity, resulting in an immediate kill of challenge organisms given 14 days later.
  • (20) There was no correlation between anti-TNP-precipitating antibody titer after sensitization and the ability to respond to challenge by hapten-heterologous carrier.

Inflammatory


Definition:

  • (a.) Tending to inflame, kindle, or irritate.
  • (a.) Tending to excite anger, animosity, tumult, or sedition; seditious; as, inflammatory libels, writings, speeches, or publications.
  • (a.) Accompanied with, or tending to cause, preternatural heat and excitement of arterial action; as, an inflammatory disease.

Example Sentences:

  • (1) The data indicate that ebselen is likely to be useful in the therapy of inflammatory conditions in which reactive oxygen species, such as peroxides, play an aetiological role.
  • (2) In all cases the polyarthritis is cured by anti-inflammatory treatment in 1-6 months.
  • (3) Exudative inflammatory processes predominate in the ulcer floor.
  • (4) An inflammatory process than occurs in the airways that is characterized by an influx of eosinophils and neutrophils into the airway epithelium and bronchial fluids.
  • (5) Diseases of the gastric musculature, including the inflammatory and endocrine myopathies, muscular dystrophies, and infiltrative disorders, can result in significant gastroparesis.
  • (6) We measured soluble CD8 (sCD8) levels in the CSF of patients with MS, other inflammatory neurologic diseases (INDs), and noninflammatory neurologic diseases (NINDs).
  • (7) To investigate the relationship between Helicobacter pylori infection and nonsteroidal anti-inflammatory drug (NSAID) intolerance and the effect of gold use on the seroprevalence of H. pylori.
  • (8) These same molecules may be equally responsible for the pathologic characteristics of the immune response seen, for example, in inflammatory bowel diseases.
  • (9) The typical appearance of inflammatory and bullous diseases may be changed when they occur on the vulva.
  • (10) Thus, human bronchial epithelial cells can express the IL-8 gene, with expression in response to the inflammatory mediator TNF regulated mainly at the transcriptional level, and with elements within the 5'-flanking region of the gene that are directly or indirectly modulated by the TNF signal.
  • (11) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
  • (12) In particular, inflammatory reaction was significantly more frequent and severe in ischemic groups than in controls, independent of the degree of coronary stenosis.
  • (13) injection of various inflammatory mediators, the vasopressor effect of i.a.
  • (14) The pathogenicity of Mycoplasma pneumoniae in atypical pneumonias can be considered confirmed according to the availabile literature; its importance for other inflammatory diseases of the respiratory tract, particularly for chronic bronchitis, is not yet sufficiently clear.
  • (15) Our previous study demonstrated that acupuncture increased pain threshold of the body, especially in the inflammatory area.
  • (16) We conclude that inflammatory lesions at these sites are not uncommon and that CT scans are diagnostic in the great majority.
  • (17) The IgM antibody was found at high titers in each of 70 patients with inflammatory liver disease and at a low titer in one of six patients with inactive cirrhosis; it was not found in eight carriers with normal liver histology.
  • (18) In the dark cortical zone of the nodes (III group) there occur tissue basophils (mast cells), that, together with increasing number of acidophilic granulocytes and appearance of neutrophilic cells, demonstrates that there is an inflammatory reaction in the organ studied as a response to the lymphocytic suspension injected.
  • (19) Patients with inflammatory bowel disease showed decreased tissue-type plasminogen activator antigen release (t-PA Ag), no significant Von Willebrand antigen release (vWF Ag), and a residual plasminogen activator inhibitor activity (PAI activity) after venous occlusion.
  • (20) These findings suggest that Sch 40120 is a potent anti-inflammatory agent that may be particularly useful in the treatment of inflammatory diseases such as psoriasis in which leukotrienes appear to be major mediators of the pathological symptoms that characterize the disease state.